Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+60	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 8666 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 60 activityPercentile 0 ranking row 2599622
2	=	Malignant Esophageal Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11697 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 76 activityPercentile 52 ranking row 2599623
2	=	Malignant Kidney Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 8772 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 64 activityPercentile 40 ranking row 2599624
4	=	Malignant Salivary Gland Neoplasm	+20	88	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 581 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 24 activityPercentile 4 ranking row 2599625
5	=	Malignant Colon Neoplasm	+16	84	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 21383 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 92 activityPercentile 76 ranking row 2599627
5	=	Malignant Liver Neoplasm	+16	84	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 15563 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 84 activityPercentile 68 ranking row 2599626
7	=	Malignant Laryngeal Neoplasm	+12	76	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2925 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 40 activityPercentile 28 ranking row 2599628
8	=	Malignant Nasopharyngeal Neoplasm	+8	72	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 454 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 20 activityPercentile 12 ranking row 2599631
8	=	Malignant Pancreatic Neoplasm	+8	72	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 19718 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 88 activityPercentile 80 ranking row 2599629
8	=	Non-Hodgkin Lymphoma	+8	72	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11264 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 72 activityPercentile 64 ranking row 2599630
11	=	Cutaneous Melanoma	+4	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6013 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 48 activityPercentile 44 ranking row 2599633
11	=	Malignant Lung Neoplasm	+4	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 86689 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96 ranking row 2599634
11	=	Malignant Mesothelioma	+4	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2112 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 36 activityPercentile 32 ranking row 2599632
11	=	Malignant Prostate Neoplasm	+4	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 27244 formula percentile(mortality_count) − percentile(publications_5y) activity 52116 burdenPercentile 96 activityPercentile 92 ranking row 2599636
11	=	Multiple Myeloma	+4	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6338 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 52 activityPercentile 48 ranking row 2599635
16	=	Leukemia	-4	40	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 13466 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 80 activityPercentile 84 ranking row 2599637
16	=	Malignant Bladder Neoplasm	-4	40	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 10886 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 68 activityPercentile 72 ranking row 2599638
18	=	Hodgkin Lymphoma	-8	32	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 638 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 28 activityPercentile 36 ranking row 2599639
18	=	Malignant Hypopharyngeal Neoplasm	-8	32	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 268 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 0 activityPercentile 8 ranking row 2599640
20	=	Malignant Anal Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 368 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 8 activityPercentile 20 ranking row 2599643
20	=	Malignant Penile Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 273 formula percentile(mortality_count) − percentile(publications_5y) activity 1025 burdenPercentile 4 activityPercentile 16 ranking row 2599641
20	=	Malignant Rectal Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5483 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 44 activityPercentile 56 ranking row 2599644
20	=	Malignant Testicular Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 386 formula percentile(mortality_count) − percentile(publications_5y) activity 1806 burdenPercentile 12 activityPercentile 24 ranking row 2599642
24	=	Malignant Thyroid Gland Neoplasm	-28	8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 775 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 32 activityPercentile 60 ranking row 2599645
25	=	Malignant Gastric Neoplasm	-32	4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6611 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 56 activityPercentile 88 ranking row 2599646
26	=	Malignant Breast Neoplasm	-84	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 405 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 16 activityPercentile 100 ranking row 2599647

Data updated 16 hours agoSource updated unknown26 eligible entities · inputs hash e157b668f3f2bb158286c4de

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Male · all ages · 2012 · top-level cancers
Scope key: geo=USA|sex=male|age=all|year=2012|level=top
Eligible entities: 26
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: e157b668f3f2bb158286c4de
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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