Gene
PLCB2
phospholipase C beta 2
Explore in graph →CI-GENE-00020056HGNC:9055 ENSG00000137841 NCBI 5330 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22802077
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| NCI-60 Cell Lines (NCI, Cancer Res 2012) cellline_nci60 | unmapped | Ssm | 10 | 60 | 16.7% | 167 | cbioportal |
| Medulloblastoma (Sickkids, Nature 2016) mbl_sickkids_2016 | Medulloblastoma | Ssm | 3 | 46 | 6.5% | 47 | cbioportal |
| Hepatocellular Adenoma (INSERM, Cancer Cell 2014) liad_inserm_fr_2014 | Hepatocellular Adenoma | Ssm | 2 | 46 | 4.3% | 86 | cbioportal |
| Uveal Melanoma (TCGA, Firehose Legacy) uvm_tcga | Uveal Melanoma | Ssm | 3 | 80 | 3.8% | 13 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.