Dasatinib

Curated

← predicts response to

ABL1 Fusionfusion

5 source records aggregated

resistance

Curated

← predicts response to

ABL1 F317LSNV

3 source records aggregated

resistance

Curated

← predicts response to

ABL1 T315ISNV

2 source records aggregated

resistance

Curated

← predicts response to

ABL1 F317VSNV

resistance

Curated

Acute Lymphoblastic Leukemia,Chronic Myeloid Leukemia, BCR-ABL1 Positive

← predicts response to

ABL1 Fusionfusion

13 source records aggregated

resistance

Curated

B Lymphoblastic Leukemia/Lymphoma

← predicts response to

ABL1 Fusionfusion

3 source records aggregated

sensitivity

Curated

Acute Lymphoblastic Leukemia,Chronic Myeloid Leukemia, BCR-ABL1 Positive

← predicts response to

ABL1 Fusionfusion

3 source records aggregated

sensitivity

Curated

← predicts response to

ABL1 V299LSNV

2 source records aggregated

resistance

Curated

Acute Lymphoblastic Leukemia,Chronic Myeloid Leukemia, BCR-ABL1 Positive

← predicts response to

ABL1 E255KSNV

2 source records aggregated

resistance

Curated

← predicts response to

ABL1 F359VSNV

2 source records aggregated

resistance

Curated

Acute Lymphoblastic Leukemia,Chronic Myeloid Leukemia, BCR-ABL1 Positive

← predicts response to

ABL1 T315ISNV

2 source records aggregated

resistance

Curated

B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like

← predicts response to

ABL1 Fusionfusion

sensitivity

Curated

← predicts response to

ABL1 F317LSNV

resistance

Curated

← predicts response to

ABL1 L384MSNV

resistance

Curated

Dasatinib targets …TARGETS15 of 15
→ targets	BCR	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	FGR	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	FRK	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	SRMS	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	LYN	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	HCK	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	BLK	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	YES1	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	LCK	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	SRC	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	FYN	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	KIT	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	EPHA2	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	PDGFRB	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	ABL1	—	INHIBITOR	—	1	Curated	chembl	graph →

