Nivolumab

← predicts response to

DNMT3A Mutationother

resistance

Curated

← predicts response to

KRAS Mutationother

sensitivity

Curated

← predicts response to

HLA-DRA EXPRESSIONexpression

sensitivity

Cutaneous Melanoma

Curated

← predicts response to

MSH2 Lossdeletion_cna

sensitivity

Curated

← predicts response to

MLH1 Lossdeletion_cna

sensitivity

Curated

← predicts response to

STK11 Mutationother

resistance

Lung Adenocarcinoma

Curated

← predicts response to

PMS2 K706FS*19indel

sensitivity

Glioblastoma

Curated

Nivolumab targets …TARGETS1 of 1
→ targets	PDCD1	—	INHIBITOR	—	1	Curated	chembl	graph →

Nivolumab targets …TARGETS1 of 1

→ targets

PDCD1

—

INHIBITOR

—

Curated

Nivolumab investigated for …INVESTIGATED_FOR100 of 100show fewer
→ investigated for	Lung Non-Small Cell Carcinomasubtype 4 source records aggregated	supports	B	Lung Non-Small Cell Carcinoma	4	Curated	civic	graph →
→ investigated for	Malignant Neoplasmcancer_family 3 source records aggregated	supports	B	Malignant Neoplasm	3	Curated	civic	graph →
→ investigated for	Cutaneous Melanomacancer	supports	B	Cutaneous Melanoma	1	Curated	civic	graph →
→ investigated for	Lung Adenocarcinomasubtype	supports	B	Lung Adenocarcinoma	1	Curated	civic	graph →
→ investigated for	Melanomacancer_family	supports	B	Melanoma	1	Curated	civic	graph →
→ investigated for	Transitional Cell Carcinomahistology	unknown	4	Transitional Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Head and Neck Squamous Cell Carcinomasubtype	unknown	4	Head and Neck Squamous Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Colorectal Neoplasmsubtype	unknown	4	Colorectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Hodgkin Lymphomahematologic_malignancy	unknown	4	Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Neoplasmcancer_family	unknown	4	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Renal Cell Carcinomasubtype	unknown	4	Renal Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Melanomacancer_family	unknown	4	Melanoma	1	Curated	chembl	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype	unknown	4	Lung Non-Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Glioblastomasubtype	supports	C	Glioblastoma	1	Curated	civic	graph →
→ investigated for	Skin Neoplasmcancer_family	unknown	3	Skin Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lung Neoplasmcancer_family	unknown	3	Lung Neoplasm	1	Curated	chembl	graph →
→ investigated for	Kidney Neoplasmsubtype	unknown	3	Kidney Neoplasm	1	Curated	chembl	graph →
→ investigated for	Gastric Neoplasmcancer_family	unknown	3	Gastric Neoplasm	1	Curated	chembl	graph →
→ investigated for	Bladder Neoplasmsubtype	unknown	3	Bladder Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lung Adenocarcinomasubtype	unknown	3	Lung Adenocarcinoma	1	Curated	chembl	graph →
→ investigated for	Head and Neck Neoplasmcancer_family	unknown	3	Head and Neck Neoplasm	1	Curated	chembl	graph →
→ investigated for	Multiple Myelomahematologic_malignancy	unknown	3	Multiple Myeloma	1	Curated	chembl	graph →
→ investigated for	Adenocarcinomahistology	unknown	3	Adenocarcinoma	1	Curated	chembl	graph →
→ investigated for	Esophageal Neoplasmcancer_family	unknown	3	Esophageal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Hepatocellular Carcinomasubtype	unknown	3	Hepatocellular Carcinoma	1	Curated	chembl	graph →
→ investigated for	Glioblastomasubtype	unknown	3	Glioblastoma	1	Curated	chembl	graph →
→ investigated for	Breast Neoplasmcancer_family	unknown	3	Breast Neoplasm	1	Curated	chembl	graph →
→ investigated for	Sarcomacancer_family	unknown	3	Sarcoma	1	Curated	chembl	graph →
→ investigated for	Brain Neoplasmsubtype	unknown	3	Brain Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lymphomacancer_family	unknown	3	Lymphoma	1	Curated	chembl	graph →
