Gene
IVL
involucrin
Explore in graph →CI-GENE-00006484HGNC:6187 ENSG00000163207 NCBI 3713 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (12)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26997480
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metastatic Melanoma (UCLA, Cell 2016) - iAtlas Harmonized mel_iatlas_hugo_ucla_2016 | Melanoma | Ssm | 10 | 27 | 37% | 72 | cbioportal |
| Metastatic Melanoma (UCLA, Cell 2016) mel_ucla_2016 | Melanoma | Ssm | 10 | 38 | 26.3% | 105 | cbioportal |
| Prostate Cancer MDA PCa PDX (MD Anderson, Clin Cancer Res 2024) prad_msk_mdanderson_2023 | unmapped | Ssm | 7 | 44 | 15.9% | 166 | cbioportal |
| Melanoma (MSK, Cell 2017) - iAtlas Harmonized mel_iatlas_riaz_nivolumab_2017 | Melanoma | Ssm | 8 | 73 | 11% | 145 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.