Dasatinib targets …TARGETS15 of 15

→ targets

BCR

—

INHIBITOR

—

Curated

→ targets

FGR

—

INHIBITOR

—

Curated

→ targets

FRK

—

INHIBITOR

—

Curated

→ targets

SRMS

—

INHIBITOR

—

Curated

→ targets

LYN

—

INHIBITOR

—

Curated

→ targets

HCK

—

INHIBITOR

—

Curated

→ targets

BLK

—

INHIBITOR

—

Curated

→ targets

YES1

—

INHIBITOR

—

Curated

→ targets

LCK

—

INHIBITOR

—

Curated

→ targets

SRC

—

INHIBITOR

—

Curated

→ targets

FYN

—

INHIBITOR

—

Curated

→ targets

KIT

—

INHIBITOR

—

Curated

→ targets

EPHA2

—

INHIBITOR

—

Curated

→ targets

PDGFRB

—

INHIBITOR

—

Curated

→ targets

ABL1

—

INHIBITOR

—

Curated

Dasatinib investigated for …INVESTIGATED_FOR80 of 80show fewer
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype	supports	A	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Curated	civic	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype 5 source records aggregated	supports	B	Chronic Myeloid Leukemia, BCR-ABL1 Positive	5	Curated	civic	graph →
→ investigated for	Neoplasmcancer_family	unknown	4	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Acute Lymphoblastic Leukemiahematologic_malignancy	unknown	4	Acute Lymphoblastic Leukemia	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype	unknown	4	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype 13 source records aggregated	supports	C	Chronic Myeloid Leukemia, BCR-ABL1 Positive	13	Curated	civic	graph →
→ investigated for	B Lymphoblastic Leukemia/Lymphomahematologic_malignancy 7 source records aggregated	supports	C	B Lymphoblastic Leukemia/Lymphoma	7	Curated	civic	graph →
→ investigated for	B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Likehematologic_malignancy 4 source records aggregated	supports	C	B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like	4	Curated	civic	graph →
→ investigated for	Acute Lymphoblastic Leukemiahematologic_malignancy 3 source records aggregated	supports	C	Acute Lymphoblastic Leukemia	3	Curated	civic	graph →
→ investigated for	B Acute Lymphoblastic Leukemiahematologic_malignancy	supports	C	B Acute Lymphoblastic Leukemia	1	Curated	civic	graph →
→ investigated for	Lung Squamous Cell Carcinomasubtype	supports	C	Lung Squamous Cell Carcinoma	1	Curated	civic	graph →
→ investigated for	Melanomacancer_family	supports	C	Melanoma	1	Curated	civic	graph →
→ investigated for	Lymphoid Leukemiahematologic_malignancy	unknown	3	Lymphoid Leukemia	1	Curated	chembl	graph →
→ investigated for	Prostate Neoplasmsubtype	unknown	3	Prostate Neoplasm	1	Curated	chembl	graph →
→ investigated for	Acute Myeloid Leukemiahematologic_malignancy	unknown	3	Acute Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Leukemiacancer_family	unknown	3	Leukemia	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype 28 source records aggregated	supports	D	Chronic Myeloid Leukemia, BCR-ABL1 Positive	28	Curated	civic	graph →
→ investigated for	Malignant Neoplasmcancer_family 11 source records aggregated	supports	D	Malignant Neoplasm	11	Curated	civic	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype 6 source records aggregated	supports	D	Lung Non-Small Cell Carcinoma	6	Curated	civic	graph →
→ investigated for	B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Likehematologic_malignancy 2 source records aggregated	supports	D	B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like	2	Curated	civic	graph →
→ investigated for	Malignant Colorectal Neoplasmsubtype 2 source records aggregated	supports	D	Malignant Colorectal Neoplasm	2	Curated	civic	graph →
→ investigated for	Acute Lymphoblastic Leukemiahematologic_malignancy	supports	D	Acute Lymphoblastic Leukemia	1	Curated	civic	graph →
→ investigated for	B Lymphoblastic Leukemia/Lymphomahematologic_malignancy	supports	D	B Lymphoblastic Leukemia/Lymphoma	1	Curated	civic	graph →
→ investigated for	Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusionshematologic_malignancy	supports	D	Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusions	1	Curated	civic	graph →
→ investigated for	Melanomacancer_family	supports	D	Melanoma	1	Curated	civic	graph →
→ investigated for	Intrahepatic Cholangiocarcinomasubtype	supports	D	Intrahepatic Cholangiocarcinoma	1	Curated	civic	graph →
→ investigated for	Lung Adenosquamous Carcinomasubtype	supports	D	Lung Adenosquamous Carcinoma	1	Curated	civic	graph →
→ investigated for	Lung Squamous Cell Carcinomasubtype	supports	D	Lung Squamous Cell Carcinoma	1	Curated	civic	graph →
→ investigated for	Liver Neoplasmsubtype	unknown	2	Liver Neoplasm	1	Curated	chembl	graph →
→ investigated for	Paragangliomasubtype	unknown	2	Paraganglioma	1	Curated	chembl	graph →
→ investigated for	Gastrointestinal Stromal Tumorsubtype	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
→ investigated for	Triple-Negative Breast Carcinomamolecular_subtype	unknown	2	Triple-Negative Breast Carcinoma	1	Curated	chembl	graph →
→ investigated for	Gliomasubtype	unknown	2	Glioma	1	Curated	chembl	graph →
→ investigated for	Colon Neoplasmsubtype	unknown	2	Colon Neoplasm	1	Curated	chembl	graph →
