Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	▲1	Malignant Central Nervous System Neoplasm	+66.7	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 7395 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 70.4 activityPercentile 3.7 ranking row 2603233
1	=	Malignant Uterine Corpus Neoplasm	+66.7	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 6416 formula percentile(mortality_count) − percentile(publications_5y) activity 105 burdenPercentile 66.7 activityPercentile 0 ranking row 2603234
3	▲1	Malignant Kidney Neoplasm	+18.6	92.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4946 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 59.3 activityPercentile 40.7 ranking row 2603235
4	▲2	Multiple Myeloma	+14.9	88.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5562 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 63 activityPercentile 48.1 ranking row 2603236
5	=	Malignant Colon Neoplasm	+14.8	85.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 19909 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 88.9 activityPercentile 74.1 ranking row 2603237
6	▲2	Malignant Pancreatic Neoplasm	+14.8	81.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 21737 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 92.6 activityPercentile 77.8 ranking row 2603238
6	▼3	Malignant Vulvar Neoplasm	+14.8	81.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1316 formula percentile(mortality_count) − percentile(publications_5y) activity 870 burdenPercentile 33.3 activityPercentile 18.5 ranking row 2603239
8	▲1	Malignant Liver Neoplasm	+11.1	74.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9092 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 77.8 activityPercentile 66.7 ranking row 2603241
8	▲2	Non-Hodgkin Lymphoma	+11.1	74.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 8609 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 74.1 activityPercentile 63 ranking row 2603240
10	▲5	Malignant Lung Neoplasm	+3.7	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 65847 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96.3 ranking row 2603242
10	▲4	Malignant Ovarian Neoplasm	+3.7	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 13748 formula percentile(mortality_count) − percentile(publications_5y) activity 25793 burdenPercentile 85.2 activityPercentile 81.5 ranking row 2603243
12	▼5	Malignant Vaginal Neoplasm	+3.7	59.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 392 formula percentile(mortality_count) − percentile(publications_5y) activity 373 burdenPercentile 11.1 activityPercentile 7.4 ranking row 2603244
13	=	Malignant Anal Neoplasm	-3.7	55.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 737 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 22.2 activityPercentile 25.9 ranking row 2603246
13	▼1	Malignant Salivary Gland Neoplasm	-3.7	55.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 386 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 7.4 activityPercentile 11.1 ranking row 2603245
15	▲6	Malignant Breast Neoplasm	-3.7	48.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 42465 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 96.3 activityPercentile 100 ranking row 2603247
15	▲1	Malignant Laryngeal Neoplasm	-3.7	48.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 761 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 25.9 activityPercentile 29.6 ranking row 2603248
17	=	Cutaneous Melanoma	-7.4	40.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2904 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 37 activityPercentile 44.4 ranking row 2603249
18	▲1	Leukemia	-7.4	37	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9771 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 81.5 activityPercentile 88.9 ranking row 2603250
19	▲1	Malignant Rectal Neoplasm	-7.5	33.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4290 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 48.1 activityPercentile 55.6 ranking row 2603251
20	▲4	Malignant Esophageal Neoplasm	-11.2	29.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3122 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 40.7 activityPercentile 51.9 ranking row 2603252
21	▲1	Malignant Mesothelioma	-14.8	25.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 562 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 18.5 activityPercentile 33.3 ranking row 2603253
22	▼5	Malignant Hypopharyngeal Neoplasm	-14.8	22.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 91 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 0 activityPercentile 14.8 ranking row 2603254
23	▲4	Malignant Bladder Neoplasm	-14.8	18.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4663 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 55.6 activityPercentile 70.4 ranking row 2603255
24	▼1	Malignant Nasopharyngeal Neoplasm	-18.5	14.8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 171 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 3.7 activityPercentile 22.2 ranking row 2603256
25	▲4	Hodgkin Lymphoma	-22.2	11.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 424 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 14.8 activityPercentile 37 ranking row 2603257
26	▲8	Malignant Thyroid Gland Neoplasm	-29.7	7.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1106 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 29.6 activityPercentile 59.3 ranking row 2603258
27	▲6	Malignant Gastric Neoplasm	-40.7	3.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4415 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 51.9 activityPercentile 92.6 ranking row 2603259
28	▲6	Malignant Cervical Neoplasm	-40.8	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4138 formula percentile(mortality_count) − percentile(publications_5y) activity 26673 burdenPercentile 44.4 activityPercentile 85.2 ranking row 2603260

Data updated 16 hours agoSource updated unknown28 eligible entities · inputs hash 9aaf717339f74c43f7d90b53

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Female · all ages · 2018 · top-level cancers
Scope key: geo=USA|sex=female|age=all|year=2018|level=top
Eligible entities: 28
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: 9aaf717339f74c43f7d90b53
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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