→ investigated for	Squamous Cell Carcinomahistology	unknown	3	Squamous Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Nasopharyngeal Carcinomasubtype	unknown	2	Nasopharyngeal Carcinoma	1	Curated	chembl	graph →
→ investigated for	Neuroendocrine Tumorsubtype	unknown	2	Neuroendocrine Tumor	1	Curated	chembl	graph →
→ investigated for	Malignant Mesotheliomacancer_family	unknown	2	Malignant Mesothelioma	1	Curated	chembl	graph →
→ investigated for	Paragangliomasubtype	unknown	2	Paraganglioma	1	Curated	chembl	graph →
→ investigated for	Uveal Melanomasubtype	unknown	2	Uveal Melanoma	1	Curated	chembl	graph →
→ investigated for	Chordomacancer_family	unknown	2	Chordoma	1	Curated	chembl	graph →
→ investigated for	Gastrointestinal Stromal Tumorsubtype	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
→ investigated for	Craniopharyngiomacancer	unknown	2	Craniopharyngioma	1	Curated	chembl	graph →
→ investigated for	Carcinosarcomasubtype	unknown	2	Carcinosarcoma	1	Curated	chembl	graph →
→ investigated for	Anaplastic Large Cell Lymphomahematologic_malignancy	unknown	2	Anaplastic Large Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Small Cell Neuroendocrine Carcinomasubtype	unknown	2	Small Cell Neuroendocrine Carcinoma	1	Curated	chembl	graph →
→ investigated for	Leiomyosarcomasubtype	unknown	2	Leiomyosarcoma	1	Curated	chembl	graph →
→ investigated for	Cholangiocarcinomasubtype	unknown	2	Cholangiocarcinoma	1	Curated	chembl	graph →
→ investigated for	Meningiomasubtype	unknown	2	Meningioma	1	Curated	chembl	graph →
→ investigated for	Follicular Lymphomahematologic_malignancy	unknown	2	Follicular Lymphoma	1	Curated	chembl	graph →
→ investigated for	Pituitary Gland Neoplasmcancer_family	unknown	2	Pituitary Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Salivary Gland Neoplasmcancer_family	unknown	2	Salivary Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Liver Neoplasmsubtype	unknown	2	Liver Neoplasm	1	Curated	chembl	graph →
→ investigated for	Neuroendocrine Carcinomasubtype	unknown	2	Neuroendocrine Carcinoma	1	Curated	chembl	graph →
→ investigated for	Peritoneal Neoplasmcancer_family	unknown	2	Peritoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Oropharyngeal Neoplasmsubtype	unknown	2	Oropharyngeal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Undifferentiated Pleomorphic Sarcomasubtype	unknown	2	Undifferentiated Pleomorphic Sarcoma	1	Curated	chembl	graph →
→ investigated for	Endometrial Neoplasmsubtype	unknown	2	Endometrial Neoplasm	1	Curated	chembl	graph →
→ investigated for	Basal Cell Carcinomahistology	unknown	2	Basal Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Liposarcomasubtype	unknown	2	Liposarcoma	1	Curated	chembl	graph →
→ investigated for	Osteosarcomasubtype	unknown	2	Osteosarcoma	1	Curated	chembl	graph →
→ investigated for	Colon Neoplasmsubtype	unknown	2	Colon Neoplasm	1	Curated	chembl	graph →
→ investigated for	Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy	unknown	2	Peripheral T-Cell Lymphoma, Not Otherwise Specified	1	Curated	chembl	graph →
→ investigated for	Gliosarcomasubtype	unknown	2	Gliosarcoma	1	Curated	chembl	graph →
→ investigated for	Merkel Cell Carcinomasubtype	unknown	2	Merkel Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Adrenal Cortical Neoplasmsubtype	unknown	2	Adrenal Cortical Neoplasm	1	Curated	chembl	graph →
→ investigated for	Breast Inflammatory Carcinomasubtype	unknown	2	Breast Inflammatory Carcinoma	1	Curated	chembl	graph →
→ investigated for	Rectal Neoplasmsubtype	unknown	2	Rectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Nasopharyngeal Neoplasmsubtype	unknown	2	Nasopharyngeal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Large Cell Carcinomahistology	unknown	2	Large Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Hematopoietic and Lymphoid Cell Neoplasmcancer_family	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
