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CancerIndex

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Lung Small Cell Carcinoma · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Endocrine Neoplasm
Neuroendocrine Neoplasm
Lung Neuroendocrine Neoplasm
Lung Neuroendocrine Carcinoma
Lung Small Cell Carcinoma

Subtype

Lung Small Cell Carcinoma

CI-CAN-00005832SCLCExplore in graph →

381 active trials6 approved drugs6 evidence items

NCIt: C4917
OncoTree: SCLC
DOID: 5409
UMLS CUI: C0149925
MeSH

Overview
Statistics
Survival
Genomics4
Variants & evidence6
Drugs8
Trials1100
Research
Rankings
Sources & provenance

Data completeness5 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A highly aggressive carcinoma with neuroendocrine differentiation that arises from the lung. It is characterized by the presence of malignant small cells and more than 10 mitoses per 2 mm2. Necrosis is frequently seen. Metastatic disease is usually present at the time of diagnosis.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Lung Neuroendocrine CarcinomaSubtype
Small Cell Neuroendocrine CarcinomaSubtype

oncotree

Lung Neuroendocrine NeoplasmSubtype

Children (7)

ncit

Childhood Lung Small Cell Carcinoma
Combined Lung Small Cell Carcinoma2 sub
Lung Small Cell Carcinoma by AJCC v7 Stage
Lung Small Cell Carcinoma Molecular Subtypes5 sub
Lung Small Cell Carcinoma Neuroendocrine Subtypes2 sub
Platinum-Resistant Lung Small Cell Carcinoma

Anatomy

Anatomical sites

EndocrineC3010
Respiratory SystemC3355
ThoracicC3406

Record

Identity

CancerIndex ID: CI-CAN-00005832
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 6
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

Platinum-Sensitive Lung Small Cell Carcinoma

16 descendants in total; counters on this page aggregate over all of them.

1,100 / 381

Publications (all / 5y)

7,638 / 3,148

Evidence items

6

Genes / variants

44 / 6

Drugs (any / approved)

8 / 6

Genomic cohorts

4

Epidemiology / survival obs.

0 / 0

Data updated 17 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (15)

Small Cell Lung Carcinomamesh_heading · MeSH
Lung Oat Cell Carcinomasynonym · NCIt
Lung Small Cell Carcinomasynonym · CIViC
Lung Small Cell Neuroendocrine Carcinomasynonym · NCIt
Oat Cell Carcinoma of Lungsynonym · NCIt
Oat Cell Carcinoma of the Lungsynonym · NCIt
Oat Cell Lung Cancersynonym · MeSH
Oat Cell Lung Carcinomasynonym · NCIt
Small Cell Cancer Of The Lungsynonym · MeSH
Small Cell Carcinoma of Lungsynonym · NCIt
Small Cell Carcinoma of the Lungsynonym · NCIt
Small Cell Lung Cancersynonym · NCIt
Small Cell Lung Carcinomasynonym · NCIt
Small Cell Neuroendocrine Carcinoma of Lungsynonym · NCIt
Small Cell Neuroendocrine Carcinoma of the Lungsynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths128,762countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #1 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Lung Neoplasm (registry level) — open Malignant Lung Neoplasm
US new cases228,058countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #3 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Malignant Lung Neoplasm (registry level) — open Malignant Lung Neoplasm
US age-standardized mortality28per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #1 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Lung Neoplasm (registry level) — open Malignant Lung Neoplasm
Active trials381countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #99 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials202countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #103 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items6countaccepted CIViC items · entity + descendantscivicComputedrank #239 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months581countPubMed records · stored query · 12-month windowpubmedComputedrank #129 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts4countopen GDC projects · entity + descendantsgdcComputedrank #172 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 17 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants