Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+70	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 16804 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 73.3 activityPercentile 3.3 ranking row 2602160
2	=	Malignant Uterine Corpus Neoplasm	+43.3	96.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5962 formula percentile(mortality_count) − percentile(publications_5y) activity 105 burdenPercentile 43.3 activityPercentile 0 ranking row 2602161
3	=	Malignant Pancreatic Neoplasm	+20	93.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 44011 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 96.7 activityPercentile 76.7 ranking row 2602162
4	=	Malignant Colon Neoplasm	+16.7	90	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 41781 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 90 activityPercentile 73.3 ranking row 2602164
4	=	Malignant Kidney Neoplasm	+16.7	90	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 13959 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 60 activityPercentile 43.3 ranking row 2602163
6	=	Malignant Liver Neoplasm	+16.6	83.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 27104 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 83.3 activityPercentile 66.7 ranking row 2602165
7	=	Malignant Esophageal Neoplasm	+13.4	80	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 15321 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 66.7 activityPercentile 53.3 ranking row 2602166
7	=	Non-Hodgkin Lymphoma	+13.4	80	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 20459 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 76.7 activityPercentile 63.3 ranking row 2602167
9	=	Malignant Vulvar Neoplasm	+10	73.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1262 formula percentile(mortality_count) − percentile(publications_5y) activity 870 burdenPercentile 26.7 activityPercentile 16.7 ranking row 2602168
10	=	Multiple Myeloma	+6.7	70	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 12322 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 56.7 activityPercentile 50 ranking row 2602169
11	=	Malignant Salivary Gland Neoplasm	+6.7	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 957 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 16.7 activityPercentile 10 ranking row 2602170
12	=	Malignant Laryngeal Neoplasm	+3.4	63.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3708 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 36.7 activityPercentile 33.3 ranking row 2602171
13	=	Malignant Lung Neoplasm	+3.3	60	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 145849 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96.7 ranking row 2602172
14	=	Cutaneous Melanoma	0	56.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 8056 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 46.7 activityPercentile 46.7 ranking row 2602173
14	=	Malignant Bladder Neoplasm	0	56.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 16657 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 70 activityPercentile 70 ranking row 2602174
14	=	Malignant Vaginal Neoplasm	0	56.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 411 formula percentile(mortality_count) − percentile(publications_5y) activity 373 burdenPercentile 6.7 activityPercentile 6.7 ranking row 2602175
17	=	Malignant Anal Neoplasm	-3.4	46.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1169 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 23.3 activityPercentile 26.7 ranking row 2602176
18	=	Malignant Mesothelioma	-3.4	43.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2651 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 33.3 activityPercentile 36.7 ranking row 2602177
19	=	Malignant Prostate Neoplasm	-6.6	40	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 30486 formula percentile(mortality_count) − percentile(publications_5y) activity 52116 burdenPercentile 86.7 activityPercentile 93.3 ranking row 2602178
20	=	Malignant Nasopharyngeal Neoplasm	-6.7	36.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 709 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 13.3 activityPercentile 20 ranking row 2602179
21	=	Leukemia	-6.7	33.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 23527 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 80 activityPercentile 86.7 ranking row 2602180
21	=	Malignant Breast Neoplasm	-6.7	33.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 42510 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 93.3 activityPercentile 100 ranking row 2602181
21	=	Malignant Rectal Neoplasm	-6.7	33.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 10766 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 50 activityPercentile 56.7 ranking row 2602182
24	=	Malignant Hypopharyngeal Neoplasm	-10	23.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 401 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 3.3 activityPercentile 13.3 ranking row 2602183
25	=	Malignant Ovarian Neoplasm	-16.7	20	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 14193 formula percentile(mortality_count) − percentile(publications_5y) activity 25793 burdenPercentile 63.3 activityPercentile 80 ranking row 2602184
26	=	Hodgkin Lymphoma	-20	16.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1009 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 20 activityPercentile 40 ranking row 2602185
26	=	Malignant Testicular Neoplasm	-20	16.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 425 formula percentile(mortality_count) − percentile(publications_5y) activity 1806 burdenPercentile 10 activityPercentile 30 ranking row 2602186
28	=	Malignant Penile Neoplasm	-23.3	10	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 352 formula percentile(mortality_count) − percentile(publications_5y) activity 1025 burdenPercentile 0 activityPercentile 23.3 ranking row 2602187
29	=	Malignant Thyroid Gland Neoplasm	-30	6.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 1892 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 30 activityPercentile 60 ranking row 2602188
30	=	Malignant Gastric Neoplasm	-36.7	3.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 11158 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 53.3 activityPercentile 90 ranking row 2602189
31	=	Malignant Cervical Neoplasm	-43.3	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4207 formula percentile(mortality_count) − percentile(publications_5y) activity 26673 burdenPercentile 40 activityPercentile 83.3 ranking row 2602190

Data updated 16 hours agoSource updated unknown31 eligible entities · inputs hash 17aedb772017668fffec3111

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · both sexes · all ages · 2017 · top-level cancers
Scope key: geo=USA|sex=all|age=all|year=2017|level=top
Eligible entities: 31
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: 17aedb772017668fffec3111
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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Burden and lethality metrics depend on registry definitions (site groups, standard population, estimate type). Compare only within one table.