→ investigated for	Systemic Mastocytosishematologic_malignancy	unknown	2	Systemic Mastocytosis	1	Curated	chembl	graph →
→ investigated for	Lung Neoplasmcancer_family	unknown	2	Lung Neoplasm	1	Curated	chembl	graph →
→ investigated for	Adenoid Cystic Carcinomahistology	unknown	2	Adenoid Cystic Carcinoma	1	Curated	chembl	graph →
→ investigated for	Diffuse Intrinsic Pontine Gliomasubtype	unknown	2	Diffuse Intrinsic Pontine Glioma	1	Curated	chembl	graph →
→ investigated for	Rectal Neoplasmsubtype	unknown	2	Rectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Brain Neoplasmsubtype	unknown	2	Brain Neoplasm	1	Curated	chembl	graph →
→ investigated for	Pineal Region Neoplasmsubtype	unknown	2	Pineal Region Neoplasm	1	Curated	chembl	graph →
→ investigated for	Neuroblastomasubtype	unknown	2	Neuroblastoma	1	Curated	chembl	graph →
→ investigated for	Gliosarcomasubtype	unknown	2	Gliosarcoma	1	Curated	chembl	graph →
→ investigated for	Cholangiocarcinomasubtype	unknown	2	Cholangiocarcinoma	1	Curated	chembl	graph →
→ investigated for	Lung Small Cell Carcinomasubtype	unknown	2	Lung Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Breast Neoplasmcancer_family	unknown	2	Breast Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lymphomacancer_family	unknown	2	Lymphoma	1	Curated	chembl	graph →
→ investigated for	Polycythemia Verahematologic_malignancy	unknown	2	Polycythemia Vera	1	Curated	chembl	graph →
→ investigated for	Malignant Mesotheliomacancer_family	unknown	2	Malignant Mesothelioma	1	Curated	chembl	graph →
→ investigated for	Melanomacancer_family	unknown	2	Melanoma	1	Curated	chembl	graph →
→ investigated for	Glioblastomasubtype	unknown	2	Glioblastoma	1	Curated	chembl	graph →
→ investigated for	Squamous Cell Carcinomahistology	unknown	2	Squamous Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Pancreatic Neoplasmsubtype	unknown	2	Pancreatic Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype	unknown	2	Lung Non-Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Multiple Myelomahematologic_malignancy	unknown	2	Multiple Myeloma	1	Curated	chembl	graph →
→ investigated for	Chronic Lymphocytic Leukemiahematologic_malignancy	unknown	2	Chronic Lymphocytic Leukemia	1	Curated	chembl	graph →
→ investigated for	Colorectal Neoplasmsubtype	unknown	1	Colorectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy	unknown	1	Peripheral T-Cell Lymphoma, Not Otherwise Specified	1	Curated	chembl	graph →
→ investigated for	Adult T-Cell Leukemia/Lymphomahematologic_malignancy	unknown	1	Adult T-Cell Leukemia/Lymphoma	1	Curated	chembl	graph →
→ investigated for	T-Cell Large Granular Lymphocyte Leukemiahematologic_malignancy	unknown	1	T-Cell Large Granular Lymphocyte Leukemia	1	Curated	chembl	graph →
→ investigated for	Follicular Lymphomahematologic_malignancy	unknown	1	Follicular Lymphoma	1	Curated	chembl	graph →
→ investigated for	Myeloid Leukemiahematologic_malignancy	unknown	1	Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Ovarian Neoplasmsubtype	unknown	1	Ovarian Neoplasm	1	Curated	chembl	graph →
→ investigated for	Peritoneal Neoplasmcancer_family	unknown	1	Peritoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Fallopian Tube Neoplasmsubtype	unknown	1	Fallopian Tube Neoplasm	1	Curated	chembl	graph →
→ investigated for	Central Nervous System Neoplasmcancer_family	unknown	1	Central Nervous System Neoplasm	1	Curated	chembl	graph →
→ investigated for	Mantle Cell Lymphomahematologic_malignancy	unknown	1	Mantle Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Waldenstrom Macroglobulinemiahematologic_malignancy	unknown	1	Waldenstrom Macroglobulinemia	1	Curated	chembl	graph →
→ investigated for	Mycosis Fungoideshematologic_malignancy	unknown	1	Mycosis Fungoides	1	Curated	chembl	graph →
→ investigated for	Sezary Syndromehematologic_malignancy	unknown	1	Sezary Syndrome	1	Curated	chembl	graph →
→ investigated for	Head and Neck Neoplasmcancer_family	unknown	1	Head and Neck Neoplasm	1	Curated	chembl	graph →
→ investigated for	Anaplastic Large Cell Lymphomahematologic_malignancy	unknown	1	Anaplastic Large Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Rhabdomyosarcomasubtype	unknown	1	Rhabdomyosarcoma	1	Curated	chembl	graph →
→ investigated for	Burkitt Lymphomahematologic_malignancy	unknown	1	Burkitt Lymphoma	1	Curated	chembl	graph →
→ investigated for	Myelodysplastic Syndromehematologic_malignancy	unknown	1	Myelodysplastic Syndrome	1	Curated	chembl	graph →
→ investigated for	Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Typehematologic_malignancy	unknown	1	Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type	1	Curated	chembl	graph →
→ investigated for	Hodgkin Lymphomahematologic_malignancy	unknown	1	Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissuehematologic_malignancy	unknown	1	Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue	1	Curated	chembl	graph →
→ investigated for	Non-Hodgkin Lymphomahematologic_malignancy	unknown	1	Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Endometrial Neoplasmsubtype	unknown	0.5	Endometrial Neoplasm	1	Curated	chembl	graph →

Dasatinib investigated for …INVESTIGATED_FOR80 of 80show fewer

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

supports

Curated

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

5 source records aggregated

supports

Curated

→ investigated for

Neoplasmcancer_family

unknown

Neoplasm

Curated

→ investigated for

Acute Lymphoblastic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

unknown

Curated

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

13 source records aggregated

supports

Curated

B Lymphoblastic Leukemia/Lymphoma

→ investigated for

B Lymphoblastic Leukemia/Lymphomahematologic_malignancy

7 source records aggregated

supports

Curated

B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like

→ investigated for

B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Likehematologic_malignancy

4 source records aggregated

supports

Curated

→ investigated for

Acute Lymphoblastic Leukemiahematologic_malignancy

3 source records aggregated

supports

Curated

B Acute Lymphoblastic Leukemia

→ investigated for

B Acute Lymphoblastic Leukemiahematologic_malignancy

supports

Curated

Lung Squamous Cell Carcinoma

→ investigated for

Lung Squamous Cell Carcinomasubtype

supports

Curated

→ investigated for

Melanomacancer_family

supports

Melanoma

Curated

→ investigated for

Lymphoid Leukemiahematologic_malignancy

unknown

Lymphoid Leukemia

Curated

→ investigated for

Prostate Neoplasmsubtype

unknown

Prostate Neoplasm

Curated

→ investigated for

Acute Myeloid Leukemiahematologic_malignancy

unknown

Acute Myeloid Leukemia

Curated

→ investigated for

Leukemiacancer_family

unknown

Leukemia

Curated

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

28 source records aggregated

supports

Curated

→ investigated for

Malignant Neoplasmcancer_family

11 source records aggregated

supports

Malignant Neoplasm

Curated

Lung Non-Small Cell Carcinoma

→ investigated for

Lung Non-Small Cell Carcinomasubtype

6 source records aggregated

supports

Curated

B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like

→ investigated for

B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Likehematologic_malignancy

2 source records aggregated

supports

Curated

Malignant Colorectal Neoplasm

→ investigated for

Malignant Colorectal Neoplasmsubtype

2 source records aggregated

supports

Curated

→ investigated for

Acute Lymphoblastic Leukemiahematologic_malignancy

supports

Curated

B Lymphoblastic Leukemia/Lymphoma

→ investigated for

B Lymphoblastic Leukemia/Lymphomahematologic_malignancy

supports

Curated

Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusions

→ investigated for

Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusionshematologic_malignancy

