Gene
FAM83H
Explore in graph →CI-GENE-00045114ENSG00000180921 NCBI 286077 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (13)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Ovarian Serous Cystadenocarcinoma TCGA-OV | Ovarian Serous Cystadenocarcinoma | Ssm | 442 | 603 | 73.3% | 43 | gdc |
| Prostate Cancer MDA PCa PDX (MD Anderson, Clin Cancer Res 2024) prad_msk_mdanderson_2023 | unmapped | Ssm | 7 | 44 | 15.9% | 157 | cbioportal |
| Triple Negative Breast Cancer (DLDCCC, Cancer Discov 2022) brca_dldccc_2022 | Invasive Breast Carcinoma | Ssm | 10 | 75 | 13.3% | 13 | cbioportal |
| Glioblastoma (Columbia, Nat Med. 2019) gbm_columbia_2019 | Diffuse Glioma | Ssm | 3 | 32 | 9.4% | 5 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.