Cancer
Malignant Salivary Gland Neoplasm
CI-CAN-00001175Explore in graph →
Top-level63 active trials13 evidence items
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Cancer
CI-CAN-00001175Explore in graph →
Genomics
10 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
23 cases with simple somatic mutation data · 23 cases total · 2026-01-12 · mapped to Pancreatic Acinar Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | SMAD4 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 6 |
| 23 |
| 26.1% |
| cbioportal |
| 5 | LRP1 | Ssm | 4 | 23 | 17.4% | cbioportal |
| 4 | KSR2 | Ssm | 4 | 23 | 17.4% | cbioportal |
| 2 | CAMSAP2 | Ssm | 4 | 23 | 17.4% | cbioportal |
| 3 | JAK1 | Ssm | 4 | 23 | 17.4% | cbioportal |
| 8 | TTN | Ssm | 4 | 23 | 17.4% | cbioportal |
| 7 | TNN | Ssm | 4 | 23 | 17.4% | cbioportal |
| 6 | OBSCN | Ssm | 4 | 23 | 17.4% | cbioportal |
| 33 | NIPBL | Ssm | 3 | 23 | 13% | cbioportal |
| 32 | MUC17 | Ssm | 3 | 23 | 13% | cbioportal |
| 31 | MUC16 | Ssm | 3 | 23 | 13% | cbioportal |
| 30 | MICAL3 | Ssm | 3 | 23 | 13% | cbioportal |
| 28 | MAP3K12 | Ssm | 3 | 23 | 13% | cbioportal |
| 27 | LRP2 | Ssm | 3 | 23 | 13% | cbioportal |
| 26 | KLHL29 | Ssm | 3 | 23 | 13% | cbioportal |
| 25 | KIF21A | Ssm | 3 | 23 | 13% | cbioportal |
| 24 | KCNB2 | Ssm | 3 | 23 | 13% | cbioportal |
| 23 | IGFN1 | Ssm | 3 | 23 | 13% | cbioportal |
| 22 | HYDIN | Ssm | 3 | 23 | 13% | cbioportal |
| 21 | HMCN1 | Ssm | 3 | 23 | 13% | cbioportal |
| 20 | EPB41L3 | Ssm | 3 | 23 | 13% | cbioportal |
| 19 | DYNC1H1 | Ssm | 3 | 23 | 13% | cbioportal |
| 29 | MAST4 | Ssm | 3 | 23 | 13% | cbioportal |
| 40 | SPEG | Ssm | 3 | 23 | 13% | cbioportal |
| 39 | SLCO6A1 | Ssm | 3 | 23 | 13% | cbioportal |
| 38 | RBM27 | Ssm | 3 | 23 | 13% | cbioportal |
| 37 | RB1 | Ssm | 3 | 23 | 13% | cbioportal |
| 36 | PLXNB3 | Ssm | 3 | 23 | 13% | cbioportal |
| 35 | PKHD1 | Ssm | 3 | 23 | 13% | cbioportal |
| 34 | PCNT | Ssm | 3 | 23 | 13% | cbioportal |
Data updated 22 days agoSource updated 2026-01-12
28 cases with simple somatic mutation data · 28 cases total · 2026-01-05 · mapped to Adenoid Cystic Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KDM6A | Ssm | 5 | 28 | 17.9% | cbioportal |
| 2 | ARID1A | Ssm | 4 | 28 | 14.3% | cbioportal |
| 3 | NOTCH1 | Ssm | 3 | 28 | 10.7% | cbioportal |
| 4 | RUNX1 | Ssm | 2 | 28 | 7.1% | cbioportal |
| 12 | PKHD1 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 11 | PIK3CA | Ssm | 1 | 28 | 3.6% | cbioportal |
| 10 | LTK | Ssm | 1 | 28 | 3.6% | cbioportal |
| 9 | EGFR | Ssm | 1 | 28 | 3.6% | cbioportal |
| 8 | CTNNB1 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 7 | BRCA2 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 6 | BAP1 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 5 | AKT1 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 15 | TP53 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 13 | RB1 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 14 | SPEN | Ssm | 1 | 28 | 3.6% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05
25 cases with simple somatic mutation data · 25 cases total · 2026-01-05 · mapped to Adenoid Cystic Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | NOTCH1 | Ssm | 3 | 25 | 12% | cbioportal |
| 13 | TTN | Ssm | 2 | 25 | 8% | cbioportal |
| 12 | SF3B1 | Ssm | 2 | 25 | 8% | cbioportal |
| 11 | RP1L1 | Ssm | 2 | 25 | 8% | cbioportal |
| 10 | RHOA | Ssm | 2 | 25 | 8% | cbioportal |
| 9 | PRKD1 | Ssm | 2 | 25 | 8% | cbioportal |
| 8 | PLXNB1 | Ssm | 2 | 25 | 8% | cbioportal |