supports

Curated

→ investigated for

Melanomacancer_family

supports

Melanoma

Curated

Intrahepatic Cholangiocarcinoma

→ investigated for

Intrahepatic Cholangiocarcinomasubtype

supports

Curated

Lung Adenosquamous Carcinoma

→ investigated for

Lung Adenosquamous Carcinomasubtype

supports

Curated

Lung Squamous Cell Carcinoma

→ investigated for

Lung Squamous Cell Carcinomasubtype

supports

Curated

→ investigated for

Liver Neoplasmsubtype

unknown

Liver Neoplasm

Curated

→ investigated for

Paragangliomasubtype

unknown

Paraganglioma

Curated

Gastrointestinal Stromal Tumor

→ investigated for

Gastrointestinal Stromal Tumorsubtype

unknown

Curated

Triple-Negative Breast Carcinoma

→ investigated for

Triple-Negative Breast Carcinomamolecular_subtype

unknown

Curated

→ investigated for

Gliomasubtype

unknown

Glioma

Curated

→ investigated for

Colon Neoplasmsubtype

unknown

Colon Neoplasm

Curated

→ investigated for

Systemic Mastocytosishematologic_malignancy

unknown

Systemic Mastocytosis

Curated

→ investigated for

Lung Neoplasmcancer_family

unknown

Lung Neoplasm

Curated

→ investigated for

Adenoid Cystic Carcinomahistology

unknown

Adenoid Cystic Carcinoma

Curated

Diffuse Intrinsic Pontine Glioma

→ investigated for

Diffuse Intrinsic Pontine Gliomasubtype

unknown

Curated

→ investigated for

Rectal Neoplasmsubtype

unknown

Rectal Neoplasm

Curated

→ investigated for

Brain Neoplasmsubtype

unknown

Brain Neoplasm

Curated

→ investigated for

Pineal Region Neoplasmsubtype

unknown

Pineal Region Neoplasm

Curated

→ investigated for

Neuroblastomasubtype

unknown

Neuroblastoma

Curated

→ investigated for

Gliosarcomasubtype

unknown

Gliosarcoma

Curated

→ investigated for

Cholangiocarcinomasubtype

unknown

Cholangiocarcinoma

Curated

Lung Small Cell Carcinoma

→ investigated for

Lung Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Breast Neoplasmcancer_family

unknown

Breast Neoplasm

Curated

→ investigated for

Lymphomacancer_family

unknown

Lymphoma

Curated

→ investigated for

Polycythemia Verahematologic_malignancy

unknown

Polycythemia Vera

Curated

→ investigated for

Malignant Mesotheliomacancer_family

unknown

Malignant Mesothelioma

Curated

→ investigated for

Melanomacancer_family

unknown

Melanoma

Curated

→ investigated for

Glioblastomasubtype

unknown

Glioblastoma

Curated

→ investigated for

Squamous Cell Carcinomahistology

unknown

Squamous Cell Carcinoma

Curated

→ investigated for

Pancreatic Neoplasmsubtype

unknown

Pancreatic Neoplasm

Curated

Lung Non-Small Cell Carcinoma

→ investigated for

Lung Non-Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Multiple Myelomahematologic_malignancy

unknown

Multiple Myeloma

Curated

Chronic Lymphocytic Leukemia

→ investigated for

Chronic Lymphocytic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Colorectal Neoplasmsubtype

unknown

Colorectal Neoplasm

Curated

Peripheral T-Cell Lymphoma, Not Otherwise Specified

→ investigated for

Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy

unknown

Curated

Adult T-Cell Leukemia/Lymphoma

→ investigated for

Adult T-Cell Leukemia/Lymphomahematologic_malignancy

unknown

Curated

T-Cell Large Granular Lymphocyte Leukemia

→ investigated for

T-Cell Large Granular Lymphocyte Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Follicular Lymphomahematologic_malignancy

