Cancer Family
Malignant Neoplasm
CI-CAN-00000025CAExplore in graph →
20,108 active trials259 approved drugs3,741 evidence items
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Cancer Family
CI-CAN-00000025CAExplore in graph →
Genomics
442 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
504 cases with simple somatic mutation data · 504 cases total · Data Release 46.0 · mapped to Lung Squamous Cell Carcinoma ONTOLOGY_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TP53 |
| Ssm |
| 453 |
| 504 |
| 89.9% |
| gdc |
| 5 | EEF1AKMT4-ECE2 | Ssm | 444 | 504 | 88.1% | gdc |
| 8 | EPHB3 | Ssm | 444 | 504 | 88.1% | gdc |
| 6 | ATP11B | Ssm | 444 | 504 | 88.1% | gdc |
| 4 | ABCC5 | Ssm | 444 | 504 | 88.1% | gdc |
| 7 | CCDC39 | Ssm | 444 | 504 | 88.1% | gdc |
| 2 | DVL3 | Ssm | 444 | 504 | 88.1% | gdc |
| 3 | KLHL6 | Ssm | 444 | 504 | 88.1% | gdc |
| 12 | MECOM | Ssm | 443 | 504 | 87.9% | gdc |
| 19 | ABCF3 | Ssm | 443 | 504 | 87.9% | gdc |
| 22 | MAP6D1 | Ssm | 443 | 504 | 87.9% | gdc |
| 16 | MAGEF1 | Ssm | 443 | 504 | 87.9% | gdc |
| 17 | ZBBX | Ssm | 443 | 504 | 87.9% | gdc |
| 9 | HTR3E | Ssm | 443 | 504 | 87.9% | gdc |
| 11 | HTR3C | Ssm | 443 | 504 | 87.9% | gdc |
| 23 | CHRD | Ssm | 443 | 504 | 87.9% | gdc |
| 20 | CLCN2 | Ssm | 443 | 504 | 87.9% | gdc |
| 13 | SOX2 | Ssm | 443 | 504 | 87.9% | gdc |
| 18 | TNIK | Ssm | 443 | 504 | 87.9% | gdc |
| 21 | DCUN1D1 | Ssm | 443 | 504 | 87.9% | gdc |
| 24 | EIF2B5 | Ssm | 443 | 504 | 87.9% | gdc |
| 10 | ACTRT3 | Ssm | 443 | 504 | 87.9% | gdc |
| 26 | FNDC3B | Ssm | 443 | 504 | 87.9% | gdc |
| 14 | PARL | Ssm | 443 | 504 | 87.9% | gdc |
| 25 | VPS8 | Ssm | 443 | 504 | 87.9% | gdc |
| 15 | AC131160.1 | Ssm | 443 | 504 | 87.9% | gdc |
| 45 | NLGN1 | Ssm | 442 | 504 | 87.7% | gdc |
| 29 | SAMD7 | Ssm | 442 | 504 | 87.7% | gdc |
| 39 | AP2M1 | Ssm | 442 | 504 | 87.7% | gdc |
| 38 | C3orf70 | Ssm | 442 | 504 | 87.7% | gdc |
Data updated 22 days agoSource updated Data Release 46.0