→ investigated for	Thyroid Gland Neoplasmsubtype	unknown	2	Thyroid Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Ovarian Neoplasmsubtype	unknown	2	Ovarian Neoplasm	1	Curated	chembl	graph →
→ investigated for	Prostate Neoplasmsubtype	unknown	2	Prostate Neoplasm	1	Curated	chembl	graph →
→ investigated for	Cervical Neoplasmsubtype	unknown	2	Cervical Neoplasm	1	Curated	chembl	graph →
→ investigated for	Oligodendrogliomasubtype	unknown	2	Oligodendroglioma	1	Curated	chembl	graph →
→ investigated for	Leukemiacancer_family	unknown	2	Leukemia	1	Curated	chembl	graph →
→ investigated for	Kaposi Sarcomacancer	unknown	2	Kaposi Sarcoma	1	Curated	chembl	graph →
→ investigated for	Carcinomacancer_family	unknown	2	Carcinoma	1	Curated	chembl	graph →
→ investigated for	Myelodysplastic Syndromehematologic_malignancy	unknown	2	Myelodysplastic Syndrome	1	Curated	chembl	graph →
→ investigated for	Chronic Lymphocytic Leukemiahematologic_malignancy	unknown	2	Chronic Lymphocytic Leukemia	1	Curated	chembl	graph →
→ investigated for	Gliomasubtype	unknown	2	Glioma	1	Curated	chembl	graph →
→ investigated for	Pancreatic Neoplasmsubtype	unknown	2	Pancreatic Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lung Small Cell Carcinomasubtype	unknown	2	Lung Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Acute Myeloid Leukemiahematologic_malignancy	unknown	2	Acute Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Non-Hodgkin Lymphomahematologic_malignancy	unknown	2	Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Myeloid Leukemiahematologic_malignancy	unknown	1	Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Primary Cutaneous T-Cell Non-Hodgkin Lymphomahematologic_malignancy	unknown	1	Primary Cutaneous T-Cell Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Rhabdomyosarcomasubtype	unknown	1	Rhabdomyosarcoma	1	Curated	chembl	graph →
→ investigated for	Ewing Sarcomasubtype	unknown	1	Ewing Sarcoma	1	Curated	chembl	graph →
→ investigated for	Synovial Sarcomasubtype	unknown	1	Synovial Sarcoma	1	Curated	chembl	graph →
→ investigated for	Female Reproductive System Neoplasmsubtype	unknown	1	Female Reproductive System Neoplasm	1	Curated	chembl	graph →
→ investigated for	Nerve Sheath Neoplasmcancer_family	unknown	1	Nerve Sheath Neoplasm	1	Curated	chembl	graph →
→ investigated for	Sezary Syndromehematologic_malignancy	unknown	1	Sezary Syndrome	1	Curated	chembl	graph →
→ investigated for	T-Cell Non-Hodgkin Lymphomahematologic_malignancy	unknown	1	T-Cell Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Diffuse Intrinsic Pontine Gliomasubtype	unknown	1	Diffuse Intrinsic Pontine Glioma	1	Curated	chembl	graph →
→ investigated for	Fallopian Tube Neoplasmsubtype	unknown	1	Fallopian Tube Neoplasm	1	Curated	chembl	graph →
→ investigated for	Mycosis Fungoideshematologic_malignancy	unknown	1	Mycosis Fungoides	1	Curated	chembl	graph →
→ investigated for	Retroperitoneal Neoplasmcancer_family	unknown	1	Retroperitoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Mantle Cell Lymphomahematologic_malignancy	unknown	1	Mantle Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Triple-Negative Breast Carcinomamolecular_subtype	unknown	1	Triple-Negative Breast Carcinoma	1	Curated	chembl	graph →
→ investigated for	Neuroblastomasubtype	unknown	1	Neuroblastoma	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype	unknown	1	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Curated	chembl	graph →
→ investigated for	Acute Lymphoblastic Leukemiahematologic_malignancy	unknown	1	Acute Lymphoblastic Leukemia	1	Curated	chembl	graph →