unknown

Follicular Lymphoma

Curated

→ investigated for

Myeloid Leukemiahematologic_malignancy

unknown

Myeloid Leukemia

Curated

→ investigated for

Ovarian Neoplasmsubtype

unknown

Ovarian Neoplasm

Curated

→ investigated for

Peritoneal Neoplasmcancer_family

unknown

Peritoneal Neoplasm

Curated

→ investigated for

Fallopian Tube Neoplasmsubtype

unknown

Fallopian Tube Neoplasm

Curated

Central Nervous System Neoplasm

→ investigated for

Central Nervous System Neoplasmcancer_family

unknown

Curated

→ investigated for

Mantle Cell Lymphomahematologic_malignancy

unknown

Mantle Cell Lymphoma

Curated

Waldenstrom Macroglobulinemia

→ investigated for

Waldenstrom Macroglobulinemiahematologic_malignancy

unknown

Curated

→ investigated for

Mycosis Fungoideshematologic_malignancy

unknown

Mycosis Fungoides

Curated

→ investigated for

Sezary Syndromehematologic_malignancy

unknown

Sezary Syndrome

Curated

→ investigated for

Head and Neck Neoplasmcancer_family

unknown

Head and Neck Neoplasm

Curated

Anaplastic Large Cell Lymphoma

→ investigated for

Anaplastic Large Cell Lymphomahematologic_malignancy

unknown

Curated

→ investigated for

Rhabdomyosarcomasubtype

unknown

Rhabdomyosarcoma

Curated

→ investigated for

Burkitt Lymphomahematologic_malignancy

unknown

Burkitt Lymphoma

Curated

→ investigated for

Myelodysplastic Syndromehematologic_malignancy

unknown

Myelodysplastic Syndrome

Curated

Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type

→ investigated for

Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Typehematologic_malignancy

unknown

Curated

→ investigated for

Hodgkin Lymphomahematologic_malignancy

unknown

Hodgkin Lymphoma

Curated

Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue

→ investigated for

Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissuehematologic_malignancy

unknown

Curated

→ investigated for

Non-Hodgkin Lymphomahematologic_malignancy

unknown

Non-Hodgkin Lymphoma

Curated

→ investigated for

Endometrial Neoplasmsubtype

unknown

0.5

Endometrial Neoplasm

Curated

Dasatinib investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 208show all (up to 200)
→ investigated in trials for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype 37 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Chronic Myeloid Leukemia, BCR-ABL1 Positive	37	Observed	clinicaltrials	graph →
→ investigated in trials for	Leukemiacancer_family 30 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Leukemia	30	Observed	clinicaltrials	graph →
→ investigated in trials for	Acute Lymphoblastic Leukemiahematologic_malignancy 28 trials (11 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Acute Lymphoblastic Leukemia	28	Observed	clinicaltrials	graph →
→ investigated in trials for	Acute Myeloid Leukemiahematologic_malignancy 16 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Acute Myeloid Leukemia	16	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Breast Neoplasm 15 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Breast Neoplasm	15	Observed	clinicaltrials	graph →
→ investigated in trials for	Myeloid Leukemiahematologic_malignancy 15 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Myeloid Leukemia	15	Observed	clinicaltrials	graph →
→ investigated in trials for	Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive 13 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Prostate Neoplasm 12 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Prostate Neoplasm	12	Observed	clinicaltrials	graph →
→ investigated in trials for	Multiple Myelomahematologic_malignancy 10 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Multiple Myeloma	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Chronic Lymphocytic Leukemiahematologic_malignancy 8 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Chronic Lymphocytic Leukemia	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Solid Neoplasm 8 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Solid Neoplasm	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Neoplasmcancer_family 7 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Neoplasm	7	Observed	clinicaltrials	graph →
→ investigated in trials for	B Acute Lymphoblastic Leukemiahematologic_malignancy 6 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	B Acute Lymphoblastic Leukemia	6	Observed	clinicaltrials	graph →
→ investigated in trials for	B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1 6 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Non-Small Cell Carcinomasubtype 6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Small Cell Carcinoma	6	Observed	clinicaltrials	graph →

Dasatinib investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 208show all (up to 200)

→ investigated in trials for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

37 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Leukemiacancer_family

30 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Leukemia

Observed

→ investigated in trials for

Acute Lymphoblastic Leukemiahematologic_malignancy

28 trials (11 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Acute Myeloid Leukemiahematologic_malignancy

16 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Acute Myeloid Leukemia

Observed

Malignant Breast Neoplasm

→ investigated in trials for

15 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Breast Neoplasm

Observed

→ investigated in trials for

Myeloid Leukemiahematologic_malignancy

15 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Myeloid Leukemia

Observed

Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated in trials for

13 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

Observed

Malignant Prostate Neoplasm

→ investigated in trials for

12 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Prostate Neoplasm

Observed

→ investigated in trials for

Multiple Myelomahematologic_malignancy

10 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Multiple Myeloma

Observed

Chronic Lymphocytic Leukemia

→ investigated in trials for

Chronic Lymphocytic Leukemiahematologic_malignancy

8 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Solid Neoplasm

8 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Solid Neoplasm

Observed

→ investigated in trials for

Malignant Neoplasmcancer_family

7 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Neoplasm

Observed

B Acute Lymphoblastic Leukemia

→ investigated in trials for

B Acute Lymphoblastic Leukemiahematologic_malignancy

6 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1

→ investigated in trials for

6 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1

Observed

Lung Non-Small Cell Carcinoma

→ investigated in trials for

Lung Non-Small Cell Carcinomasubtype

6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Hematopoietic and Lymphoid Cell Neoplasm,Lymphoma,Malignant Solid Neoplasm+2

