Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+60	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9119 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 60 activityPercentile 0 ranking row 2601377
2	=	Malignant Esophageal Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 12187 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 76 activityPercentile 52 ranking row 2601378
2	=	Malignant Kidney Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9502 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 64 activityPercentile 40 ranking row 2601380
2	=	Malignant Salivary Gland Neoplasm	+24	96	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 683 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 28 activityPercentile 4 ranking row 2601379
5	=	Malignant Colon Neoplasm	+16	84	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 21672 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 92 activityPercentile 76 ranking row 2601382
5	=	Malignant Liver Neoplasm	+16	84	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 17414 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 84 activityPercentile 68 ranking row 2601381
7	=	Malignant Laryngeal Neoplasm	+12	76	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2984 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 40 activityPercentile 28 ranking row 2601383
8	=	Malignant Nasopharyngeal Neoplasm	+8	72	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 483 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 20 activityPercentile 12 ranking row 2601385
8	=	Malignant Pancreatic Neoplasm	+8	72	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 21392 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 88 activityPercentile 80 ranking row 2601384
10	=	Malignant Lung Neoplasm	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 83645 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96 ranking row 2601387
10	=	Malignant Mesothelioma	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1890 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 36 activityPercentile 32 ranking row 2601386
10	=	Malignant Prostate Neoplasm	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 28848 formula percentile(mortality_count) − percentile(publications_5y) activity 52116 burdenPercentile 96 activityPercentile 92 ranking row 2601390
10	=	Multiple Myeloma	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6723 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 52 activityPercentile 48 ranking row 2601388
10	=	Non-Hodgkin Lymphoma	+4	64	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11381 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 68 activityPercentile 64 ranking row 2601389
15	=	Cutaneous Melanoma	0	44	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5811 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 44 activityPercentile 44 ranking row 2601391
15	=	Malignant Bladder Neoplasm	0	44	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11587 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 72 activityPercentile 72 ranking row 2601392
17	=	Leukemia	-4	36	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 13349 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 80 activityPercentile 84 ranking row 2601393
17	=	Malignant Hypopharyngeal Neoplasm	-4	36	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 304 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 4 activityPercentile 8 ranking row 2601394
19	=	Malignant Anal Neoplasm	-8	28	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 417 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 12 activityPercentile 20 ranking row 2601395
19	=	Malignant Rectal Neoplasm	-8	28	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5836 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 48 activityPercentile 56 ranking row 2601396
21	=	Hodgkin Lymphoma	-12	20	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 655 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 24 activityPercentile 36 ranking row 2601397
22	=	Malignant Penile Neoplasm	-16	16	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 301 formula percentile(mortality_count) − percentile(publications_5y) activity 1025 burdenPercentile 0 activityPercentile 16 ranking row 2601398
22	=	Malignant Testicular Neoplasm	-16	16	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 374 formula percentile(mortality_count) − percentile(publications_5y) activity 1806 burdenPercentile 8 activityPercentile 24 ranking row 2601399
24	=	Malignant Thyroid Gland Neoplasm	-28	8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 884 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 32 activityPercentile 60 ranking row 2601400
25	=	Malignant Gastric Neoplasm	-32	4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6753 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 56 activityPercentile 88 ranking row 2601401
26	=	Malignant Breast Neoplasm	-84	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 463 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 16 activityPercentile 100 ranking row 2601402

Data updated 16 hours agoSource updated unknown26 eligible entities · inputs hash 3c750c65a61236dae7772c4a

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Male · all ages · 2015 · top-level cancers
Scope key: geo=USA|sex=male|age=all|year=2015|level=top
Eligible entities: 26
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: 3c750c65a61236dae7772c4a
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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