Nivolumab investigated for …INVESTIGATED_FOR100 of 100show fewer

→ investigated for

Lung Non-Small Cell Carcinomasubtype

4 source records aggregated

supports

Curated

→ investigated for

Malignant Neoplasmcancer_family

3 source records aggregated

supports

Curated

→ investigated for

Cutaneous Melanomacancer

supports

Cutaneous Melanoma

Curated

→ investigated for

Lung Adenocarcinomasubtype

supports

Lung Adenocarcinoma

Curated

→ investigated for

Melanomacancer_family

supports

Melanoma

Curated

Transitional Cell Carcinoma

→ investigated for

Transitional Cell Carcinomahistology

unknown

Curated

Head and Neck Squamous Cell Carcinoma

→ investigated for

Head and Neck Squamous Cell Carcinomasubtype

unknown

Curated

→ investigated for

Colorectal Neoplasmsubtype

unknown

Colorectal Neoplasm

Curated

→ investigated for

Hodgkin Lymphomahematologic_malignancy

unknown

Hodgkin Lymphoma

Curated

→ investigated for

Neoplasmcancer_family

unknown

Neoplasm

Curated

→ investigated for

Renal Cell Carcinomasubtype

unknown

Renal Cell Carcinoma

Curated

→ investigated for

Melanomacancer_family

unknown

Melanoma

Curated

→ investigated for

Lung Non-Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Glioblastomasubtype

