Gene
ADCY1
adenylate cyclase 1
Explore in graph →CI-GENE-00000489HGNC:232 ENSG00000164742 NCBI 107 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (18)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26997480
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metastatic Melanoma (UCLA, Cell 2016) mel_ucla_2016 | Melanoma | Ssm | 8 | 38 | 21.1% | 200 | cbioportal |
| Prostate Adenocarcinoma Organoids (MSK, Cell 2014) prad_mskcc_cheny1_organoids_2014 | Prostate Adenocarcinoma | Ssm | 2 | 12 | 16.7% | 20 | cbioportal |
| Uterine Carcinosarcoma (Johns Hopkins, Nat Commun 2014) ucs_jhu_2014 | Uterine Malignant Mixed Mesodermal (Mullerian) Tumor | Ssm | 3 | 22 | 13.6% | 197 | cbioportal |
| Metastatic Renal Clear Cell Carcinoma (Phase 1 Biomarker Trial, Clin Cancer Res. 2016) - iAtlas Harmonized ccrcc_iatlas_choueiri_2016 | Clear Cell Renal Cell Carcinoma | Ssm | 1 | 16 | 6.3% |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.