Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+64	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9731 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 64 activityPercentile 0 ranking row 2603563
2	▲2	Malignant Esophageal Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 12297 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 76 activityPercentile 52 ranking row 2603564
2	=	Malignant Salivary Gland Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 639 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 28 activityPercentile 4 ranking row 2603565
4	▲1	Malignant Kidney Neoplasm	+20	88	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9188 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 60 activityPercentile 40 ranking row 2603566
5	▲1	Malignant Liver Neoplasm	+16	84	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 18593 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 84 activityPercentile 68 ranking row 2603567
6	▲1	Malignant Colon Neoplasm	+12	80	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 21593 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 88 activityPercentile 76 ranking row 2603570
6	▼3	Malignant Laryngeal Neoplasm	+12	80	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3016 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 40 activityPercentile 28 ranking row 2603569
6	▲3	Malignant Pancreatic Neoplasm	+12	80	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 23177 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 92 activityPercentile 80 ranking row 2603568
9	▲3	Malignant Nasopharyngeal Neoplasm	+8	68	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 541 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 20 activityPercentile 12 ranking row 2603572
9	▲1	Multiple Myeloma	+8	68	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6764 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 56 activityPercentile 48 ranking row 2603571
11	▲8	Malignant Lung Neoplasm	+4	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 76233 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96 ranking row 2603574
11	▼3	Malignant Mesothelioma	+4	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1864 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 36 activityPercentile 32 ranking row 2603573
11	▲11	Malignant Prostate Neoplasm	+4	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 31488 formula percentile(mortality_count) − percentile(publications_5y) activity 52116 burdenPercentile 96 activityPercentile 92 ranking row 2603576
11	▲4	Non-Hodgkin Lymphoma	+4	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11678 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 68 activityPercentile 64 ranking row 2603575
15	▼2	Cutaneous Melanoma	0	44	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5295 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 44 activityPercentile 44 ranking row 2603577
15	▲1	Malignant Bladder Neoplasm	0	44	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11978 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 72 activityPercentile 72 ranking row 2603578
17	▲10	Leukemia	-4	36	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 13732 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 80 activityPercentile 84 ranking row 2603579
18	▲5	Malignant Anal Neoplasm	-8	32	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 466 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 12 activityPercentile 20 ranking row 2603581
18	▼1	Malignant Hypopharyngeal Neoplasm	-8	32	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 319 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 0 activityPercentile 8 ranking row 2603580
18	▲5	Malignant Rectal Neoplasm	-8	32	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6371 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 48 activityPercentile 56 ranking row 2603582
21	▲5	Hodgkin Lymphoma	-12	20	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 614 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 24 activityPercentile 36 ranking row 2603583
21	▲7	Malignant Penile Neoplasm	-12	20	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 347 formula percentile(mortality_count) − percentile(publications_5y) activity 1025 burdenPercentile 4 activityPercentile 16 ranking row 2603584
23	▲8	Malignant Testicular Neoplasm	-16	12	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 401 formula percentile(mortality_count) − percentile(publications_5y) activity 1806 burdenPercentile 8 activityPercentile 24 ranking row 2603585
24	▲8	Malignant Thyroid Gland Neoplasm	-28	8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 919 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 32 activityPercentile 60 ranking row 2603586
25	▲7	Malignant Gastric Neoplasm	-36	4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6628 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 52 activityPercentile 88 ranking row 2603587
26	▲8	Malignant Breast Neoplasm	-84	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 484 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 16 activityPercentile 100 ranking row 2603588

Data updated 16 hours agoSource updated unknown26 eligible entities · inputs hash 503c92c09f1562f039910d96

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Male · all ages · 2018 · top-level cancers
Scope key: geo=USA|sex=male|age=all|year=2018|level=top
Eligible entities: 26
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: 503c92c09f1562f039910d96
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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