Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+56	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 7015 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 56 activityPercentile 0 ranking row 2593187
2	=	Malignant Esophageal Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9606 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 76 activityPercentile 52 ranking row 2593188
2	=	Malignant Kidney Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 7524 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 64 activityPercentile 40 ranking row 2593189
4	=	Malignant Salivary Gland Neoplasm	+20	88	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 419 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 24 activityPercentile 4 ranking row 2593190
5	=	Malignant Colon Neoplasm	+16	84	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 23491 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 92 activityPercentile 76 ranking row 2593192
5	=	Non-Hodgkin Lymphoma	+16	84	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11710 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 80 activityPercentile 64 ranking row 2593191
7	=	Malignant Laryngeal Neoplasm	+12	76	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3018 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 40 activityPercentile 28 ranking row 2593193
8	=	Malignant Nasopharyngeal Neoplasm	+8	72	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 415 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 20 activityPercentile 12 ranking row 2593195
8	=	Malignant Pancreatic Neoplasm	+8	72	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 14466 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 88 activityPercentile 80 ranking row 2593194
10	=	Cutaneous Melanoma	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4763 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 48 activityPercentile 44 ranking row 2593197
10	=	Malignant Liver Neoplasm	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 8483 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 72 activityPercentile 68 ranking row 2593200
10	=	Malignant Lung Neoplasm	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 90363 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96 ranking row 2593198
10	=	Malignant Mesothelioma	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1907 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 36 activityPercentile 32 ranking row 2593196
10	=	Malignant Prostate Neoplasm	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 30719 formula percentile(mortality_count) − percentile(publications_5y) activity 52116 burdenPercentile 96 activityPercentile 92 ranking row 2593201
10	=	Multiple Myeloma	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5480 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 52 activityPercentile 48 ranking row 2593199
16	=	Leukemia	0	40	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11894 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 84 activityPercentile 84 ranking row 2593202
16	=	Malignant Hypopharyngeal Neoplasm	0	40	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 257 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 8 activityPercentile 8 ranking row 2593203
18	=	Hodgkin Lymphoma	-4	32	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 725 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 32 activityPercentile 36 ranking row 2593204
18	=	Malignant Bladder Neoplasm	-4	32	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 8343 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 68 activityPercentile 72 ranking row 2593205
20	=	Malignant Penile Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 205 formula percentile(mortality_count) − percentile(publications_5y) activity 1025 burdenPercentile 4 activityPercentile 16 ranking row 2593206
20	=	Malignant Rectal Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4738 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 44 activityPercentile 56 ranking row 2593208
20	=	Malignant Testicular Neoplasm	-12	24	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 335 formula percentile(mortality_count) − percentile(publications_5y) activity 1806 burdenPercentile 12 activityPercentile 24 ranking row 2593207
23	=	Malignant Anal Neoplasm	-20	12	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 185 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 0 activityPercentile 20 ranking row 2593209
24	=	Malignant Gastric Neoplasm	-28	8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 7191 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 60 activityPercentile 88 ranking row 2593210
25	=	Malignant Thyroid Gland Neoplasm	-32	4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 568 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 28 activityPercentile 60 ranking row 2593211
26	=	Malignant Breast Neoplasm	-80	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 415 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 20 activityPercentile 100 ranking row 2593212

Data updated 16 hours agoSource updated unknown26 eligible entities · inputs hash 0fdd26ae4bf9968b6504ff51

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Male · all ages · 2001 · top-level cancers
Scope key: geo=USA|sex=male|age=all|year=2001|level=top
Eligible entities: 26
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: 0fdd26ae4bf9968b6504ff51
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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