supports

Glioblastoma

Curated

→ investigated for

Skin Neoplasmcancer_family

unknown

Skin Neoplasm

Curated

→ investigated for

Lung Neoplasmcancer_family

unknown

Lung Neoplasm

Curated

→ investigated for

Kidney Neoplasmsubtype

unknown

Kidney Neoplasm

Curated

→ investigated for

Gastric Neoplasmcancer_family

unknown

Gastric Neoplasm

Curated

→ investigated for

Bladder Neoplasmsubtype

unknown

Bladder Neoplasm

Curated

→ investigated for

Lung Adenocarcinomasubtype

unknown

Lung Adenocarcinoma

Curated

→ investigated for

Head and Neck Neoplasmcancer_family

unknown

Head and Neck Neoplasm

Curated

→ investigated for

Multiple Myelomahematologic_malignancy

unknown

Multiple Myeloma

Curated

→ investigated for

Adenocarcinomahistology

unknown

Adenocarcinoma

Curated

→ investigated for

Esophageal Neoplasmcancer_family

unknown

Esophageal Neoplasm

Curated

→ investigated for

Hepatocellular Carcinomasubtype

unknown

Hepatocellular Carcinoma

Curated

→ investigated for

Glioblastomasubtype

unknown

Glioblastoma

Curated

→ investigated for

Breast Neoplasmcancer_family

unknown

Breast Neoplasm

Curated

→ investigated for

Sarcomacancer_family

unknown

Sarcoma

Curated

→ investigated for

Brain Neoplasmsubtype

unknown

Brain Neoplasm

Curated

→ investigated for

Lymphomacancer_family

unknown

Lymphoma

Curated

→ investigated for

Squamous Cell Carcinomahistology

unknown

Squamous Cell Carcinoma

Curated

→ investigated for

Nasopharyngeal Carcinomasubtype

unknown

Nasopharyngeal Carcinoma

Curated

→ investigated for

Neuroendocrine Tumorsubtype

unknown

Neuroendocrine Tumor

Curated

→ investigated for

Malignant Mesotheliomacancer_family

unknown

Malignant Mesothelioma

Curated

→ investigated for

Paragangliomasubtype

unknown

Paraganglioma

Curated

→ investigated for

Uveal Melanomasubtype

unknown

Uveal Melanoma

Curated

→ investigated for

Chordomacancer_family

unknown

Chordoma

Curated

Gastrointestinal Stromal Tumor

→ investigated for

Gastrointestinal Stromal Tumorsubtype

unknown

Curated

→ investigated for

Craniopharyngiomacancer

unknown

Craniopharyngioma

Curated

→ investigated for

Carcinosarcomasubtype

unknown

Carcinosarcoma

Curated

Anaplastic Large Cell Lymphoma

→ investigated for

Anaplastic Large Cell Lymphomahematologic_malignancy

unknown

Curated

Small Cell Neuroendocrine Carcinoma

→ investigated for

Small Cell Neuroendocrine Carcinomasubtype

unknown

Curated

→ investigated for

Leiomyosarcomasubtype

unknown

Leiomyosarcoma

Curated

→ investigated for

Cholangiocarcinomasubtype

unknown

Cholangiocarcinoma

Curated

→ investigated for

Meningiomasubtype

unknown

Meningioma

Curated

→ investigated for

Follicular Lymphomahematologic_malignancy

unknown

Follicular Lymphoma

Curated

→ investigated for

Pituitary Gland Neoplasmcancer_family

unknown

Pituitary Gland Neoplasm

Curated

→ investigated for

Salivary Gland Neoplasmcancer_family

unknown