Dasatinib studied in …STUDIED_INderived10 of 273show all (up to 200)
→ studied in	NCT02465060Phase 2 · active not recruiting Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · 273 trials list this drug (45 active)	—	—	Hematopoietic and Lymphoid Cell Neoplasm,Lymphoma,Malignant Solid Neoplasm+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT06124157Phase 2 · recruiting A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL) · 273 trials list this drug (45 active)	—	—	B Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT02389309Phase 1 · active not recruiting Dasatinib, Temsirolimus, and Cyclophosphamide in Treating Patients With Advanced, Recurrent, or Refractory Solid Tumors · 273 trials list this drug (45 active)	—	—	Malignant Solid Neoplasm,Brain Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07269470Phase 2 · recruiting Phase II Study Assessing the Safety and Efficacy of Dasatinib in Combination With Ropeginterferon in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase · 273 trials list this drug (45 active)	—	—	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →
→ studied in	NCT05007873Phase 2 · active not recruiting ASTX727 and Dasatinib for the Treatment of Newly Diagnosed Philadelphia Chromosome or BCR-ABL Positive Chronic Myeloid Leukemia in Chronic Phase · 273 trials list this drug (45 active)	—	—	Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →
→ studied in	NCT03516279Phase 2 · active not recruiting Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease · 273 trials list this drug (45 active)	—	—	Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →
→ studied in	NCT02689440Phase 2 · active not recruiting Dasatinib and Venetoclax in Treating Patients With Philadelphia Chromosome Positive or BCR-ABL1 Positive Early Chronic Phase Chronic Myelogenous Leukemia · 273 trials list this drug (45 active)	—	—	Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,Chronic Myeloid Leukemia, Philadelphia Chromosome Positive, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →
→ studied in	NCT01660971Phase 1 · active not recruiting Gemcitabine Hydrochloride, Dasatinib, and Erlotinib Hydrochloride in Treating Patients With Pancreatic Cancer That Is Metastatic or Cannot Be Removed by Surgery · 273 trials list this drug (45 active)	—	—	Pancreatic Carcinoma,Pancreatic Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02559778Phase 2 · recruiting Pediatric Precision Laboratory Advanced Neuroblastoma Therapy · 273 trials list this drug (45 active)	—	—	Neuroblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07804901Phase 2 · not yet recruiting Asciminib Frontline Risk Adapted · 273 trials list this drug (45 active)	—	—	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →

Dasatinib studied in …STUDIED_INderived10 of 273show all (up to 200)

→ studied in

NCT02465060Phase 2 · active not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · 273 trials list this drug (45 active)

—

Observed

B Acute Lymphoblastic Leukemia

→ studied in

NCT06124157Phase 2 · recruiting

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL) · 273 trials list this drug (45 active)

—

Observed

Malignant Solid Neoplasm,Brain Neoplasm

→ studied in

NCT02389309Phase 1 · active not recruiting

Dasatinib, Temsirolimus, and Cyclophosphamide in Treating Patients With Advanced, Recurrent, or Refractory Solid Tumors · 273 trials list this drug (45 active)

—

Observed

→ studied in

NCT07269470Phase 2 · recruiting

Phase II Study Assessing the Safety and Efficacy of Dasatinib in Combination With Ropeginterferon in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase · 273 trials list this drug (45 active)

—

Observed

Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ studied in

NCT05007873Phase 2 · active not recruiting

ASTX727 and Dasatinib for the Treatment of Newly Diagnosed Philadelphia Chromosome or BCR-ABL Positive Chronic Myeloid Leukemia in Chronic Phase · 273 trials list this drug (45 active)

—

Observed

Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ studied in

NCT03516279Phase 2 · active not recruiting

Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease · 273 trials list this drug (45 active)

—

Observed

Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,Chronic Myeloid Leukemia, Philadelphia Chromosome Positive, BCR-ABL1 Positive

→ studied in

NCT02689440Phase 2 · active not recruiting

Dasatinib and Venetoclax in Treating Patients With Philadelphia Chromosome Positive or BCR-ABL1 Positive Early Chronic Phase Chronic Myelogenous Leukemia · 273 trials list this drug (45 active)

—

Observed

Pancreatic Carcinoma,Pancreatic Adenocarcinoma

→ studied in

NCT01660971Phase 1 · active not recruiting

Gemcitabine Hydrochloride, Dasatinib, and Erlotinib Hydrochloride in Treating Patients With Pancreatic Cancer That Is Metastatic or Cannot Be Removed by Surgery · 273 trials list this drug (45 active)

—

Observed

→ studied in

NCT02559778Phase 2 · recruiting

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy · 273 trials list this drug (45 active)

—

Neuroblastoma

Observed