| 7 | KMT2D | Ssm | 2 | 25 | 8% | cbioportal |
| 6 | KMT2C | Ssm | 2 | 25 | 8% | cbioportal |
| 5 | KDM6A | Ssm | 2 | 25 | 8% | cbioportal |
| 4 | KANK4 | Ssm | 2 | 25 | 8% | cbioportal |
| 3 | EP300 | Ssm | 2 | 25 | 8% | cbioportal |
| 2 | ABCA4 | Ssm | 2 | 25 | 8% | cbioportal |
| 14 | ZNF292 | Ssm | 2 | 25 | 8% | cbioportal |
| 19 | ADAM2 | Ssm | 1 | 25 | 4% | cbioportal |
| 120 | FLG | Ssm | 1 | 25 | 4% | cbioportal |
| 15 | ABCC5 | Ssm | 1 | 25 | 4% | cbioportal |
| 16 | ACTB | Ssm | 1 | 25 | 4% | cbioportal |
| 17 | ACTL6A | Ssm | 1 | 25 | 4% | cbioportal |
| 18 | ACTN2 | Ssm | 1 | 25 | 4% | cbioportal |
| 20 | ADAMTS13 | Ssm | 1 | 25 | 4% | cbioportal |
| 21 | ADAMTS5 | Ssm | 1 | 25 | 4% | cbioportal |
| 22 | ADCY1 | Ssm | 1 | 25 | 4% | cbioportal |
| 23 | ADNP2 | Ssm | 1 | 25 | 4% | cbioportal |
| 24 | AEBP1 | Ssm | 1 | 25 | 4% | cbioportal |
| 25 | AFG3L2 | Ssm | 1 | 25 | 4% | cbioportal |
| 26 | AGMAT | Ssm | 1 | 25 | 4% | cbioportal |
| 27 | AHNAK2 | Ssm | 1 | 25 | 4% | cbioportal |
| 28 | AIFM3 | Ssm | 1 | 25 | 4% | cbioportal |
| 29 | AJUBA | Ssm | 1 | 25 | 4% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05
65 cases with simple somatic mutation data · 102 cases total · 2026-01-05 · mapped to Adenoid Cystic Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | SPEN | Ssm | 5 | 65 | 7.7% | cbioportal |
| 3 | MUC16 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 4 | NOTCH1 | Ssm | 4 | 65 | 6.2% | cbioportal |
| 2 | CREBBP | Ssm | 4 | 65 | 6.2% | cbioportal |
| 6 | TYW2 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 5 | MUC12 | Ssm | 3 | 65 | 4.6% | cbioportal |
| 26 | ZNF880 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 19 | RTN4R | Ssm | 2 | 65 | 3.1% | cbioportal |
| 21 | SMARCA2 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 22 | TFAP4 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 23 | USP34 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 24 | VWA5B1 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 25 | XKR7 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 13 | IVL | Ssm | 2 | 65 | 3.1% | cbioportal |
| 14 | MAP10 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 15 | MBD3L1 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 16 | MIR152 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 17 | NMRK1 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 18 | OTOF | Ssm | 2 | 65 | 3.1% | cbioportal |
| 20 | SDK1 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 7 | ABCA1 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 8 | ATN1 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 9 | C1ORF167 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 10 | CARD14 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 11 | CHST8 | Ssm | 2 | 65 | 3.1% | cbioportal |
| 12 | CUBN | Ssm | 2 | 65 | 3.1% | cbioportal |
| 30 | ACCS | Ssm | 1 | 65 | 1.5% | cbioportal |
| 29 | ABHD3 | Ssm | 1 | 65 | 1.5% | cbioportal |
| 28 | ABCD2 | Ssm | 1 | 65 | 1.5% | cbioportal |
| 27 | AAK1 | Ssm | 1 | 65 | 1.5% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05
10 cases with simple somatic mutation data · 10 cases total · 2026-01-05 · mapped to Adenoid Cystic Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 2 | TTN | Ssm | 4 | 10 | 40% | cbioportal |
| 1 | MUC12 | Ssm | 4 | 10 | 40% | cbioportal |
| 3 | ZXDB | Ssm | 4 | 10 | 40% | cbioportal |
| 10 | HRNR | Ssm | 3 | 10 | 30% | cbioportal |
| 4 | ADGRV1 | Ssm | 3 | 10 | 30% | cbioportal |
| 5 | CREBBP | Ssm | 3 | 10 | 30% | cbioportal |
