Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+66.7	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6978 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 70.4 activityPercentile 3.7 ranking row 2600606
2	=	Malignant Uterine Corpus Neoplasm	+51.9	96.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4160 formula percentile(mortality_count) − percentile(publications_5y) activity 105 burdenPercentile 51.9 activityPercentile 0 ranking row 2600607
3	=	Malignant Kidney Neoplasm	+22.3	92.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4714 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 63 activityPercentile 40.7 ranking row 2600608
4	=	Multiple Myeloma	+18.6	88.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5523 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 66.7 activityPercentile 48.1 ranking row 2600609
5	=	Malignant Colon Neoplasm	+18.5	85.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 20384 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 92.6 activityPercentile 74.1 ranking row 2600610
6	=	Malignant Vulvar Neoplasm	+14.8	81.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1085 formula percentile(mortality_count) − percentile(publications_5y) activity 870 burdenPercentile 33.3 activityPercentile 18.5 ranking row 2600612
6	=	Non-Hodgkin Lymphoma	+14.8	81.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9102 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 77.8 activityPercentile 63 ranking row 2600611
8	=	Malignant Pancreatic Neoplasm	+11.1	74.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 19664 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 88.9 activityPercentile 77.8 ranking row 2600613
9	=	Malignant Liver Neoplasm	+7.4	70.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 8075 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 74.1 activityPercentile 66.7 ranking row 2600614
10	=	Malignant Lung Neoplasm	+3.7	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 70667 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96.3 ranking row 2600615
10	=	Malignant Ovarian Neoplasm	+3.7	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 14195 formula percentile(mortality_count) − percentile(publications_5y) activity 25793 burdenPercentile 85.2 activityPercentile 81.5 ranking row 2600616
12	=	Malignant Vaginal Neoplasm	+3.7	59.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 430 formula percentile(mortality_count) − percentile(publications_5y) activity 373 burdenPercentile 11.1 activityPercentile 7.4 ranking row 2600617
13	=	Cutaneous Melanoma	-3.7	55.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3163 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 40.7 activityPercentile 44.4 ranking row 2600618
14	=	Malignant Anal Neoplasm	-3.7	51.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 570 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 22.2 activityPercentile 25.9 ranking row 2600620
14	=	Malignant Salivary Gland Neoplasm	-3.7	51.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 300 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 7.4 activityPercentile 11.1 ranking row 2600619
16	=	Malignant Breast Neoplasm	-3.7	44.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 41211 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 96.3 activityPercentile 100 ranking row 2600621
16	=	Malignant Laryngeal Neoplasm	-3.7	44.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 711 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 25.9 activityPercentile 29.6 ranking row 2600622
18	=	Leukemia	-7.4	37	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 10022 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 81.5 activityPercentile 88.9 ranking row 2600623
19	=	Malignant Rectal Neoplasm	-7.5	33.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4133 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 48.1 activityPercentile 55.6 ranking row 2600624
20	=	Malignant Mesothelioma	-14.8	29.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 566 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 18.5 activityPercentile 33.3 ranking row 2600625
21	=	Malignant Hypopharyngeal Neoplasm	-14.8	25.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 53 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 0 activityPercentile 14.8 ranking row 2600626
22	=	Malignant Bladder Neoplasm	-14.8	22.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4484 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 55.6 activityPercentile 70.4 ranking row 2600627
23	=	Malignant Esophageal Neoplasm	-14.9	18.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2982 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 37 activityPercentile 51.9 ranking row 2600628
24	=	Malignant Nasopharyngeal Neoplasm	-18.5	14.8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 180 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 3.7 activityPercentile 22.2 ranking row 2600629
25	=	Hodgkin Lymphoma	-22.2	11.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 444 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 14.8 activityPercentile 37 ranking row 2600630
26	=	Malignant Thyroid Gland Neoplasm	-29.7	7.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1036 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 29.6 activityPercentile 59.3 ranking row 2600631
27	=	Malignant Gastric Neoplasm	-33.3	3.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4525 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 59.3 activityPercentile 92.6 ranking row 2600632
28	=	Malignant Cervical Neoplasm	-40.8	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4115 formula percentile(mortality_count) − percentile(publications_5y) activity 26673 burdenPercentile 44.4 activityPercentile 85.2 ranking row 2600633

Data updated 16 hours agoSource updated unknown28 eligible entities · inputs hash 04b9dfd385dc7a6d7ba37d1d

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Female · all ages · 2014 · top-level cancers
Scope key: geo=USA|sex=female|age=all|year=2014|level=top
Eligible entities: 28
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: 04b9dfd385dc7a6d7ba37d1d
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

Download CSV (with attribution)

Burden and lethality metrics depend on registry definitions (site groups, standard population, estimate type). Compare only within one table.