Cancer Family
Malignant Neoplasm
CI-CAN-00000025CAExplore in graph →
20,108 active trials259 approved drugs3,741 evidence items
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Cancer Family
CI-CAN-00000025CAExplore in graph →
Genomics
442 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
80 cases with simple somatic mutation data · 80 cases total · 2026-01-13 · mapped to Uveal Melanoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | GNAQ | Ssm | 40 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 80 |
| 50% |
| cbioportal |
| 2 | GNA11 | Ssm | 36 | 80 | 45% | cbioportal |
| 3 | BAP1 | Ssm | 26 | 80 | 32.5% | cbioportal |
| 4 | SF3B1 | Ssm | 18 | 80 | 22.5% | cbioportal |
| 5 | EIF1AX | Ssm | 10 | 80 | 12.5% | cbioportal |
| 7 | TTN | Ssm | 5 | 80 | 6.3% | cbioportal |
| 6 | MUC16 | Ssm | 5 | 80 | 6.3% | cbioportal |
| 8 | COL14A1 | Ssm | 3 | 80 | 3.8% | cbioportal |
| 9 | CSMD3 | Ssm | 3 | 80 | 3.8% | cbioportal |
| 15 | SRSF2 | Ssm | 3 | 80 | 3.8% | cbioportal |
| 14 | RYR2 | Ssm | 3 | 80 | 3.8% | cbioportal |
| 13 | PLCB2 | Ssm | 3 | 80 | 3.8% | cbioportal |
| 12 | PKHD1L1 | Ssm | 3 | 80 | 3.8% | cbioportal |
| 11 | MYOF | Ssm | 3 | 80 | 3.8% | cbioportal |
| 10 | CYSLTR2 | Ssm | 3 | 80 | 3.8% | cbioportal |
| 108 | XKR4 | Ssm | 2 | 80 | 2.5% | cbioportal |
| 16 | ABR | Ssm | 2 | 80 | 2.5% | cbioportal |
| 17 | ADAMTSL1 | Ssm | 2 | 80 | 2.5% | cbioportal |
| 18 | APC | Ssm | 2 | 80 | 2.5% | cbioportal |
| 19 | ARHGEF17 | Ssm | 2 | 80 | 2.5% | cbioportal |
| 20 | C3 | Ssm | 2 | 80 | 2.5% | cbioportal |
| 21 | CACNA1B | Ssm | 2 | 80 | 2.5% | cbioportal |
| 22 | CACNA1D | Ssm | 2 | 80 | 2.5% | cbioportal |
| 23 | CACNA2D1 | Ssm | 2 | 80 | 2.5% | cbioportal |
| 24 | CADM3 | Ssm | 2 | 80 | 2.5% | cbioportal |
| 25 | CCN4 | Ssm | 2 | 80 | 2.5% | cbioportal |
| 26 | CDH4 | Ssm | 2 | 80 | 2.5% | cbioportal |
| 27 | CEMIP2 | Ssm | 2 | 80 | 2.5% | cbioportal |
| 28 | CENPE | Ssm | 2 | 80 | 2.5% | cbioportal |
| 29 | CEP131 | Ssm | 2 | 80 | 2.5% | cbioportal |
Data updated 22 days agoSource updated 2026-01-13