| 6 | CUL9 | Ssm | 3 | 10 | 30% | cbioportal |
| 7 | DAGLA | Ssm | 3 | 10 | 30% | cbioportal |
| 8 | FNDC1 | Ssm | 3 | 10 | 30% | cbioportal |
| 9 | GOLGA8M | Ssm | 3 | 10 | 30% | cbioportal |
| 11 | KDM6A | Ssm | 3 | 10 | 30% | cbioportal |
| 12 | LAMC2 | Ssm | 3 | 10 | 30% | cbioportal |
| 13 | LRP1B | Ssm | 3 | 10 | 30% | cbioportal |
| 14 | MEGF6 | Ssm | 3 | 10 | 30% | cbioportal |
| 15 | NANOGNB | Ssm | 3 | 10 | 30% | cbioportal |
| 16 | NOTCH1 | Ssm | 3 | 10 | 30% | cbioportal |
| 17 | OBSCN | Ssm | 3 | 10 | 30% | cbioportal |
| 18 | PLEC | Ssm | 3 | 10 | 30% | cbioportal |
| 19 | POTEF | Ssm | 3 | 10 | 30% | cbioportal |
| 20 | RGPD4 | Ssm | 3 | 10 | 30% | cbioportal |
| 21 | TECPR1 | Ssm | 3 | 10 | 30% | cbioportal |
| 22 | WASHC2A | Ssm | 3 | 10 | 30% | cbioportal |
| 23 | ZFYVE28 | Ssm | 3 | 10 | 30% | cbioportal |
| 24 | AATK | Ssm | 2 | 10 | 20% | cbioportal |
| 28 | ADSS1 | Ssm | 2 | 10 | 20% | cbioportal |
| 29 | AHDC1 | Ssm | 2 | 10 | 20% | cbioportal |
| 94 | IFT172 | Ssm | 2 | 10 | 20% | cbioportal |
| 25 | ABCA8 | Ssm | 2 | 10 | 20% | cbioportal |
| 26 | ADGRL1 | Ssm | 2 | 10 | 20% | cbioportal |
| 27 | ADGRL3 | Ssm | 2 | 10 | 20% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05
60 cases with simple somatic mutation data · 60 cases total · 2026-01-05 · mapped to Adenoid Cystic Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 2 | KDM6A | Ssm | 4 | 60 | 6.7% | cbioportal |
| 1 | CREBBP | Ssm | 4 | 60 | 6.7% | cbioportal |
| 3 | RYR3 | Ssm | 4 | 60 | 6.7% | cbioportal |
| 7 | SMARCA2 | Ssm | 3 | 60 | 5% | cbioportal |
| 4 | MUC16 | Ssm | 3 | 60 | 5% | cbioportal |
| 6 | PIK3CA | Ssm | 3 | 60 | 5% | cbioportal |
| 5 | NOTCH1 | Ssm | 3 | 60 | 5% | cbioportal |
| 8 | TP53 | Ssm | 3 | 60 | 5% | cbioportal |
| 11 | AFF2 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 12 | BUB1B | Ssm | 2 | 60 | 3.3% | cbioportal |
| 13 | CHST5 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 36 | USP29 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 15 | DYSF | Ssm | 2 | 60 | 3.3% | cbioportal |
| 16 | ENC1 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 18 | FOXP2 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 17 | FAT4 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 19 | HSPG2 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 20 | INSRR | Ssm | 2 | 60 | 3.3% | cbioportal |
| 21 | IRAK1 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 22 | LAMA3 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 23 | LPAR4 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 24 | MGA | Ssm | 2 | 60 | 3.3% | cbioportal |
| 25 | MUC4 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 33 | SF3B1 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 34 | TBC1D5 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 35 | THSD7A | Ssm | 2 | 60 | 3.3% | cbioportal |
| 14 | CMTR2 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 37 | ZNF462 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 9 | ACTB | Ssm | 2 | 60 | 3.3% | cbioportal |
| 10 | ADAM2 | Ssm | 2 | 60 | 3.3% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05
12 cases with simple somatic mutation data · 12 cases total · 2026-08-20 · mapped to Breast Adenoid Cystic Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 2 | MYB | Ssm | 2 | 12 | 16.7% | cbioportal |
| 1 | MUC4 | Ssm | 2 | 12 | 16.7% | cbioportal |
| 3 | TLN2 | Ssm | 2 | 12 | 16.7% | cbioportal |
| 20 | CACNA1G | Ssm | 1 | 12 | 8.3% | cbioportal |
