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Large Cell Carcinoma · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Malignant Neoplasm
Carcinoma
Large Cell Carcinoma

Histology

Large Cell Carcinoma

CI-CAN-00001061Explore in graph →

47 active trials2 approved drugs5 evidence items

NCIt: C3780
MeSH: D018287

Overview
Statistics
Survival
Genomics
Variants & evidence5
Drugs6
Trials159
Research
Rankings
Sources & provenance

Data completeness4 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (no data yet)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A carcinoma that is composed of malignant large epithelial cells. This category includes large cell undifferentiated carcinomas, large cell differentiated carcinomas including large cell neuroendocrine carcinomas, and giant cell carcinomas.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

CarcinomaCancer Family

Children (11)

ncit

Breast Pleomorphic Carcinoma
Colorectal Medullary Carcinoma2 sub
Giant Cell Carcinoma5 sub
Large Cell Neuroendocrine Carcinoma2 sub
Lung Large Cell Carcinoma9 sub
Lymphoepithelial Carcinoma14 sub
Non-Keratinizing Large Cell Squamous Cell Carcinoma
Salivary Gland Large Cell Carcinoma1 sub
Small Intestinal Medullary Carcinoma

Anatomy

Anatomical sites

Data not yet available

No anatomical site linked yet.

Record

Identity

CancerIndex ID: CI-CAN-00001061
Entity type: Histology
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 4
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active): 159 / 47

3 sub

Solid Lung Adenocarcinoma

Thyroid Gland Anaplastic Carcinoma4 sub

87 descendants in total; counters on this page aggregate over all of them.

Publications (all / 5y)

2,694 / 223

Evidence items

5

Genes / variants

3 / 3

Drugs (any / approved)

6 / 2

Genomic cohorts

0

Epidemiology / survival obs.

0 / 0

Data updated 1 hour agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (3)

Carcinoma, Large Cellmesh_heading · MeSH
Carcinoma, Large Cellsynonym · NCIt
Cell Carcinoma, Largesynonym · MeSH

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

No registry-level ancestor: burden figures are published for the mutually exclusive top-level site groups only, and this entity does not descend from one. Global figures (IARC / GLOBOCAN) stay under license review and SEER awaits credentials.

Active trials47countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #299 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials21countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #318 of 1,284 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items5countaccepted CIViC items · entity + descendantscivicComputedrank #250 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months47countPubMed records · stored query · 12-month windowpubmedComputedrank #467 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts0countopen GDC projects · entity + descendantsgdcComputednot in a current ranking snapshot

Data updated 1 hour agoSource updated unknownregistry figures: none · counters aggregate over descendants