Gene
ALOX15
arachidonate 15-lipoxygenase
Explore in graph →CI-GENE-00000964HGNC:433 ENSG00000161905 NCBI 246 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (10)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 34635660
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| RAD51B Associated Mixed Cancers (MSK, NPJ Breast Cancer 2021) mixed_msk_tcga_2021 | unmapped | Ssm | 1 | 4 | 25% | 148 | cbioportal |
| Adenoid Cystic Carcinoma of the Breast (MSK, J Pathol. 2015) acbc_mskcc_2015 | Breast Adenoid Cystic Carcinoma | Ssm | 1 | 12 | 8.3% | 7 | cbioportal |
| Acral Melanoma (TGEN, Genome Res 2017) mel_tsam_liang_2017 | Melanoma | Ssm | 3 | 38 | 7.9% | 141 | cbioportal |
| Histiocytosis Cobimetinib (MSK, Nature 2019) histiocytosis_cobi_msk_2019 | Histiocytic and Dendritic Cell Neoplasm | Ssm | 1 | 15 | 6.7% | 43 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.