Vorinostat

Curated

← predicts response to

TP53 G245SSNV

sensitivity

Curated

← predicts response to

TP53 R273CSNV

sensitivity

Curated

← predicts response to

TP53 H193RSNV

sensitivity

Curated

← predicts response to

TP53 R175HSNV

sensitivity

Curated

← predicts response to

RAD23B EXPRESSIONexpression

sensitivity

Curated

← predicts response to

BAP1 Mutationother

sensitivity

Uveal Melanoma

Curated

← predicts response to

BAP1 Lossdeletion_cna

sensitivity

Malignant Mesothelioma

Curated

Vorinostat targets …TARGETS4 of 4
→ targets	HDAC2	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	HDAC1	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	HDAC3	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	HDAC6	—	INHIBITOR	—	1	Curated	chembl	graph →

Vorinostat targets …TARGETS4 of 4

→ targets

HDAC2

—

INHIBITOR

—

Curated

→ targets

HDAC1

—

INHIBITOR

—

Curated

→ targets

HDAC3

—

INHIBITOR

—

Curated

→ targets

HDAC6

—

INHIBITOR

—

Curated

T-Cell Non-Hodgkin Lymphoma

Vorinostat investigated for …INVESTIGATED_FOR74 of 74show fewer
→ investigated for	T-Cell Non-Hodgkin Lymphomahematologic_malignancy	unknown	4	T-Cell Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Neoplasmcancer_family	unknown	4	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Primary Cutaneous T-Cell Non-Hodgkin Lymphomahematologic_malignancy	unknown	4	Primary Cutaneous T-Cell Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Malignant Colorectal Neoplasmsubtype	supports	C	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ investigated for	Sarcomacancer_family	supports	C	Sarcoma	1	Curated	civic	graph →
→ investigated for	Lung Neoplasmcancer_family	unknown	3	Lung Neoplasm	1	Curated	chembl	graph →
→ investigated for	Malignant Mesotheliomacancer_family	unknown	3	Malignant Mesothelioma	1	Curated	chembl	graph →
→ investigated for	Acute Myeloid Leukemiahematologic_malignancy	unknown	3	Acute Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Lymphomacancer_family	unknown	3	Lymphoma	1	Curated	chembl	graph →
→ investigated for	Multiple Myelomahematologic_malignancy	unknown	3	Multiple Myeloma	1	Curated	chembl	graph →
→ investigated for	Sarcomacancer_family	supports	D	Sarcoma	1	Curated	civic	graph →
→ investigated for	Uveal Melanomasubtype	supports	D	Uveal Melanoma	1	Curated	civic	graph →
→ investigated for	Thyroid Gland Follicular Carcinomacancer_family	unknown	2	Thyroid Gland Follicular Carcinoma	1	Curated	chembl	graph →
→ investigated for	Uveal Melanomasubtype	unknown	2	Uveal Melanoma	1	Curated	chembl	graph →
→ investigated for	Bladder Neoplasmsubtype	unknown	2	Bladder Neoplasm	1	Curated	chembl	graph →
→ investigated for	Colon Neoplasmsubtype	unknown	2	Colon Neoplasm	1	Curated	chembl	graph →
→ investigated for	Acute Biphenotypic Leukemiahematologic_malignancy	unknown	2	Acute Biphenotypic Leukemia	1	Curated	chembl	graph →
→ investigated for	Brain Neoplasmsubtype	unknown	2	Brain Neoplasm	1	Curated	chembl	graph →
→ investigated for	Rectal Neoplasmsubtype	unknown	2	Rectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Polycythemia Verahematologic_malignancy	unknown	2	Polycythemia Vera	1	Curated	chembl	graph →
→ investigated for	Thyroid Gland Neoplasmsubtype	unknown	2	Thyroid Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Colorectal Neoplasmsubtype	unknown	2	Colorectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Essential Thrombocythemiahematologic_malignancy	unknown	2	Essential Thrombocythemia	1	Curated	chembl	graph →
→ investigated for	Mantle Cell Lymphomahematologic_malignancy	unknown	2	Mantle Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Sezary Syndromehematologic_malignancy	unknown	2	Sezary Syndrome	1	Curated	chembl	graph →
→ investigated for	Non-Hodgkin Lymphomahematologic_malignancy	unknown	2	Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Breast Neoplasmcancer_family	unknown	2	Breast Neoplasm	1	Curated	chembl	graph →
→ investigated for	Astrocytic Tumorsubtype	unknown	2	Astrocytic Tumor	1	Curated	chembl	graph →
→ investigated for	Prostate Neoplasmsubtype	unknown	2	Prostate Neoplasm	1	Curated	chembl	graph →
→ investigated for	Leukemiacancer_family	unknown	2	Leukemia	1	Curated	chembl	graph →
→ investigated for	Glioblastomasubtype	unknown	2	Glioblastoma	1	Curated	chembl	graph →
→ investigated for	Acute Lymphoblastic Leukemiahematologic_malignancy	unknown	2	Acute Lymphoblastic Leukemia	1	Curated	chembl	graph →