Salivary Gland Neoplasm

Curated

→ investigated for

Liver Neoplasmsubtype

unknown

Liver Neoplasm

Curated

→ investigated for

Neuroendocrine Carcinomasubtype

unknown

Neuroendocrine Carcinoma

Curated

→ investigated for

Peritoneal Neoplasmcancer_family

unknown

Peritoneal Neoplasm

Curated

→ investigated for

Oropharyngeal Neoplasmsubtype

unknown

Oropharyngeal Neoplasm

Curated

Undifferentiated Pleomorphic Sarcoma

→ investigated for

Undifferentiated Pleomorphic Sarcomasubtype

unknown

Curated

→ investigated for

Endometrial Neoplasmsubtype

unknown

Endometrial Neoplasm

Curated

→ investigated for

Basal Cell Carcinomahistology

unknown

Basal Cell Carcinoma

Curated

→ investigated for

Liposarcomasubtype

unknown

Liposarcoma

Curated

→ investigated for

Osteosarcomasubtype

unknown

Osteosarcoma

Curated

→ investigated for

Colon Neoplasmsubtype

unknown

Colon Neoplasm

Curated

Peripheral T-Cell Lymphoma, Not Otherwise Specified

→ investigated for

Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy

unknown

Curated

→ investigated for

Gliosarcomasubtype

unknown

Gliosarcoma

Curated

→ investigated for

Merkel Cell Carcinomasubtype

unknown

Merkel Cell Carcinoma

Curated

Adrenal Cortical Neoplasm

→ investigated for

Adrenal Cortical Neoplasmsubtype

unknown

Curated

Breast Inflammatory Carcinoma

→ investigated for

Breast Inflammatory Carcinomasubtype

unknown

Curated

→ investigated for

Rectal Neoplasmsubtype

unknown

Rectal Neoplasm

Curated

→ investigated for

Nasopharyngeal Neoplasmsubtype

unknown

Nasopharyngeal Neoplasm

Curated

→ investigated for

Large Cell Carcinomahistology

unknown

Large Cell Carcinoma

Curated

Hematopoietic and Lymphoid Cell Neoplasm

→ investigated for

Hematopoietic and Lymphoid Cell Neoplasmcancer_family

unknown

Curated

→ investigated for

Thyroid Gland Neoplasmsubtype

unknown

Thyroid Gland Neoplasm

Curated

→ investigated for

Ovarian Neoplasmsubtype

unknown

Ovarian Neoplasm

Curated

→ investigated for

Prostate Neoplasmsubtype

unknown

Prostate Neoplasm

Curated

→ investigated for

Cervical Neoplasmsubtype

unknown

Cervical Neoplasm

Curated

→ investigated for

Oligodendrogliomasubtype

unknown

Oligodendroglioma

Curated

→ investigated for

Leukemiacancer_family

unknown

Leukemia

Curated

→ investigated for

Kaposi Sarcomacancer

unknown

Kaposi Sarcoma

Curated

→ investigated for

Carcinomacancer_family

unknown

Carcinoma

Curated

→ investigated for

Myelodysplastic Syndromehematologic_malignancy

unknown

Myelodysplastic Syndrome

Curated

Chronic Lymphocytic Leukemia

→ investigated for

Chronic Lymphocytic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Gliomasubtype

unknown

Glioma

Curated

→ investigated for

Pancreatic Neoplasmsubtype

unknown

Pancreatic Neoplasm

Curated

Lung Small Cell Carcinoma

→ investigated for

Lung Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Acute Myeloid Leukemiahematologic_malignancy

