Gene
SERPINB3
serpin family B member 3
Explore in graph →CI-GENE-00030349HGNC:10569 ENSG00000057149 NCBI 6317 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pancreatic Adenocarcinoma TCGA-PAAD | Pancreatic Adenocarcinoma | Ssm | 110 | 185 | 59.5% | 85 | gdc |
| Urothelial Cancer Patient Derived Organoids (MSK, 2025) |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.