→ investigated for	Hodgkin Lymphomahematologic_malignancy	unknown	2	Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissuehematologic_malignancy	unknown	2	Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue	1	Curated	chembl	graph →
→ investigated for	Ovarian Neoplasmsubtype	unknown	2	Ovarian Neoplasm	1	Curated	chembl	graph →
→ investigated for	Chronic Lymphocytic Leukemiahematologic_malignancy	unknown	2	Chronic Lymphocytic Leukemia	1	Curated	chembl	graph →
→ investigated for	Follicular Lymphomahematologic_malignancy	unknown	2	Follicular Lymphoma	1	Curated	chembl	graph →
→ investigated for	Gliosarcomasubtype	unknown	2	Gliosarcoma	1	Curated	chembl	graph →
→ investigated for	Mycosis Fungoideshematologic_malignancy	unknown	2	Mycosis Fungoides	1	Curated	chembl	graph →
→ investigated for	Renal Cell Carcinomasubtype	unknown	2	Renal Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Myelodysplastic Syndromehematologic_malignancy	unknown	2	Myelodysplastic Syndrome	1	Curated	chembl	graph →
→ investigated for	Sarcomacancer_family	unknown	2	Sarcoma	1	Curated	chembl	graph →
→ investigated for	Neuroblastomasubtype	unknown	2	Neuroblastoma	1	Curated	chembl	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype	unknown	2	Lung Non-Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Malignant Mesotheliomacancer_family	supports	E	Malignant Mesothelioma	1	Curated	civic	graph →
→ investigated for	Salivary Gland Neoplasmcancer_family	unknown	1	Salivary Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Plasma Cell Neoplasmhematologic_malignancy	unknown	1	Plasma Cell Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lymphoid Leukemiahematologic_malignancy	unknown	1	Lymphoid Leukemia	1	Curated	chembl	graph →
→ investigated for	Squamous Cell Carcinomahistology	unknown	1	Squamous Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Ovarian Carcinomasubtype	unknown	1	Ovarian Carcinoma	1	Curated	chembl	graph →
→ investigated for	Skin Neoplasmcancer_family	unknown	1	Skin Neoplasm	1	Curated	chembl	graph →
→ investigated for	Head and Neck Squamous Cell Carcinomasubtype	unknown	1	Head and Neck Squamous Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Oropharyngeal Neoplasmsubtype	unknown	1	Oropharyngeal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Esophageal Neoplasmcancer_family	unknown	1	Esophageal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Gliomasubtype	unknown	1	Glioma	1	Curated	chembl	graph →
→ investigated for	Liver Neoplasmsubtype	unknown	1	Liver Neoplasm	1	Curated	chembl	graph →
→ investigated for	Peritoneal Neoplasmcancer_family	unknown	1	Peritoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Fallopian Tube Neoplasmsubtype	unknown	1	Fallopian Tube Neoplasm	1	Curated	chembl	graph →
→ investigated for	Anal Neoplasmsubtype	unknown	1	Anal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Gastric Neoplasmcancer_family	unknown	1	Gastric Neoplasm	1	Curated	chembl	graph →
→ investigated for	Diffuse Intrinsic Pontine Gliomasubtype	unknown	1	Diffuse Intrinsic Pontine Glioma	1	Curated	chembl	graph →
→ investigated for	Hypopharyngeal Neoplasmsubtype	unknown	1	Hypopharyngeal Neoplasm	1	Curated	chembl	graph →
→ investigated for	T Acute Lymphoblastic Leukemiahematologic_malignancy	unknown	1	T Acute Lymphoblastic Leukemia	1	Curated	chembl	graph →
→ investigated for	Juvenile Myelomonocytic Leukemiahematologic_malignancy	unknown	1	Juvenile Myelomonocytic Leukemia	1	Curated	chembl	graph →
→ investigated for	Verrucous Carcinomahistology	unknown	1	Verrucous Carcinoma	1	Curated	chembl	graph →
→ investigated for	Medulloblastomasubtype	unknown	1	Medulloblastoma	1	Curated	chembl	graph →
→ investigated for	Oligodendrogliomasubtype	unknown	1	Oligodendroglioma	1	Curated	chembl	graph →
→ investigated for	Lung Small Cell Carcinomasubtype	unknown	1	Lung Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype	unknown	1	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Curated	chembl	graph →
→ investigated for	Burkitt Lymphomahematologic_malignancy	unknown	1	Burkitt Lymphoma	1	Curated	chembl	graph →
→ investigated for	Acute Promyelocytic Leukemiahematologic_malignancy	unknown	1	Acute Promyelocytic Leukemia	1	Curated	chembl	graph →
→ investigated for	Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy	unknown	1	Peripheral T-Cell Lymphoma, Not Otherwise Specified	1	Curated	chembl	graph →
→ investigated for	Melanomacancer_family	unknown	1	Melanoma	1	Curated	chembl	graph →
→ investigated for	Pancreatic Neoplasmsubtype	unknown	1	Pancreatic Neoplasm	1	Curated	chembl	graph →