unknown

Acute Myeloid Leukemia

Curated

→ investigated for

Non-Hodgkin Lymphomahematologic_malignancy

unknown

Non-Hodgkin Lymphoma

Curated

→ investigated for

Myeloid Leukemiahematologic_malignancy

unknown

Myeloid Leukemia

Curated

Primary Cutaneous T-Cell Non-Hodgkin Lymphoma

→ investigated for

Primary Cutaneous T-Cell Non-Hodgkin Lymphomahematologic_malignancy

unknown

Curated

→ investigated for

Rhabdomyosarcomasubtype

unknown

Rhabdomyosarcoma

Curated

→ investigated for

Ewing Sarcomasubtype

unknown

Ewing Sarcoma

Curated

→ investigated for

Synovial Sarcomasubtype

unknown

Synovial Sarcoma

Curated

Female Reproductive System Neoplasm

→ investigated for

Female Reproductive System Neoplasmsubtype

unknown

Curated

→ investigated for

Nerve Sheath Neoplasmcancer_family

unknown

Nerve Sheath Neoplasm

Curated

→ investigated for

Sezary Syndromehematologic_malignancy

unknown

Sezary Syndrome

Curated

T-Cell Non-Hodgkin Lymphoma

→ investigated for

T-Cell Non-Hodgkin Lymphomahematologic_malignancy

unknown

Curated

Diffuse Intrinsic Pontine Glioma

→ investigated for

Diffuse Intrinsic Pontine Gliomasubtype

unknown

Curated

→ investigated for

Fallopian Tube Neoplasmsubtype

unknown

Fallopian Tube Neoplasm

Curated

→ investigated for

Mycosis Fungoideshematologic_malignancy

unknown

Mycosis Fungoides

Curated

→ investigated for

Retroperitoneal Neoplasmcancer_family

unknown

Retroperitoneal Neoplasm

Curated

→ investigated for

Mantle Cell Lymphomahematologic_malignancy

unknown

Mantle Cell Lymphoma

Curated

Triple-Negative Breast Carcinoma

→ investigated for

Triple-Negative Breast Carcinomamolecular_subtype

unknown

Curated

→ investigated for

Neuroblastomasubtype

unknown

Neuroblastoma

Curated

Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

unknown

Curated

Acute Lymphoblastic Leukemia

→ investigated for

Acute Lymphoblastic Leukemiahematologic_malignancy

unknown

Curated

Nivolumab investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 637show all (up to 200)
→ investigated in trials for	Melanomacancer_family 202 trials (70 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Melanoma	202	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Non-Small Cell Carcinomasubtype 178 trials (65 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Small Cell Carcinoma	178	Observed	clinicaltrials	graph →
→ investigated in trials for	Renal Cell Carcinomasubtype 102 trials (44 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Renal Cell Carcinoma	102	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Neoplasmcancer_family 76 trials (22 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Neoplasm	76	Observed	clinicaltrials	graph →
→ investigated in trials for	Solid Neoplasm 70 trials (21 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Solid Neoplasm	70	Observed	clinicaltrials	graph →
→ investigated in trials for	Hepatocellular Carcinomasubtype 65 trials (18 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Hepatocellular Carcinoma	65	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Colorectal Neoplasmsubtype 56 trials (23 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Colorectal Neoplasm	56	Observed	clinicaltrials	graph →
→ investigated in trials for	Head and Neck Squamous Cell Carcinomasubtype 52 trials (18 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Head and Neck Squamous Cell Carcinoma	52	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Lung Neoplasm 52 trials (23 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Lung Neoplasm	52	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Gastric Neoplasm 42 trials (17 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Gastric Neoplasm	42	Observed	clinicaltrials	graph →
→ investigated in trials for	Hodgkin Lymphomahematologic_malignancy 38 trials (16 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Hodgkin Lymphoma	38	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Pancreatic Neoplasm 37 trials (12 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Pancreatic Neoplasm	37	Observed	clinicaltrials	graph →
→ investigated in trials for	Clear Cell Renal Cell Carcinoma 33 trials (20 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Clear Cell Renal Cell Carcinoma	33	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Solid Neoplasm 32 trials (14 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Solid Neoplasm	32	Observed	clinicaltrials	graph →
→ investigated in trials for	Cutaneous Melanomacancer 30 trials (16 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Cutaneous Melanoma	30	Observed	clinicaltrials	graph →

Nivolumab investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 637show all (up to 200)

→ investigated in trials for

Melanomacancer_family

202 trials (70 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Melanoma

202

Observed

→ investigated in trials for

Lung Non-Small Cell Carcinomasubtype

178 trials (65 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

178

Observed

→ investigated in trials for

Renal Cell Carcinomasubtype

102 trials (44 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Renal Cell Carcinoma

102

Observed

→ investigated in trials for

Malignant Neoplasmcancer_family

76 trials (22 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Solid Neoplasm

70 trials (21 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Solid Neoplasm

Observed

→ investigated in trials for

Hepatocellular Carcinomasubtype

65 trials (18 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Hepatocellular Carcinoma

Observed

Malignant Colorectal Neoplasm

→ investigated in trials for

Malignant Colorectal Neoplasmsubtype

56 trials (23 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Head and Neck Squamous Cell Carcinoma

→ investigated in trials for

Head and Neck Squamous Cell Carcinomasubtype

52 trials (18 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Malignant Lung Neoplasm

52 trials (23 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Lung Neoplasm

Observed

Malignant Gastric Neoplasm

→ investigated in trials for

42 trials (17 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Gastric Neoplasm

Observed

→ investigated in trials for

Hodgkin Lymphomahematologic_malignancy

38 trials (16 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Hodgkin Lymphoma

Observed

Malignant Pancreatic Neoplasm

→ investigated in trials for

37 trials (12 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Pancreatic Neoplasm

Observed

Clear Cell Renal Cell Carcinoma

→ investigated in trials for

33 trials (20 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Clear Cell Renal Cell Carcinoma

Observed

→ investigated in trials for

Malignant Solid Neoplasm

32 trials (14 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Solid Neoplasm

Observed

→ investigated in trials for

Cutaneous Melanomacancer

30 trials (16 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Cutaneous Melanoma

