Gene
ABCA5
ATP binding cassette subfamily A member 5
Explore in graph →CI-GENE-00000047HGNC:35 ENSG00000154265 NCBI 23461 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (19)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 27169994
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metastatic Renal Clear Cell Carcinoma (Phase 1 Biomarker Trial, Clin Cancer Res. 2016) - iAtlas Harmonized ccrcc_iatlas_choueiri_2016 | Clear Cell Renal Cell Carcinoma | Ssm | 2 | 16 | 12.5% | 25 | cbioportal |
| Stomach Adenocarcinoma (UHK, Nat Genet 2011) stad_uhongkong | Gastric Adenocarcinoma | Ssm | 2 | 22 | 9.1% | 108 | cbioportal |
| Acinar Cell Carcinoma of the Pancreas (JHU, J Pathol 2014) paac_jhu_2014 | Pancreatic Acinar Cell Carcinoma | Ssm | 2 | 23 | 8.7% | 51 | cbioportal |
| Low-Grade Gliomas (UCSF, Science 2014) lgg_ucsf_2014 | Diffuse Glioma | Ssm | 5 | 61 | 8.2% | 45 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.