Vorinostat investigated for …INVESTIGATED_FOR74 of 74show fewer

→ investigated for

T-Cell Non-Hodgkin Lymphomahematologic_malignancy

unknown

Curated

→ investigated for

Neoplasmcancer_family

unknown

Neoplasm

Curated

Primary Cutaneous T-Cell Non-Hodgkin Lymphoma

→ investigated for

Primary Cutaneous T-Cell Non-Hodgkin Lymphomahematologic_malignancy

unknown

Curated

→ investigated for

Malignant Colorectal Neoplasmsubtype

supports

Curated

→ investigated for

Sarcomacancer_family

supports

Curated

→ investigated for

Lung Neoplasmcancer_family

unknown

Lung Neoplasm

Curated

→ investigated for

Malignant Mesotheliomacancer_family

unknown

Malignant Mesothelioma

Curated

→ investigated for

Acute Myeloid Leukemiahematologic_malignancy

unknown

Acute Myeloid Leukemia

Curated

→ investigated for

Lymphomacancer_family

unknown

Lymphoma

Curated

→ investigated for

Multiple Myelomahematologic_malignancy

unknown

Multiple Myeloma

Curated

→ investigated for

Sarcomacancer_family

supports

Curated

→ investigated for

Uveal Melanomasubtype

supports

Uveal Melanoma

Curated

Thyroid Gland Follicular Carcinoma

→ investigated for

Thyroid Gland Follicular Carcinomacancer_family

unknown

Curated

→ investigated for

Uveal Melanomasubtype

unknown

Uveal Melanoma

Curated

→ investigated for

Bladder Neoplasmsubtype

unknown

Bladder Neoplasm

Curated

→ investigated for

Colon Neoplasmsubtype

unknown

Colon Neoplasm

Curated

Acute Biphenotypic Leukemia

→ investigated for

Acute Biphenotypic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Brain Neoplasmsubtype

unknown

Brain Neoplasm

Curated

→ investigated for

Rectal Neoplasmsubtype

unknown

Rectal Neoplasm

Curated

→ investigated for

Polycythemia Verahematologic_malignancy

unknown

Polycythemia Vera

Curated

→ investigated for

Thyroid Gland Neoplasmsubtype

unknown

Thyroid Gland Neoplasm

Curated

→ investigated for

Colorectal Neoplasmsubtype

unknown

Colorectal Neoplasm

Curated

Essential Thrombocythemia

→ investigated for

Essential Thrombocythemiahematologic_malignancy

unknown

Curated

→ investigated for

Mantle Cell Lymphomahematologic_malignancy

unknown

Mantle Cell Lymphoma

Curated

→ investigated for

Sezary Syndromehematologic_malignancy

unknown

Sezary Syndrome

Curated

→ investigated for

Non-Hodgkin Lymphomahematologic_malignancy

unknown

Non-Hodgkin Lymphoma

Curated

→ investigated for

Breast Neoplasmcancer_family

unknown

Breast Neoplasm

Curated

→ investigated for

Astrocytic Tumorsubtype

unknown

Astrocytic Tumor

Curated

→ investigated for

Prostate Neoplasmsubtype

unknown

Prostate Neoplasm

Curated

→ investigated for

Leukemiacancer_family

unknown

Leukemia

Curated

→ investigated for

Glioblastomasubtype

unknown

Glioblastoma

Curated

Acute Lymphoblastic Leukemia

→ investigated for

Acute Lymphoblastic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Hodgkin Lymphomahematologic_malignancy

