Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	▲1	Malignant Central Nervous System Neoplasm	+66.7	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 7855 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 70.4 activityPercentile 3.7 ranking row 2607297
1	=	Malignant Uterine Corpus Neoplasm	+66.7	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 7751 formula percentile(mortality_count) − percentile(publications_5y) activity 105 burdenPercentile 66.7 activityPercentile 0 ranking row 2607298
3	▲2	Malignant Kidney Neoplasm	+14.9	92.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4969 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 55.6 activityPercentile 40.7 ranking row 2607300
3	▲4	Multiple Myeloma	+14.9	92.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5412 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 63 activityPercentile 48.1 ranking row 2607299
5	▲1	Malignant Colon Neoplasm	+14.8	85.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 19244 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 88.9 activityPercentile 74.1 ranking row 2607301
6	▲2	Malignant Liver Neoplasm	+14.8	81.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 10053 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 81.5 activityPercentile 66.7 ranking row 2607303
6	▲2	Malignant Pancreatic Neoplasm	+14.8	81.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 23137 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 92.6 activityPercentile 77.8 ranking row 2607302
6	▼3	Malignant Vulvar Neoplasm	+14.8	81.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1550 formula percentile(mortality_count) − percentile(publications_5y) activity 870 burdenPercentile 33.3 activityPercentile 18.5 ranking row 2607304
9	▲1	Non-Hodgkin Lymphoma	+11.1	70.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 8494 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 74.1 activityPercentile 63 ranking row 2607305
10	▼6	Malignant Vaginal Neoplasm	+7.4	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 434 formula percentile(mortality_count) − percentile(publications_5y) activity 373 burdenPercentile 14.8 activityPercentile 7.4 ranking row 2607306
11	▲5	Malignant Lung Neoplasm	+3.7	63	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 62531 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96.3 ranking row 2607307
11	▲4	Malignant Ovarian Neoplasm	+3.7	63	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 13214 formula percentile(mortality_count) − percentile(publications_5y) activity 25793 burdenPercentile 85.2 activityPercentile 81.5 ranking row 2607308
13	▲1	Malignant Rectal Neoplasm	+3.7	55.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5163 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 59.3 activityPercentile 55.6 ranking row 2607309
14	▼2	Malignant Anal Neoplasm	0	51.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 985 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 25.9 activityPercentile 25.9 ranking row 2607310
15	▼2	Malignant Salivary Gland Neoplasm	-3.7	48.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 372 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 7.4 activityPercentile 11.1 ranking row 2607311
16	▲4	Malignant Breast Neoplasm	-3.7	44.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 42211 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 96.3 activityPercentile 100 ranking row 2607312
17	=	Cutaneous Melanoma	-7.4	40.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2886 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 37 activityPercentile 44.4 ranking row 2607313
18	▼1	Malignant Laryngeal Neoplasm	-7.4	37	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 808 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 22.2 activityPercentile 29.6 ranking row 2607314
19	▲2	Leukemia	-11.1	33.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9912 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 77.8 activityPercentile 88.9 ranking row 2607315
20	▲3	Malignant Esophageal Neoplasm	-11.2	29.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3317 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 40.7 activityPercentile 51.9 ranking row 2607316
21	▲6	Malignant Mesothelioma	-14.8	25.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 611 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 18.5 activityPercentile 33.3 ranking row 2607317
22	▼5	Malignant Hypopharyngeal Neoplasm	-14.8	22.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 94 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 0 activityPercentile 14.8 ranking row 2607318
23	▼1	Malignant Nasopharyngeal Neoplasm	-18.5	18.5	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 209 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 3.7 activityPercentile 22.2 ranking row 2607319
24	▲4	Malignant Bladder Neoplasm	-18.5	14.8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4874 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 51.9 activityPercentile 70.4 ranking row 2607320
25	▲5	Hodgkin Lymphoma	-25.9	11.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 413 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 11.1 activityPercentile 37 ranking row 2607321
26	▲7	Malignant Thyroid Gland Neoplasm	-29.7	7.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1182 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 29.6 activityPercentile 59.3 ranking row 2607322
27	▲6	Malignant Cervical Neoplasm	-40.8	3.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4051 formula percentile(mortality_count) − percentile(publications_5y) activity 26673 burdenPercentile 44.4 activityPercentile 85.2 ranking row 2607323
28	▲7	Malignant Gastric Neoplasm	-44.5	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4416 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 48.1 activityPercentile 92.6 ranking row 2607324

Data updated 16 hours agoSource updated unknown28 eligible entities · inputs hash 79f40c5aadd9775464e6d251

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Female · all ages · 2022 · top-level cancers
Scope key: geo=USA|sex=female|age=all|year=2022|level=top
Eligible entities: 28
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: 79f40c5aadd9775464e6d251
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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