Observed

Nivolumab studied in …STUDIED_INderived10 of 1,426show all (up to 200)
→ studied in	NCT01896999Phase 1/Phase 2 · active not recruiting Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma · 1,426 trials list this drug (493 active)	—	—	Classic Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02465060Phase 2 · active not recruiting Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · 1,426 trials list this drug (493 active)	—	—	Hematopoietic and Lymphoid Cell Neoplasm,Lymphoma,Malignant Solid Neoplasm+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT02595944Phase 3 · active not recruiting Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial) · 1,426 trials list this drug (493 active)	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03707808Phase 1/Phase 2 · active not recruiting Intratumoral Injection of Autologous CD1c (BDCA-1)+ myDC, AS01B, and Ipilimumab Plus Systemic Nivolumab · 1,426 trials list this drug (493 active)	—	—	Solid Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT03811015Phase 3 · active not recruiting Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer · 1,426 trials list this drug (493 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →
→ studied in	NCT03866382Phase 2 · recruiting Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · 1,426 trials list this drug (493 active)	—	—	Malignant Genitourinary System Neoplasm,Large Cell Neuroendocrine Carcinoma,Sarcomatoid Renal Cell Carcinoma+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT04310007Phase 2 · active not recruiting Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer · 1,426 trials list this drug (493 active)	—	—	Malignant Lung Neoplasm,Lung Non-Squamous Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04396821Phase 1/Phase 2 · active not recruiting A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors · 1,426 trials list this drug (493 active)	—	—	Malignant Neoplasm,Malignant Gastric Neoplasm,Malignant Pancreatic Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT04495296Phase 1/Phase 2 · active not recruiting A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors · 1,426 trials list this drug (493 active)	—	—	Malignant Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT04751370Phase 2 · active not recruiting Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer · 1,426 trials list this drug (493 active)	—	—	Malignant Rectal Neoplasm,Rectal Adenocarcinoma	1	Observed	clinicaltrials	graph →

Nivolumab studied in …STUDIED_INderived10 of 1,426show all (up to 200)

→ studied in

NCT01896999Phase 1/Phase 2 · active not recruiting

Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma · 1,426 trials list this drug (493 active)

—

Classic Hodgkin Lymphoma

Observed

Hematopoietic and Lymphoid Cell Neoplasm,Lymphoma,Malignant Solid Neoplasm+2

→ studied in

NCT02465060Phase 2 · active not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · 1,426 trials list this drug (493 active)

—

Observed

→ studied in

NCT02595944Phase 3 · active not recruiting

Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial) · 1,426 trials list this drug (493 active)

—

Observed

→ studied in

NCT03707808Phase 1/Phase 2 · active not recruiting

Intratumoral Injection of Autologous CD1c (BDCA-1)+ myDC, AS01B, and Ipilimumab Plus Systemic Nivolumab · 1,426 trials list this drug (493 active)

—

Solid Neoplasm

Observed

→ studied in

NCT03811015Phase 3 · active not recruiting

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer · 1,426 trials list this drug (493 active)

—

not mapped

Observed

Malignant Genitourinary System Neoplasm,Large Cell Neuroendocrine Carcinoma,Sarcomatoid Renal Cell Carcinoma+2

→ studied in

NCT03866382Phase 2 · recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · 1,426 trials list this drug (493 active)

—

Observed

Malignant Lung Neoplasm,Lung Non-Squamous Non-Small Cell Carcinoma

→ studied in

NCT04310007Phase 2 · active not recruiting

Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer · 1,426 trials list this drug (493 active)

—

Observed

Malignant Neoplasm,Malignant Gastric Neoplasm,Malignant Pancreatic Neoplasm

→ studied in

NCT04396821Phase 1/Phase 2 · active not recruiting

A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors · 1,426 trials list this drug (493 active)

—

Observed

→ studied in

NCT04495296Phase 1/Phase 2 · active not recruiting

A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors · 1,426 trials list this drug (493 active)

—

Observed

Malignant Rectal Neoplasm,Rectal Adenocarcinoma

→ studied in

NCT04751370Phase 2 · active not recruiting

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer · 1,426 trials list this drug (493 active)

—

Observed