Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+60	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 7858 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 60 activityPercentile 0 ranking row 2597867
2	=	Malignant Kidney Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 8321 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 64 activityPercentile 40 ranking row 2597868
3	=	Malignant Esophageal Neoplasm	+20	92	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11029 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 72 activityPercentile 52 ranking row 2597869
3	=	Malignant Salivary Gland Neoplasm	+20	92	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 508 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 24 activityPercentile 4 ranking row 2597870
5	=	Malignant Colon Neoplasm	+16	84	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 21450 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 92 activityPercentile 76 ranking row 2597872
5	=	Malignant Liver Neoplasm	+16	84	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 13035 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 84 activityPercentile 68 ranking row 2597871
7	=	Malignant Laryngeal Neoplasm	+12	76	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2867 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 40 activityPercentile 28 ranking row 2597874
7	=	Non-Hodgkin Lymphoma	+12	76	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11165 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 76 activityPercentile 64 ranking row 2597873
9	=	Cutaneous Melanoma	+8	68	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5992 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 52 activityPercentile 44 ranking row 2597875
9	=	Malignant Nasopharyngeal Neoplasm	+8	68	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 449 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 20 activityPercentile 12 ranking row 2597877
9	=	Malignant Pancreatic Neoplasm	+8	68	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 17870 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 88 activityPercentile 80 ranking row 2597876
12	=	Malignant Lung Neoplasm	+4	56	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 87694 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96 ranking row 2597879
12	=	Malignant Mesothelioma	+4	56	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2077 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 36 activityPercentile 32 ranking row 2597878
12	=	Malignant Prostate Neoplasm	+4	56	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 28088 formula percentile(mortality_count) − percentile(publications_5y) activity 52116 burdenPercentile 96 activityPercentile 92 ranking row 2597880
15	=	Multiple Myeloma	0	44	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5842 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 48 activityPercentile 48 ranking row 2597881
16	=	Leukemia	-4	40	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 13018 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 80 activityPercentile 84 ranking row 2597882
16	=	Malignant Bladder Neoplasm	-4	40	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 10042 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 68 activityPercentile 72 ranking row 2597883
18	=	Hodgkin Lymphoma	-8	32	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 690 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 28 activityPercentile 36 ranking row 2597884
18	=	Malignant Hypopharyngeal Neoplasm	-8	32	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 229 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 0 activityPercentile 8 ranking row 2597885
20	=	Malignant Anal Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 302 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 8 activityPercentile 20 ranking row 2597888
20	=	Malignant Penile Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 234 formula percentile(mortality_count) − percentile(publications_5y) activity 1025 burdenPercentile 4 activityPercentile 16 ranking row 2597886
20	=	Malignant Rectal Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5356 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 44 activityPercentile 56 ranking row 2597889
20	=	Malignant Testicular Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 376 formula percentile(mortality_count) − percentile(publications_5y) activity 1806 burdenPercentile 12 activityPercentile 24 ranking row 2597887
24	=	Malignant Thyroid Gland Neoplasm	-28	8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 730 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 32 activityPercentile 60 ranking row 2597890
25	=	Malignant Gastric Neoplasm	-32	4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6665 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 56 activityPercentile 88 ranking row 2597891
26	=	Malignant Breast Neoplasm	-84	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 400 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 16 activityPercentile 100 ranking row 2597892

Data updated 16 hours agoSource updated unknown26 eligible entities · inputs hash ac92a346fb3e3eecaef0bb61

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Male · all ages · 2009 · top-level cancers
Scope key: geo=USA|sex=male|age=all|year=2009|level=top
Eligible entities: 26
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: ac92a346fb3e3eecaef0bb61
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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