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CancerIndex

CancerIndex is a research and information platform. It is not a physician, does not diagnose, and does not recommend treatment. Population statistics do not predict individual outcomes.

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Non-Hodgkin Lymphoma · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Malignant Neoplasm
Lymphoma
Non-Hodgkin Lymphoma

Hematologic Malignancy

Non-Hodgkin Lymphoma

CI-CAN-00001288NHLExplore in graph →

HematologicTop-level2,168 active trials56 approved drugs83 evidence items

NCIt: C3211
OncoTree: NHL
ICD-10: C82-C86
ICD-10: C96
DOID: 0060060
UMLS CUI: C0024305
MeSH: D008228

Overview
Statistics369
Survival
Genomics30
Variants & evidence83
Drugs23
Trials8119
Research
Rankings
Sources & provenance

Data completeness6 / 7 dimensions

Epidemiology (data present)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

LymphomaCancer Family

oncotree

Lymphoid NeoplasmHematologic Malignancy

Children (30)

ncit

Adult Non-Hodgkin Lymphoma7 sub
AIDS-Related Non-Hodgkin Lymphoma6 sub
B-Cell Non-Hodgkin Lymphoma46 sub
Breast Non-Hodgkin Lymphoma5 sub
Central Nervous System Non-Hodgkin Lymphoma4 sub
Childhood Non-Hodgkin Lymphoma5 sub
Digestive System Non-Hodgkin Lymphoma

Anatomy

Anatomical sites

Hematopoietic and Lymphatic SystemC35813

Record

Identity

CancerIndex ID: CI-CAN-00001288
Entity type: Hematologic Malignancy
Malignant: Yes
Solid / hematologic: Hematologic
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 4
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

10 sub

EBV-Related Non-Hodgkin Lymphoma5 sub

Extranodal Non-Hodgkin Lymphoma2 sub

Head and Neck Non-Hodgkin Lymphoma13 sub

Helicobacter Pylori-Related Non-Hodgkin Lymphoma1 sub

Kidney Non-Hodgkin Lymphoma3 sub

Leukemic Phase of Non-Hodgkin Lymphoma5 sub

Lung Non-Hodgkin Lymphoma4 sub

Lymphoblastic Lymphoma6 sub

Mediastinal Non-Hodgkin Lymphoma5 sub

Non-Hodgkin Lymphoma by Ann Arbor Stage5 sub

Non-Hodgkin Lymphoma by Clinical Course4 sub

Pleural Non-Hodgkin Lymphoma3 sub

Primary Bone Non-Hodgkin Lymphoma1 sub

Primary Cutaneous Non-Hodgkin Lymphoma2 sub

Primary Intraocular Non-Hodgkin Lymphoma2 sub

Prostate Non-Hodgkin Lymphoma4 sub

Retroperitoneal Non-Hodgkin Lymphoma2 sub

Secondary Choroidal Non-Hodgkin Lymphoma

Splenic Non-Hodgkin Lymphoma8 sub

T-Cell Non-Hodgkin Lymphoma33 sub

Transformed Non-Hodgkin Lymphoma2 sub

oncotree

B-Cell Non-Hodgkin Lymphoma46 sub
T-Cell Non-Hodgkin Lymphoma33 sub

611 descendants in total; counters on this page aggregate over all of them.

8,119 / 2,168

Publications (all / 5y)

122,147 / 17,190

Evidence items

83

Genes / variants

382 / 50

Drugs (any / approved)

23 / 56

Genomic cohorts

30

Epidemiology / survival obs.

369 / 0

Data updated 17 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (12)

Non-Hodgkin Lymphomadisplay · CancerIndex top-level set
Lymphoma, Non-Hodgkinmesh_heading · MeSH
Diffuse Small Cleaved Cell Lymphomasynonym · MeSH
Lymphoma, Atypical Diffuse Small Lymphoidsynonym · MeSH
Lymphoma, Nonhodgkinsynonym · MeSH
Lymphoma, Nonhodgkin'ssynonym · MeSH
Lymphoma, Non Hodgkin'ssynonym · MeSH
Lymphoma, Small Cleaved Cell, Diffusesynonym · MeSH
Non-Hodgkin Lymphomasynonym · OncoTree
Non-Hodgkin lymphoma, unspecified sitesynonym · NCIt
Non-Hodgkin's Lymphomasynonym · NCIt
Non-Hodgkin's Lymphoma (NHL)synonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths19,882countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #8 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)
US new cases75,946countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #8 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)
US age-standardized mortality4.5per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #7 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)
Active trials2,168countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #3 of 36 (World · both sexes · all ages · latest · top-level cancers)
Recruiting trials1,128countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #3 of 36 (World · both sexes · all ages · latest · top-level cancers)
Curated evidence items83countaccepted CIViC items · entity + descendantscivicComputedrank #5 of 28 (World · both sexes · all ages · latest · top-level cancers)
Publications, last 12 months2,542countPubMed records · stored query · 12-month windowpubmedComputedrank #13 of 36 (World · both sexes · all ages · latest · top-level cancers)
Genomic cohorts30countopen GDC projects · entity + descendantsgdcComputedrank #3 of 27 (World · both sexes · all ages · latest · top-level cancers)

Data updated 17 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants