Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+70.4	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6318 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 74.1 activityPercentile 3.7 ranking row 2597681
2	=	Malignant Uterine Corpus Neoplasm	+44.4	96.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3333 formula percentile(mortality_count) − percentile(publications_5y) activity 105 burdenPercentile 44.4 activityPercentile 0 ranking row 2597682
3	=	Malignant Kidney Neoplasm	+22.3	92.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4674 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 63 activityPercentile 40.7 ranking row 2597683
4	=	Multiple Myeloma	+18.6	88.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4848 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 66.7 activityPercentile 48.1 ranking row 2597684
5	=	Malignant Colon Neoplasm	+18.5	85.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 21021 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 92.6 activityPercentile 74.1 ranking row 2597685
6	=	Non-Hodgkin Lymphoma	+14.8	81.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9224 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 77.8 activityPercentile 63 ranking row 2597686
7	=	Malignant Pancreatic Neoplasm	+11.1	77.8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 17758 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 88.9 activityPercentile 77.8 ranking row 2597687
8	=	Malignant Vulvar Neoplasm	+11.1	74.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 946 formula percentile(mortality_count) − percentile(publications_5y) activity 870 burdenPercentile 29.6 activityPercentile 18.5 ranking row 2597688
9	=	Malignant Liver Neoplasm	+3.7	70.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6317 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 70.4 activityPercentile 66.7 ranking row 2597690
9	=	Malignant Lung Neoplasm	+3.7	70.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 70387 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96.3 ranking row 2597689
9	=	Malignant Ovarian Neoplasm	+3.7	70.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 14436 formula percentile(mortality_count) − percentile(publications_5y) activity 25793 burdenPercentile 85.2 activityPercentile 81.5 ranking row 2597691
12	=	Malignant Vaginal Neoplasm	+3.7	59.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 398 formula percentile(mortality_count) − percentile(publications_5y) activity 373 burdenPercentile 11.1 activityPercentile 7.4 ranking row 2597692
13	=	Cutaneous Melanoma	-3.7	55.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3207 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 40.7 activityPercentile 44.4 ranking row 2597693
14	=	Malignant Salivary Gland Neoplasm	-3.7	51.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 287 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 7.4 activityPercentile 11.1 ranking row 2597694
15	=	Malignant Breast Neoplasm	-3.7	48.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 40676 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 96.3 activityPercentile 100 ranking row 2597695
15	=	Malignant Laryngeal Neoplasm	-3.7	48.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 763 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 25.9 activityPercentile 29.6 ranking row 2597696
15	=	Malignant Rectal Neoplasm	-3.7	48.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4021 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 51.9 activityPercentile 55.6 ranking row 2597697
18	=	Leukemia	-7.4	37	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9670 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 81.5 activityPercentile 88.9 ranking row 2597698
19	=	Malignant Anal Neoplasm	-11.1	33.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 516 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 14.8 activityPercentile 25.9 ranking row 2597699
20	=	Malignant Mesothelioma	-14.8	29.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 529 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 18.5 activityPercentile 33.3 ranking row 2597700
21	=	Hodgkin Lymphoma	-14.8	25.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 560 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 22.2 activityPercentile 37 ranking row 2597701
21	=	Malignant Hypopharyngeal Neoplasm	-14.8	25.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 50 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 0 activityPercentile 14.8 ranking row 2597702
23	=	Malignant Bladder Neoplasm	-14.8	18.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4159 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 55.6 activityPercentile 70.4 ranking row 2597703
24	=	Malignant Esophageal Neoplasm	-14.9	14.8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2879 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 37 activityPercentile 51.9 ranking row 2597704
25	=	Malignant Nasopharyngeal Neoplasm	-18.5	11.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 213 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 3.7 activityPercentile 22.2 ranking row 2597705
26	=	Malignant Thyroid Gland Neoplasm	-26	7.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 977 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 33.3 activityPercentile 59.3 ranking row 2597706
27	=	Malignant Gastric Neoplasm	-33.3	3.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4519 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 59.3 activityPercentile 92.6 ranking row 2597707
28	=	Malignant Cervical Neoplasm	-37.1	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3909 formula percentile(mortality_count) − percentile(publications_5y) activity 26673 burdenPercentile 48.1 activityPercentile 85.2 ranking row 2597708

Data updated 16 hours agoSource updated unknown28 eligible entities · inputs hash fc746483c447c30320ecb014

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Female · all ages · 2009 · top-level cancers
Scope key: geo=USA|sex=female|age=all|year=2009|level=top
Eligible entities: 28
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: fc746483c447c30320ecb014
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

Download CSV (with attribution)

Burden and lethality metrics depend on registry definitions (site groups, standard population, estimate type). Compare only within one table.