unknown

Hodgkin Lymphoma

Curated

Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue

→ investigated for

Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissuehematologic_malignancy

unknown

Curated

→ investigated for

Ovarian Neoplasmsubtype

unknown

Ovarian Neoplasm

Curated

Chronic Lymphocytic Leukemia

→ investigated for

Chronic Lymphocytic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Follicular Lymphomahematologic_malignancy

unknown

Follicular Lymphoma

Curated

→ investigated for

Gliosarcomasubtype

unknown

Gliosarcoma

Curated

→ investigated for

Mycosis Fungoideshematologic_malignancy

unknown

Mycosis Fungoides

Curated

→ investigated for

Renal Cell Carcinomasubtype

unknown

Renal Cell Carcinoma

Curated

→ investigated for

Myelodysplastic Syndromehematologic_malignancy

unknown

Myelodysplastic Syndrome

Curated

→ investigated for

Sarcomacancer_family

unknown

Curated

→ investigated for

Neuroblastomasubtype

unknown

Curated

Lung Non-Small Cell Carcinoma

→ investigated for

Lung Non-Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Malignant Mesotheliomacancer_family

supports

Malignant Mesothelioma

Curated

→ investigated for

Salivary Gland Neoplasmcancer_family

unknown

Salivary Gland Neoplasm

Curated

→ investigated for

Plasma Cell Neoplasmhematologic_malignancy

unknown

Plasma Cell Neoplasm

Curated

→ investigated for

Lymphoid Leukemiahematologic_malignancy

unknown

Lymphoid Leukemia

Curated

→ investigated for

Squamous Cell Carcinomahistology

unknown

Squamous Cell Carcinoma

Curated

→ investigated for

Ovarian Carcinomasubtype

unknown

Ovarian Carcinoma

Curated

→ investigated for

Skin Neoplasmcancer_family

unknown

Skin Neoplasm

Curated

Head and Neck Squamous Cell Carcinoma

→ investigated for

Head and Neck Squamous Cell Carcinomasubtype

unknown

Curated

→ investigated for

Oropharyngeal Neoplasmsubtype

unknown

Oropharyngeal Neoplasm

Curated

→ investigated for

Esophageal Neoplasmcancer_family

unknown

Esophageal Neoplasm

Curated

→ investigated for

Gliomasubtype

unknown

Glioma

Curated

→ investigated for

Liver Neoplasmsubtype

unknown

Liver Neoplasm

Curated

→ investigated for

Peritoneal Neoplasmcancer_family

unknown

Peritoneal Neoplasm

Curated

→ investigated for

Fallopian Tube Neoplasmsubtype

unknown

Fallopian Tube Neoplasm

Curated

→ investigated for

Anal Neoplasmsubtype

unknown

Anal Neoplasm

Curated

→ investigated for

Gastric Neoplasmcancer_family

unknown

Gastric Neoplasm

Curated

Diffuse Intrinsic Pontine Glioma

→ investigated for

Diffuse Intrinsic Pontine Gliomasubtype

unknown

Curated

→ investigated for

Hypopharyngeal Neoplasmsubtype

unknown

Hypopharyngeal Neoplasm

Curated

T Acute Lymphoblastic Leukemia

→ investigated for

T Acute Lymphoblastic Leukemiahematologic_malignancy

unknown

Curated

Juvenile Myelomonocytic Leukemia

→ investigated for

Juvenile Myelomonocytic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Verrucous Carcinomahistology

