Gene
FRK
fyn related Src family tyrosine kinase
Explore in graph →CI-GENE-00002360HGNC:3955 ENSG00000111816 NCBI 2444 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 40100215
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Cancer Radiation (MSK, 2024) rectal_radiation_msk_2024 | Rectal Adenocarcinoma | Ssm | 3 | 17 | 17.6% | 58 | cbioportal |
| Hepatocellular Adenoma (INSERM, Cancer Cell 2014) liad_inserm_fr_2014 | Hepatocellular Adenoma | Ssm | 3 | 46 | 6.5% | 8 | cbioportal |
| Glioblastoma (CPTAC, Cell 2021) gbm_cptac_2021 | Diffuse Glioma | Ssm | 4 | 99 | 4% | 61 | cbioportal |
| Lung Adenocarcinoma (TSP, Nature 2008) luad_tsp | Lung Adenocarcinoma | Ssm | 2 | 163 | 1.2% | 126 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.