Gene
TLN2
talin 2
Explore in graph →CI-GENE-00035261HGNC:15447 ENSG00000171914 NCBI 83660 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (25)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26095796
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adenoid Cystic Carcinoma of the Breast (MSK, J Pathol. 2015) acbc_mskcc_2015 | Breast Adenoid Cystic Carcinoma | Ssm | 2 | 12 | 16.7% | 3 | cbioportal |
| NCI-60 Cell Lines (NCI, Cancer Res 2012) cellline_nci60 | unmapped | Ssm | 10 | 60 | 16.7% | 175 | cbioportal |
| Colon Adenocarcinoma (CaseCCC, PNAS 2015) coad_caseccc_2015 | Colon Adenocarcinoma | Ssm | 3 | 29 | 10.3% | 65 | cbioportal |
| The Angiosarcoma Project (Provisional, July 2020) angs_painter_2020 | Angiosarcoma | Ssm | 8 | 83 | 9.6% | 88 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.