| 6 | ADGRF5 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 7 | ALOX15 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 8 | ANKRD29 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 9 | AP1B1 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 10 | ARAF | Ssm | 1 | 12 | 8.3% | cbioportal |
| 11 | ARAP1 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 12 | ARMCX4 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 13 | ASB4 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 14 | ATP10D | Ssm | 1 | 12 | 8.3% | cbioportal |
| 15 | ATP1B2 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 16 | BMS1 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 17 | BRAF | Ssm | 1 | 12 | 8.3% | cbioportal |
| 18 | BRD1 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 19 | C1QTNF9B | Ssm | 1 | 12 | 8.3% | cbioportal |
| 21 | CAPZB | Ssm | 1 | 12 | 8.3% | cbioportal |
| 22 | CASQ1 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 23 | CCDC22 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 24 | CDH1 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 25 | CDH23 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 26 | CDH3 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 27 | CDK11A | Ssm | 1 | 12 | 8.3% | cbioportal |
| 28 | CES1 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 29 | CHAC1 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 30 | CKAP2 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 31 | CNN2 | Ssm | 1 | 12 | 8.3% | cbioportal |
| 32 | COPA | Ssm | 1 | 12 | 8.3% | cbioportal |
Data updated 22 days agoSource updated 2026-08-20
1,049 cases with simple somatic mutation data · 1,049 cases total · 2026-01-05 · mapped to Adenoid Cystic Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | NOTCH1 | Ssm | 232 | 1,049 | 22.1% | cbioportal |
| 2 | KDM6A | Ssm | 138 | 1,049 | 13.2% | cbioportal |
| 3 | ARID1A | Ssm | 120 | 1,049 | 11.4% | cbioportal |
| 4 | KMT2D | Ssm | 111 | 1,049 | 10.6% | cbioportal |
| 5 | BCOR | Ssm | 109 | 1,049 | 10.4% | cbioportal |
| 6 | KMT2C | Ssm | 99 | 1,049 | 9.4% | cbioportal |
| 7 | CREBBP | Ssm | 98 | 1,049 | 9.3% | cbioportal |
| 8 | ARID1B | Ssm | 82 | 1,049 | 7.8% | cbioportal |
| 9 | TERT | Ssm | 82 | 1,049 | 7.8% | cbioportal |
| 10 | TP53 | Ssm | 76 | 1,049 | 7.2% | cbioportal |
| 11 | EP300 | Ssm | 74 | 1,049 | 7.1% | cbioportal |
| 12 | RUNX1 | Ssm | 71 | 1,049 | 6.8% | cbioportal |
| 13 | SPEN | Ssm | 67 | 1,049 | 6.4% | cbioportal |
| 14 | BRCA2 | Ssm | 64 | 1,049 | 6.1% | cbioportal |
| 15 | ATM | Ssm | 59 | 1,049 | 5.6% | cbioportal |
| 16 | FAT1 | Ssm | 57 | 1,049 | 5.4% | cbioportal |
| 17 | PIK3CA | Ssm | 54 | 1,049 | 5.1% | cbioportal |
| 18 | LRP1B | Ssm | 52 | 1,049 | 5% | cbioportal |
| 19 | PIK3R1 | Ssm | 49 | 1,049 | 4.7% | cbioportal |
| 21 | NOTCH3 | Ssm | 44 | 1,049 | 4.2% | cbioportal |
| 20 | MED12 | Ssm | 44 | 1,049 | 4.2% | cbioportal |
| 23 | TSC2 | Ssm | 43 | 1,049 | 4.1% | cbioportal |
| 22 | IRS2 | Ssm | 43 | 1,049 | 4.1% | cbioportal |
| 24 | FAT3 | Ssm | 41 | 1,049 | 3.9% | cbioportal |
| 25 | NTRK1 | Ssm | 40 | 1,049 | 3.8% | cbioportal |
| 27 | SPTA1 | Ssm | 36 | 1,049 | 3.4% | cbioportal |
| 26 | NOTCH2 | Ssm | 36 | 1,049 | 3.4% | cbioportal |
| 28 | PARP4 | Ssm | 35 | 1,049 | 3.3% | cbioportal |
| 29 | FBXW7 | Ssm | 33 | 1,049 | 3.1% | cbioportal |
| 30 | AR | Ssm | 32 | 1,049 | 3.1% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05
24 cases with simple somatic mutation data · 24 cases total · 2026-01-05 · mapped to Adenoid Cystic Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | SPEN | Ssm | 5 | 24 | 20.8% | cbioportal |
| 2 | SMARCA2 | Ssm | 3 | 24 | 12.5% | cbioportal |
| 7 | KDM6A | Ssm | 2 | 24 | 8.3% | cbioportal |
| 6 | FGFR2 | Ssm | 2 | 24 | 8.3% | cbioportal |
| 9 | SLC9C2 | Ssm | 2 | 24 | 8.3% | cbioportal |
| 4 | CREBBP | Ssm | 2 | 24 | 8.3% | cbioportal |
| 3 | CNTNAP5 | Ssm | 2 | 24 | 8.3% | cbioportal |
| 5 | EP300 | Ssm | 2 | 24 | 8.3% | cbioportal |
| 8 | NOTCH1 | Ssm | 2 | 24 | 8.3% | cbioportal |
| 20 | AKAP9 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 19 | AGO2 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 18 | AFDN | Ssm | 1 | 24 | 4.2% | cbioportal |
| 17 | ADGRL4 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 16 | ADCYAP1 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 15 | ADAMTSL3 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 29 | ATM | Ssm | 1 | 24 | 4.2% | cbioportal |
| 13 | ADAM20 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 12 | ACTB | Ssm | 1 | 24 | 4.2% | cbioportal |
| 11 | ACSL6 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 10 | ABCA1 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 84 | GCDH | Ssm | 1 | 24 | 4.2% | cbioportal |
| 14 | ADAMTS10 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 28 | ATIC | Ssm | 1 | 24 | 4.2% | cbioportal |
| 27 | ASCC3 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 26 | ARID5B | Ssm | 1 | 24 | 4.2% | cbioportal |
| 25 | ARID1B | Ssm | 1 | 24 | 4.2% | cbioportal |
| 24 | ARID1A | Ssm | 1 | 24 | 4.2% | cbioportal |
| 23 | APOA2 | Ssm | 1 | 24 | 4.2% | cbioportal |
| 22 | ANKS4B | Ssm | 1 | 24 | 4.2% | cbioportal |
| 21 | ALOX15 | Ssm | 1 | 24 | 4.2% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05
47 cases with simple somatic mutation data · 47 cases total · 2026-01-12 · mapped to Pancreatic Acinar Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | SMAD4 | Ssm | 8 | 47 | 17% | cbioportal |
| 3 | CTNNB1 | Ssm | 6 | 47 | 12.8% | cbioportal |
| 2 | AXIN1 | Ssm | 6 | 47 | 12.8% | cbioportal |
| 6 | RB1 | Ssm | 5 | 47 | 10.6% | cbioportal |
| 4 | NF1 | Ssm | 5 | 47 | 10.6% | cbioportal |
| 5 | PRKAR1A | Ssm | 5 | 47 | 10.6% | cbioportal |
| 7 | CREBBP | Ssm | 4 | 47 | 8.5% | cbioportal |
| 9 | PTEN | Ssm | 4 | 47 | 8.5% | cbioportal |
| 8 | PBRM1 | Ssm | 4 | 47 | 8.5% | cbioportal |
| 155 | SLFN11 | Ssm | 1 | 13 | 7.7% | cbioportal |
| 172 | ZNRF3 | Ssm | 1 | 13 | 7.7% | cbioportal |
| 93 | GNB1 | Ssm | 1 | 13 | 7.7% | cbioportal |
| 154 | SETDB1 | Ssm | 1 | 13 | 7.7% | cbioportal |
| 19 | MGA | Ssm | 3 | 46 | 6.5% | cbioportal |
| 10 | ARID1A | Ssm | 3 | 47 | 6.4% | cbioportal |
| 11 | ASXL1 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 12 | ATM | Ssm | 3 | 47 | 6.4% | cbioportal |
| 13 | BRAF | Ssm | 3 | 47 | 6.4% | cbioportal |
| 14 | BRCA2 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 15 | CDKN2A | Ssm | 3 | 47 | 6.4% | cbioportal |
| 16 | IKBKE | Ssm | 3 | 47 | 6.4% | cbioportal |
| 17 | KMT2D | Ssm | 3 | 47 | 6.4% | cbioportal |
| 18 | MEN1 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 20 | NRAS | Ssm | 3 | 47 | 6.4% | cbioportal |
| 21 | PIK3CG | Ssm | 3 | 47 | 6.4% | cbioportal |
| 22 | POLE | Ssm | 3 | 47 | 6.4% | cbioportal |
| 23 | RARA | Ssm | 3 | 47 | 6.4% | cbioportal |
| 24 | SETD2 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 25 | TP53 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 26 | TSC2 | Ssm | 3 | 47 | 6.4% | cbioportal |
Data updated 22 days agoSource updated 2026-01-12