Gene
INSC
INSC spindle orientation adaptor protein
Explore in graph →CI-GENE-00006209HGNC:33116 ENSG00000188487 NCBI 387755 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28445112,28445469
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Non-Small Cell Lung Cancer (TRACERx, NEJM & Nature 2017) nsclc_tracerx_2017 | Lung Non-Small Cell Carcinoma | Ssm | 39 | 447 | 8.7% | 125 | cbioportal |
| Head and Neck Squamous Cell Carcinoma (Johns Hopkins, Science 2011) |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.