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CancerIndex

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Multiple Myeloma · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Malignant Neoplasm
B-Cell Malignant Neoplasm
Multiple Myeloma

Hematologic Malignancy

Multiple Myeloma

CI-CAN-00001244Explore in graph →

HematologicTop-level814 active trials25 approved drugs26 evidence items

NCIt: C3242
OncoTree: PCM
ICD-10: C88
ICD-10: C90
DOID: 9538
UMLS CUI: C0026764
MeSH: D009101

Overview
Statistics369
Survival
Genomics2
Variants & evidence26
Drugs8
Trials3384
Research
Rankings
Sources & provenance

Other

Data completeness6 / 7 dimensions

Epidemiology (data present)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

B-Cell Malignant NeoplasmCancer Family
Plasma Cell NeoplasmHematologic Malignancy

oncotree

B-Cell Non-Hodgkin LymphomaHematologic Malignancy

Children (12)

ncit

Central Nervous System Multiple Myeloma
Multiple Myeloma by ISS Stage
Multiple Myeloma by RISS Stage
Multiple Myeloma Myeloma by DS Stage
Multiple Myeloma, Not Otherwise Specified
Multiple Myeloma with CCND Family Translocation1 sub
Multiple Myeloma with Hyperdiploidy

Anatomy

Anatomical sites

Hematopoietic and Lymphatic SystemC35813

Record

Identity

CancerIndex ID: CI-CAN-00001244
Entity type: Hematologic Malignancy
Malignant: Yes
Solid / hematologic: Hematologic
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 4
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

Multiple Myeloma with MAF Family Translocation

Multiple Myeloma with NSD2 Translocation

Non-Secretory Multiple Myeloma

Osteosclerotic Multiple Myeloma

Smoldering Multiple Myeloma

13 descendants in total; counters on this page aggregate over all of them.

3,384 / 814

Publications (all / 5y)

53,112 / 10,244

Evidence items

26

Genes / variants

61 / 14

Drugs (any / approved)

8 / 25

Genomic cohorts

2

Epidemiology / survival obs.

369 / 0

Data updated 17 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (17)

Multiple Myelomadisplay · CancerIndex top-level set
Multiple Myelomamesh_heading · MeSH
Cell Myeloma, Plasmasynonym · MeSH
Cell Myelomas, Plasmasynonym · MeSH
Disease, Kahlersynonym · MeSH
Kahler diseasesynonym · NCIt
Multiple Myelomasynonym · CIViC
Multiple Myeloma/Plasma Cell Myelomasynonym · NCIt
Multiple Myelomassynonym · MeSH
Myelomasynonym · NCIt
Myeloma Multiplesynonym · MeSH
Myeloma-Multiplessynonym · MeSH
MYELOMA, PLASMA CELL, MALIGNANTsynonym · NCIt
Myelomatosessynonym · MeSH
Myelomatosissynonym · NCIt
Plasma Cell Myelomasynonym · NCIt
Plasma Cell Myeloma/Multiple Myelomasynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths11,967countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #15 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)
US new cases32,131countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #15 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)
US age-standardized mortality2.7per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #13 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)
Active trials814countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #9 of 36 (World · both sexes · all ages · latest · top-level cancers)
Recruiting trials414countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #9 of 36 (World · both sexes · all ages · latest · top-level cancers)
Curated evidence items26countaccepted CIViC items · entity + descendantscivicComputedrank #14 of 28 (World · both sexes · all ages · latest · top-level cancers)
Publications, last 12 months1,734countPubMed records · stored query · 12-month windowpubmedComputedrank #16 of 36 (World · both sexes · all ages · latest · top-level cancers)
Genomic cohorts2countopen GDC projects · entity + descendantsgdcComputedrank #23 of 27 (World · both sexes · all ages · latest · top-level cancers)

Data updated 17 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants