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Neuroendocrine Carcinoma · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Endocrine Neoplasm
Neuroendocrine Neoplasm
Neuroendocrine Carcinoma

Subtype

Neuroendocrine Carcinoma

CI-CAN-00001275NECExplore in graph →

515 active trials12 approved drugs28 evidence items

NCIt: C3773
OncoTree: NECNOS
MeSH: D018278

Overview
Statistics
Survival
Genomics4
Variants & evidence28
Drugs16
Trials1533
Research
Rankings
Sources & provenance

Data completeness5 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

An aggressive carcinoma composed of malignant cells that exhibit neuroendocrine differentiation. It is classified as small cell or large cell neuroendocrine carcinoma.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Endocrine CarcinomaSubtype
Neuroendocrine NeoplasmCancer Family

oncotree

Carcinoma of Unknown PrimaryHistology

Children (4)

ncit

Extrapulmonary Neuroendocrine Carcinoma10 sub
Large Cell Neuroendocrine Carcinoma2 sub
Lung Neuroendocrine Carcinoma3 sub
Small Cell Neuroendocrine Carcinoma2 sub

171 descendants in total; counters on this page aggregate over all of them.

Anatomy

Anatomical sites

EndocrineC3010

Record

Identity

CancerIndex ID: CI-CAN-00001275
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 4
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

1,533 / 515

Publications (all / 5y)

14,531 / 3,283

Evidence items

28

Genes / variants

44 / 17

Drugs (any / approved)

16 / 12

Genomic cohorts

4

Epidemiology / survival obs.

0 / 0

Data updated 15 minutes agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (7)

Carcinoma, Neuroendocrinemesh_heading · MeSH
High-Grade Neuroendocrine Carcinomasynonym · NCIt
Malignant Poorly Differentiated Epithelial Neuroendocrine Neoplasmsynonym · NCIt
Malignant poorly differentiated neuroendocrine tumorssynonym · NCIt
Neuroendocrine Cancersynonym · NCIt
Neuroendocrine Carcinoma, NOSsynonym · OncoTree
Poorly Differentiated Epithelial Neuroendocrine Neoplasmsynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

No registry-level ancestor: burden figures are published for the mutually exclusive top-level site groups only, and this entity does not descend from one. Global figures (IARC / GLOBOCAN) stay under license review and SEER awaits credentials.

Active trials515countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #75 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials261countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #80 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items28countaccepted CIViC items · entity + descendantscivicComputedrank #111 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months477countPubMed records · stored query · 12-month windowpubmedComputedrank #148 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts4countopen GDC projects · entity + descendantsgdcComputedrank #172 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 15 minutes agoSource updated unknownregistry figures: none · counters aggregate over descendants