unknown

Verrucous Carcinoma

Curated

→ investigated for

Medulloblastomasubtype

unknown

Medulloblastoma

Curated

→ investigated for

Oligodendrogliomasubtype

unknown

Oligodendroglioma

Curated

Lung Small Cell Carcinoma

→ investigated for

Lung Small Cell Carcinomasubtype

unknown

Curated

Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

unknown

Curated

→ investigated for

Burkitt Lymphomahematologic_malignancy

unknown

Burkitt Lymphoma

Curated

Acute Promyelocytic Leukemia

→ investigated for

Acute Promyelocytic Leukemiahematologic_malignancy

unknown

Curated

Peripheral T-Cell Lymphoma, Not Otherwise Specified

→ investigated for

Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy

unknown

Curated

→ investigated for

Melanomacancer_family

unknown

Melanoma

Curated

→ investigated for

Pancreatic Neoplasmsubtype

unknown

Pancreatic Neoplasm

Curated

Vorinostat investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 278show all (up to 200)
→ investigated in trials for	Lymphomacancer_family 19 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lymphoma	19	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Breast Neoplasm 17 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Breast Neoplasm	17	Observed	clinicaltrials	graph →
→ investigated in trials for	Multiple Myelomahematologic_malignancy 14 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Multiple Myeloma	14	Observed	clinicaltrials	graph →
→ investigated in trials for	Adult Solid Neoplasm 13 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Adult Solid Neoplasm	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Non-Small Cell Carcinomasubtype 13 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Small Cell Carcinoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Myelodysplastic Syndromehematologic_malignancy 13 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Myelodysplastic Syndrome	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Adult Acute Myeloid Leukemia 12 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Adult Acute Myeloid Leukemia	12	Observed	clinicaltrials	graph →
→ investigated in trials for	Non-Hodgkin Lymphomahematologic_malignancy 11 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Non-Hodgkin Lymphoma	11	Observed	clinicaltrials	graph →
→ investigated in trials for	Acute Myeloid Leukemiahematologic_malignancy 10 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Acute Myeloid Leukemia	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Mantle Cell Lymphomahematologic_malignancy 10 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Mantle Cell Lymphoma	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Neuroblastomasubtype 10 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Neuroblastoma	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Neoplasm 9 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Neoplasm	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Acute Lymphoblastic Leukemiahematologic_malignancy 8 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Acute Lymphoblastic Leukemia	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Acute Myeloid Leukemia with t(8;21)(q22;q22.1); RUNX1-RUNX1T1 8 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Acute Myeloid Leukemia with t(8;21)(q22;q22.1); RUNX1-RUNX1T1	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Adult Acute Myeloid Leukemia with t(16;16)(p13.1;q22); CBFB-MYH11 8 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Adult Acute Myeloid Leukemia with t(16;16)(p13.1;q22); CBFB-MYH11	8	Observed	clinicaltrials	graph →

Vorinostat investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 278show all (up to 200)

→ investigated in trials for

Lymphomacancer_family

19 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Lymphoma

Observed

Malignant Breast Neoplasm

→ investigated in trials for

17 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Breast Neoplasm

Observed

→ investigated in trials for

Multiple Myelomahematologic_malignancy

14 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Multiple Myeloma

Observed

→ investigated in trials for

Adult Solid Neoplasm

13 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Adult Solid Neoplasm

Observed

Lung Non-Small Cell Carcinoma

→ investigated in trials for

Lung Non-Small Cell Carcinomasubtype

13 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Myelodysplastic Syndromehematologic_malignancy

13 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Myelodysplastic Syndrome

Observed

Adult Acute Myeloid Leukemia

→ investigated in trials for

12 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Adult Acute Myeloid Leukemia

Observed

→ investigated in trials for

Non-Hodgkin Lymphomahematologic_malignancy

11 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Non-Hodgkin Lymphoma

Observed

→ investigated in trials for

Acute Myeloid Leukemiahematologic_malignancy

10 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Acute Myeloid Leukemia

Observed

→ investigated in trials for

Mantle Cell Lymphomahematologic_malignancy

10 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Mantle Cell Lymphoma

Observed

→ investigated in trials for

Neuroblastomasubtype

10 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Malignant Neoplasm

9 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Neoplasm

Observed

Acute Lymphoblastic Leukemia

→ investigated in trials for

Acute Lymphoblastic Leukemiahematologic_malignancy

8 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Acute Myeloid Leukemia with t(8;21)(q22;q22.1); RUNX1-RUNX1T1

→ investigated in trials for

8 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Acute Myeloid Leukemia with t(8;21)(q22;q22.1); RUNX1-RUNX1T1

Observed

Adult Acute Myeloid Leukemia with t(16;16)(p13.1;q22); CBFB-MYH11

→ investigated in trials for

8 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Adult Acute Myeloid Leukemia with t(16;16)(p13.1;q22); CBFB-MYH11

