Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+70.4	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5594 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 74.1 activityPercentile 3.7 ranking row 2593001
2	=	Malignant Uterine Corpus Neoplasm	+44.4	96.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3185 formula percentile(mortality_count) − percentile(publications_5y) activity 105 burdenPercentile 44.4 activityPercentile 0 ranking row 2593002
3	=	Multiple Myeloma	+22.3	92.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5234 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 70.4 activityPercentile 48.1 ranking row 2593003
4	=	Malignant Kidney Neoplasm	+18.6	88.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4554 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 59.3 activityPercentile 40.7 ranking row 2593004
5	=	Malignant Colon Neoplasm	+18.5	85.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 24801 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 92.6 activityPercentile 74.1 ranking row 2593006
5	=	Non-Hodgkin Lymphoma	+18.5	85.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 10595 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 81.5 activityPercentile 63 ranking row 2593005
7	=	Malignant Pancreatic Neoplasm	+11.1	77.8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 15336 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 88.9 activityPercentile 77.8 ranking row 2593007
8	=	Malignant Vaginal Neoplasm	+7.4	74.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 382 formula percentile(mortality_count) − percentile(publications_5y) activity 373 burdenPercentile 14.8 activityPercentile 7.4 ranking row 2593008
9	=	Malignant Vulvar Neoplasm	+7.4	70.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 765 formula percentile(mortality_count) − percentile(publications_5y) activity 870 burdenPercentile 25.9 activityPercentile 18.5 ranking row 2593009
10	=	Malignant Lung Neoplasm	+3.7	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 65606 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96.3 ranking row 2593010
10	=	Malignant Ovarian Neoplasm	+3.7	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 14414 formula percentile(mortality_count) − percentile(publications_5y) activity 25793 burdenPercentile 85.2 activityPercentile 81.5 ranking row 2593011
12	=	Malignant Laryngeal Neoplasm	0	59.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 779 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 29.6 activityPercentile 29.6 ranking row 2593012
13	=	Malignant Salivary Gland Neoplasm	-3.7	55.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 266 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 7.4 activityPercentile 11.1 ranking row 2593013
14	=	Malignant Breast Neoplasm	-3.7	51.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 41394 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 96.3 activityPercentile 100 ranking row 2593014
14	=	Malignant Liver Neoplasm	-3.7	51.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4868 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 63 activityPercentile 66.7 ranking row 2593015
16	=	Cutaneous Melanoma	-7.4	44.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2779 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 37 activityPercentile 44.4 ranking row 2593016
17	=	Malignant Rectal Neoplasm	-7.5	40.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3778 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 48.1 activityPercentile 55.6 ranking row 2593017
18	=	Leukemia	-11.1	37	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9638 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 77.8 activityPercentile 88.9 ranking row 2593018
19	=	Malignant Esophageal Neoplasm	-11.2	33.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2923 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 40.7 activityPercentile 51.9 ranking row 2593019
20	=	Malignant Mesothelioma	-14.8	29.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 464 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 18.5 activityPercentile 33.3 ranking row 2593020
21	=	Malignant Anal Neoplasm	-14.8	25.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 326 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 11.1 activityPercentile 25.9 ranking row 2593021
22	=	Hodgkin Lymphoma	-14.8	22.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 598 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 22.2 activityPercentile 37 ranking row 2593022
22	=	Malignant Hypopharyngeal Neoplasm	-14.8	22.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 91 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 0 activityPercentile 14.8 ranking row 2593023
24	=	Malignant Nasopharyngeal Neoplasm	-18.5	14.8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 206 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 3.7 activityPercentile 22.2 ranking row 2593024
25	=	Malignant Bladder Neoplasm	-18.5	11.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3882 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 51.9 activityPercentile 70.4 ranking row 2593025
26	=	Malignant Gastric Neoplasm	-25.9	7.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5128 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 66.7 activityPercentile 92.6 ranking row 2593026
27	=	Malignant Thyroid Gland Neoplasm	-26	3.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 786 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 33.3 activityPercentile 59.3 ranking row 2593027
28	=	Malignant Cervical Neoplasm	-29.6	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4092 formula percentile(mortality_count) − percentile(publications_5y) activity 26673 burdenPercentile 55.6 activityPercentile 85.2 ranking row 2593028

Data updated 16 hours agoSource updated unknown28 eligible entities · inputs hash ac7ea08337328ce76a18ba1e

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Female · all ages · 2001 · top-level cancers
Scope key: geo=USA|sex=female|age=all|year=2001|level=top
Eligible entities: 28
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: ac7ea08337328ce76a18ba1e
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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