Ranking · Unmet Need

Research Gap Index

Burden percentile minus research-activity percentile (publications, last 5 years) within the same scope. Positive values flag cancers with high mortality burden but comparatively little literature. Caveat (Phase 1): literature counts are query-based per entity (query stored on each row); they are not aggregated over descendants.

Computedci-research-gap-v1unit: percentile pointshigher = worseAll metrics

Rank	Δ	Cancer	Research Gap Index (percentile points)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Central Nervous System Neoplasm	+70.4	100	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5644 formula percentile(mortality_count) − percentile(publications_5y) activity 298 burdenPercentile 74.1 activityPercentile 3.7 ranking row 2592416
2	=	Malignant Uterine Corpus Neoplasm	+44.4	96.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3139 formula percentile(mortality_count) − percentile(publications_5y) activity 105 burdenPercentile 44.4 activityPercentile 0 ranking row 2592417
3	=	Multiple Myeloma	+22.3	92.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5318 formula percentile(mortality_count) − percentile(publications_5y) activity 10244 burdenPercentile 70.4 activityPercentile 48.1 ranking row 2592418
4	=	Malignant Kidney Neoplasm	+18.6	88.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4487 formula percentile(mortality_count) − percentile(publications_5y) activity 3700 burdenPercentile 59.3 activityPercentile 40.7 ranking row 2592419
5	=	Malignant Colon Neoplasm	+18.5	85.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 25169 formula percentile(mortality_count) − percentile(publications_5y) activity 18406 burdenPercentile 92.6 activityPercentile 74.1 ranking row 2592421
5	=	Non-Hodgkin Lymphoma	+18.5	85.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 10917 formula percentile(mortality_count) − percentile(publications_5y) activity 17190 burdenPercentile 81.5 activityPercentile 63 ranking row 2592420
7	=	Malignant Pancreatic Neoplasm	+11.1	77.8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 15094 formula percentile(mortality_count) − percentile(publications_5y) activity 25767 burdenPercentile 88.9 activityPercentile 77.8 ranking row 2592422
8	=	Malignant Vaginal Neoplasm	+7.4	74.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 405 formula percentile(mortality_count) − percentile(publications_5y) activity 373 burdenPercentile 14.8 activityPercentile 7.4 ranking row 2592423
9	=	Malignant Vulvar Neoplasm	+7.4	70.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 752 formula percentile(mortality_count) − percentile(publications_5y) activity 870 burdenPercentile 25.9 activityPercentile 18.5 ranking row 2592424
10	=	Malignant Lung Neoplasm	+3.7	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 65016 formula percentile(mortality_count) − percentile(publications_5y) activity 93034 burdenPercentile 100 activityPercentile 96.3 ranking row 2592425
10	=	Malignant Ovarian Neoplasm	+3.7	66.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 14060 formula percentile(mortality_count) − percentile(publications_5y) activity 25793 burdenPercentile 85.2 activityPercentile 81.5 ranking row 2592426
12	=	Malignant Laryngeal Neoplasm	+3.7	59.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 820 formula percentile(mortality_count) − percentile(publications_5y) activity 2031 burdenPercentile 33.3 activityPercentile 29.6 ranking row 2592427
13	=	Malignant Salivary Gland Neoplasm	-3.7	55.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 244 formula percentile(mortality_count) − percentile(publications_5y) activity 474 burdenPercentile 7.4 activityPercentile 11.1 ranking row 2592428
14	=	Malignant Breast Neoplasm	-3.7	51.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 41872 formula percentile(mortality_count) − percentile(publications_5y) activity 133010 burdenPercentile 96.3 activityPercentile 100 ranking row 2592429
14	=	Malignant Liver Neoplasm	-3.7	51.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4740 formula percentile(mortality_count) − percentile(publications_5y) activity 17939 burdenPercentile 63 activityPercentile 66.7 ranking row 2592430
16	=	Cutaneous Melanoma	-7.4	44.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2828 formula percentile(mortality_count) − percentile(publications_5y) activity 4407 burdenPercentile 37 activityPercentile 44.4 ranking row 2592431
17	=	Malignant Rectal Neoplasm	-7.5	40.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3781 formula percentile(mortality_count) − percentile(publications_5y) activity 12506 burdenPercentile 48.1 activityPercentile 55.6 ranking row 2592432
18	=	Leukemia	-11.1	37	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 9594 formula percentile(mortality_count) − percentile(publications_5y) activity 31893 burdenPercentile 77.8 activityPercentile 88.9 ranking row 2592433
19	=	Malignant Esophageal Neoplasm	-11.2	33.3	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 2953 formula percentile(mortality_count) − percentile(publications_5y) activity 10921 burdenPercentile 40.7 activityPercentile 51.9 ranking row 2592434
20	=	Malignant Mesothelioma	-14.8	29.6	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 459 formula percentile(mortality_count) − percentile(publications_5y) activity 2145 burdenPercentile 18.5 activityPercentile 33.3 ranking row 2592435
21	=	Malignant Anal Neoplasm	-14.8	25.9	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 298 formula percentile(mortality_count) − percentile(publications_5y) activity 1291 burdenPercentile 11.1 activityPercentile 25.9 ranking row 2592436
22	=	Hodgkin Lymphoma	-14.8	22.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 601 formula percentile(mortality_count) − percentile(publications_5y) activity 2178 burdenPercentile 22.2 activityPercentile 37 ranking row 2592437
22	=	Malignant Hypopharyngeal Neoplasm	-14.8	22.2	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 72 formula percentile(mortality_count) − percentile(publications_5y) activity 581 burdenPercentile 0 activityPercentile 14.8 ranking row 2592438
24	=	Malignant Nasopharyngeal Neoplasm	-18.5	14.8	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 206 formula percentile(mortality_count) − percentile(publications_5y) activity 952 burdenPercentile 3.7 activityPercentile 22.2 ranking row 2592439
25	=	Malignant Bladder Neoplasm	-18.5	11.1	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 3839 formula percentile(mortality_count) − percentile(publications_5y) activity 18250 burdenPercentile 51.9 activityPercentile 70.4 ranking row 2592440
26	=	Malignant Gastric Neoplasm	-25.9	7.4	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 5317 formula percentile(mortality_count) − percentile(publications_5y) activity 34783 burdenPercentile 66.7 activityPercentile 92.6 ranking row 2592441
27	=	Malignant Cervical Neoplasm	-29.6	3.7	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 4200 formula percentile(mortality_count) − percentile(publications_5y) activity 26673 burdenPercentile 55.6 activityPercentile 85.2 ranking row 2592442
28	=	Malignant Thyroid Gland Neoplasm	-29.7	0	Medium confidence	cdc-uscs pubmed cdc-wonder seer iarc-globocan	inputs deaths 778 formula percentile(mortality_count) − percentile(publications_5y) activity 13792 burdenPercentile 29.6 activityPercentile 59.3 ranking row 2592443

Data updated 16 hours agoSource updated unknown28 eligible entities · inputs hash 9ae3b15c84f06ea54020c92d

Methodology

How this table was built

Formula: percentile(mortality_count) − percentile(publications_5y)
Version: ci-research-gap-v1
Scope: USA · Female · all ages · 2000 · top-level cancers
Scope key: geo=USA|sex=female|age=all|year=2000|level=top
Eligible entities: 28
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: 9ae3b15c84f06ea54020c92d
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality pubmed cdc-wonder seer iarc-globocan
Aggregation: none

Eligibility

requires: mortality_count
publications_5y
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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