Cancer Family

Malignant Neoplasm

CI-CAN-00000025CAExplore in graph →

20,102 active trials259 approved drugs3,741 evidence items

NCIt: C9305
OncoTree: MT
DOID: 162
UMLS CUI: C0006826

Data completeness4 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (no data yet)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A neoplasm composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas.

Definition text as published by ncit-evs Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Neoplasm by Special CategoryOther

oncotree

Neoplasm of Uncertain HistogenesisCancer

Children (63)

ncit

Anaplastic Malignant Neoplasm16 sub
B-Cell Malignant Neoplasm11 sub
Carcinoma51 sub
Childhood Malignant Neoplasm25 sub
Chordoma10 sub
Environment-Related Malignant Neoplasm2 sub
Hereditary Malignant Neoplasm17 sub

Anatomy

Anatomical sites

Data not yet available

No anatomical site linked yet.

Immunodeficiency-Related Malignant Neoplasm6 sub

Invasive Malignant Neoplasm4 sub

Leukemia13 sub

Lymphoma12 sub

Malignant Abdominal Neoplasm1 sub

Malignant Bone Marrow Neoplasm7 sub

Malignant Breast Neoplasm10 sub

Malignant Cardiovascular Neoplasm4 sub

Malignant Digestive System Neoplasm13 sub

Malignant Endocrine Neoplasm2 sub

Malignant Eye Neoplasm8 sub

Malignant Fibrohistiocytic Neoplasm1 sub

Malignant Genitourinary System Neoplasm5 sub

Malignant Germ Cell Tumor12 sub

Malignant Giant Cell Neoplasm5 sub

Malignant Head and Neck Neoplasm17 sub

Malignant Histiocytic and Dendritic Cell Neoplasm8 sub

Malignant Lymph Node Neoplasm1 sub

Malignant Mastocytosis3 sub

Malignant Mesothelioma8 sub

Malignant Mixed Neoplasm26 sub

Malignant Musculoskeletal Neoplasm2 sub

Malignant Neoplasm by Grade3 sub

Malignant Neoplasm of Multiple Primary Sites1 sub

Malignant Nervous System Neoplasm5 sub

Malignant Pelvic Neoplasm1 sub

Malignant Peritoneal and Retroperitoneal Neoplasm2 sub

Malignant Respiratory System Neoplasm3 sub

Malignant Skin Neoplasm15 sub

Malignant Soft Tissue Neoplasm9 sub

Malignant Solid Neoplasm6 sub

Malignant Solitary Fibrous Tumor5 sub

Malignant Splenic Neoplasm5 sub

Malignant Thoracic Neoplasm11 sub

Melanoma21 sub

Moderately Differentiated Malignant Neoplasm1 sub

Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusions10 sub

Myeloid Sarcoma11 sub

Nonestrogen-Dependent Malignant Neoplasm

Non-Hematologic Malignancy

Obesity-Related Malignant Neoplasm

Occupational Malignant Neoplasm4 sub

Poorly Differentiated Malignant Neoplasm1 sub

Precursor Lymphoid Neoplasm6 sub

Primary Malignant Neoplasm1 sub

Primitive Neuroectodermal Tumor3 sub

Progesterone Receptor-Positive Malignant Neoplasm1 sub

Sarcoma22 sub

Secondary Malignant Neoplasm13 sub

Solid Pseudopapillary Neoplasm2 sub

Somatic-Type Malignancy

Therapy-Related Malignant Neoplasm7 sub

Undifferentiated Malignant Neoplasm

Well Differentiated Malignant Neoplasm1 sub

5,909 descendants in total; counters on this page aggregate over all of them.

Publications (all / 5y)

0 / 0

Evidence items

3,741

Genes / variants

3,505 / 1,463

Drugs (any / approved)

424 / 259

Genomic cohorts

442

Epidemiology / survival obs.

0 / 0

Data updated 18 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (8)

Cancersynonym · NCIt
Malignancysynonym · NCIt
Malignant Growthsynonym · NCIt
Malignant Neoplastic Diseasesynonym · NCIt
Malignant Tumorsynonym · NCIt
NEOPLASM, MALIGNANTsynonym · NCIt
Tumor, malignant, NOSsynonym · NCIt
Unclassified tumor, malignantsynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

No registry-level ancestor: burden figures are published for the mutually exclusive top-level site groups only, and this entity does not descend from one. Global figures (IARC / GLOBOCAN) stay under license review and SEER awaits credentials.

Active trials20,102countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #1 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials10,885countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #1 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items3,741countaccepted CIViC items · entity + descendantscivicComputedrank #1 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months0countPubMed records · stored query · 12-month windowpubmedComputednot in a current ranking snapshot
Genomic cohorts442countopen GDC projects · entity + descendantsgdcComputedrank #1 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 18 hours agoSource updated unknownregistry figures: none · counters aggregate over descendants