Observed

Vorinostat studied in …STUDIED_INderived10 of 214show all (up to 200)
→ studied in	NCT00972478Phase 1/Phase 2 · active not recruiting Vorinostat, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma · 214 trials list this drug (22 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →
→ studied in	NCT01522976Phase 2 · active not recruiting Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia · 214 trials list this drug (22 active)	—	—	Myelodysplastic Syndrome,Chronic Myelomonocytic Leukemia,Myelodysplastic Syndrome with Excess Blasts+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT02559778Phase 2 · recruiting Pediatric Precision Laboratory Advanced Neuroblastoma Therapy · 214 trials list this drug (22 active)	—	—	Neuroblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03150329Phase 1 · active not recruiting Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL. · 214 trials list this drug (22 active)	—	—	B-Cell Malignant Neoplasm,Classic Hodgkin Lymphoma,Transformed Non-Hodgkin Lymphoma+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT07261241Phase 2 · not yet recruiting NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + Dinutuximab · 214 trials list this drug (22 active)	—	—	Neuroblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00268385Phase 1 · active not recruiting Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas · 214 trials list this drug (22 active)	—	—	Adult Mixed Glioma,Adult Anaplastic Astrocytoma,Adult Anaplastic Oligodendroglioma+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT00336063Phase 1 · active not recruiting Vorinostat and Azacitidine in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer or Nasal Natural Killer T-Cell Lymphoma · 214 trials list this drug (22 active)	—	—	Nasopharyngeal Undifferentiated Carcinoma,Adult Nasal Type Extranodal NK/T-Cell Lymphoma,Nasopharyngeal Keratinizing Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00392353Phase 1/Phase 2 · active not recruiting Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia · 214 trials list this drug (22 active)	—	—	Myelodysplastic Syndrome,Myelodysplastic Syndrome with Ring Sideroblasts,Acute Erythroid Leukemia+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT06145633Phase 2 · recruiting Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer · 214 trials list this drug (22 active)	—	—	Prostate Adenocarcinoma,Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03259503Phase 1 · completed Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant · 214 trials list this drug (22 active)	—	—	Hodgkin Lymphoma,T-Cell Non-Hodgkin Lymphoma,Diffuse Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →

Vorinostat studied in …STUDIED_INderived10 of 214show all (up to 200)

→ studied in

NCT00972478Phase 1/Phase 2 · active not recruiting

Vorinostat, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma · 214 trials list this drug (22 active)

—

not mapped

Observed

Myelodysplastic Syndrome,Chronic Myelomonocytic Leukemia,Myelodysplastic Syndrome with Excess Blasts+2

→ studied in

NCT01522976Phase 2 · active not recruiting

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia · 214 trials list this drug (22 active)

—

Observed

→ studied in

NCT02559778Phase 2 · recruiting

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy · 214 trials list this drug (22 active)

—

Observed

B-Cell Malignant Neoplasm,Classic Hodgkin Lymphoma,Transformed Non-Hodgkin Lymphoma+2

→ studied in

NCT03150329Phase 1 · active not recruiting

Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL. · 214 trials list this drug (22 active)

—

Observed

→ studied in

NCT07261241Phase 2 · not yet recruiting

NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + Dinutuximab · 214 trials list this drug (22 active)

—

Observed

Adult Mixed Glioma,Adult Anaplastic Astrocytoma,Adult Anaplastic Oligodendroglioma+2

→ studied in

NCT00268385Phase 1 · active not recruiting

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas · 214 trials list this drug (22 active)

—

Observed

Nasopharyngeal Undifferentiated Carcinoma,Adult Nasal Type Extranodal NK/T-Cell Lymphoma,Nasopharyngeal Keratinizing Squamous Cell Carcinoma

→ studied in

NCT00336063Phase 1 · active not recruiting

Vorinostat and Azacitidine in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer or Nasal Natural Killer T-Cell Lymphoma · 214 trials list this drug (22 active)

—

Observed

Myelodysplastic Syndrome,Myelodysplastic Syndrome with Ring Sideroblasts,Acute Erythroid Leukemia+2

→ studied in

NCT00392353Phase 1/Phase 2 · active not recruiting

Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia · 214 trials list this drug (22 active)

—

Observed

Prostate Adenocarcinoma,Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma

→ studied in

NCT06145633Phase 2 · recruiting

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer · 214 trials list this drug (22 active)

—

Observed

Hodgkin Lymphoma,T-Cell Non-Hodgkin Lymphoma,Diffuse Large B-Cell Lymphoma

→ studied in

NCT03259503Phase 1 · completed

Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant · 214 trials list this drug (22 active)

—

Observed