Cancer Family
Malignant Neoplasm
CI-CAN-00000025CAExplore in graph →
20,108 active trials259 approved drugs3,741 evidence items
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Cancer Family
CI-CAN-00000025CAExplore in graph →
Genomics
442 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
73 cases with simple somatic mutation data · 107 cases total · 2026-02-11 · mapped to Melanoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | MUC16 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 36 |
| 73 |
| 49.3% |
| cbioportal |
| 2 | TTN | Ssm | 35 | 73 | 47.9% | cbioportal |
| 3 | BRAF | Ssm | 25 | 73 | 34.2% | cbioportal |
| 4 | PCLO | Ssm | 25 | 73 | 34.2% | cbioportal |
| 6 | DNAH5 | Ssm | 21 | 73 | 28.8% | cbioportal |
| 7 | OBSCN | Ssm | 21 | 73 | 28.8% | cbioportal |
| 5 | CSMD1 | Ssm | 21 | 73 | 28.8% | cbioportal |
| 9 | NRAS | Ssm | 20 | 73 | 27.4% | cbioportal |
| 8 | LRP1B | Ssm | 20 | 73 | 27.4% | cbioportal |
| 10 | PKHD1L1 | Ssm | 19 | 73 | 26% | cbioportal |
| 14 | ZFHX4 | Ssm | 18 | 73 | 24.7% | cbioportal |
| 12 | DNAH8 | Ssm | 18 | 73 | 24.7% | cbioportal |
| 13 | FAT3 | Ssm | 18 | 73 | 24.7% | cbioportal |
| 11 | ADGRV1 | Ssm | 18 | 73 | 24.7% | cbioportal |
| 16 | MUC17 | Ssm | 17 | 73 | 23.3% | cbioportal |
| 15 | CACNA1A | Ssm | 17 | 73 | 23.3% | cbioportal |
| 19 | RP1 | Ssm | 16 | 73 | 21.9% | cbioportal |
| 18 | FLG | Ssm | 16 | 73 | 21.9% | cbioportal |
| 17 | CSMD2 | Ssm | 16 | 73 | 21.9% | cbioportal |
| 22 | COL6A3 | Ssm | 15 | 73 | 20.5% | cbioportal |
| 20 | ADAMTS20 | Ssm | 15 | 73 | 20.5% | cbioportal |
| 21 | ANK3 | Ssm | 15 | 73 | 20.5% | cbioportal |
| 27 | WDFY4 | Ssm | 14 | 73 | 19.2% | cbioportal |
| 23 | ASXL3 | Ssm | 14 | 73 | 19.2% | cbioportal |
| 26 | MXRA5 | Ssm | 14 | 73 | 19.2% | cbioportal |
| 25 | DSP | Ssm | 14 | 73 | 19.2% | cbioportal |
| 24 | DNAH6 | Ssm | 14 | 73 | 19.2% | cbioportal |
| 30 | CRB1 | Ssm | 13 | 73 | 17.8% | cbioportal |
| 33 | DSCAM | Ssm | 13 | 73 | 17.8% | cbioportal |
| 32 | DNAH9 | Ssm | 13 | 73 | 17.8% | cbioportal |
Data updated 22 days agoSource updated 2026-02-11