KRAS

← targets

Salirasibsmall_molecule

—

INHIBITOR

—

Curated

chembl

← targets

Adagrasibsmall_molecule

—

INHIBITOR

—

Curated

chembl

Malignant Neoplasm,Melanoma,Hepatocellular Carcinoma+2

KRAS has variant …HAS_VARIANTderived168 of 168show fewer
→ has variant	Mutationother 49 accepted CIViC evidence items	—	—	Malignant Neoplasm,Melanoma,Hepatocellular Carcinoma+2	49	Curated	civic	graph →
→ has variant	G12DSNV 23 accepted CIViC evidence items	—	—	Melanoma,Hairy Cell Leukemia,Malignant Lung Neoplasm+2	23	Curated	civic	graph →
→ has variant	G12CSNV 18 accepted CIViC evidence items	—	—	Malignant Neoplasm,Solid Neoplasm,Malignant Lung Neoplasm+2	18	Curated	civic	graph →
→ has variant	G13DSNV 15 accepted CIViC evidence items	—	—	Malignant Breast Neoplasm,Malignant Colorectal Neoplasm	15	Curated	civic	graph →
→ has variant	G12/G13 12 accepted CIViC evidence items	—	—	Lung Non-Small Cell Carcinoma,Malignant Colorectal Neoplasm,Pancreatic Adenocarcinoma	12	Curated	civic	graph →
→ has variant	G12VSNV 12 accepted CIViC evidence items	—	—	Malignant Neoplasm,Malignant Lung Neoplasm,Lung Non-Small Cell Carcinoma+1	12	Curated	civic	graph →
→ has variant	Exon 2 MutationSNV 11 accepted CIViC evidence items	—	—	Malignant Pancreatic Neoplasm,Pancreatic Carcinoma,Malignant Colorectal Neoplasm+1	11	Curated	civic	graph →
→ has variant	G12 9 accepted CIViC evidence items	—	—	Acute Leukemia,Multiple Myeloma,Lung Non-Small Cell Carcinoma+1	9	Curated	civic	graph →
→ has variant	G12ASNV 9 accepted CIViC evidence items	—	—	Malignant Lung Neoplasm,Multiple Myeloma,Lung Adenocarcinoma+1	9	Curated	civic	graph →
→ has variant	G12SSNV 8 accepted CIViC evidence items	—	—	Malignant Lung Neoplasm,Multiple Myeloma,Malignant Colorectal Neoplasm	8	Curated	civic	graph →
→ has variant	G12RSNV 5 accepted CIViC evidence items	—	—	Malignant Pancreatic Neoplasm,Malignant Colorectal Neoplasm	5	Curated	civic	graph →
→ has variant	A146TSNV 4 accepted CIViC evidence items	—	—	Malignant Neoplasm,Malignant Colorectal Neoplasm	4	Curated	civic	graph →
→ has variant	Amplificationamplification 3 accepted CIViC evidence items	—	—	Melanoma,Cutaneous Melanoma,Malignant Endometrial Neoplasm	3	Curated	civic	graph →
→ has variant	Q61HSNV 3 accepted CIViC evidence items	—	—	Malignant Neoplasm,Malignant Colorectal Neoplasm	3	Curated	civic	graph →
→ has variant	Wildtypeother 3 accepted CIViC evidence items	—	—	Malignant Colorectal Neoplasm,Pancreatic Ductal Adenocarcinoma	3	Curated	civic	graph →
→ has variant	A146VSNV 2 accepted CIViC evidence items	—	—	Lung Non-Small Cell Carcinoma,Malignant Colorectal Neoplasm	2	Curated	civic	graph →
→ has variant	G13SNV 2 accepted CIViC evidence items	—	—	Multiple Myeloma,Malignant Colorectal Neoplasm	2	Curated	civic	graph →
→ has variant	Q61 2 accepted CIViC evidence items	—	—	Multiple Myeloma,Malignant Colorectal Neoplasm	2	Curated	civic	graph →
→ has variant	RS61764370 2 accepted CIViC evidence items	—	—	Head and Neck Squamous Cell Carcinoma,Ovarian Carcinoma	2	Curated	civic	graph →
→ has variant	A11_G12insGAinsertion 1 accepted CIViC evidence items	—	—	Colon Adenocarcinoma	1	Curated	civic	graph →
→ has variant	A146 1 accepted CIViC evidence items	—	—	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ has variant	A146PSNV 1 accepted CIViC evidence items	—	—	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ has variant	G10_A11insGinsertion 1 accepted CIViC evidence items	—	—	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ has variant	G13VSNV 1 accepted CIViC evidence items	—	—	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ has variant	Q22*SNV 1 accepted CIViC evidence items	—	—	Colon Mucinous Adenocarcinoma	1	Curated	civic	graph →
→ has variant	Q61KSNV 1 accepted CIViC evidence items	—	—	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ has variant	Q61LSNV 1 accepted CIViC evidence items	—	—	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ has variant	Q61RSNV 1 accepted CIViC evidence items	—	—	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ has variant	R164Q (exon 5b)SNV 1 accepted CIViC evidence items	—	—	Malignant Neoplasm	1	Curated	civic	graph →
→ has variant	A59GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	A59TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Activating Mutation no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Alterationother no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	EXON 1 MUTATIONS no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Exon 2-3 Mutation no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	EXON 2 Mutations no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	fas no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G12FSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G12FSindel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G12NSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G12PSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G12VSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G12WSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G13CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G13ESNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G13RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G13SSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K117NSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	KRAS4A no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	KRAS4A underexpressionexpression no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	L19FSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.101C>G (p.Pro34Arg)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.107T>A (p.Ile36Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.108delinsCC (p.Glu37fs)indel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.109_110insC (p.Glu37fs)insertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.109G>T (p.Glu37Ter)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-10C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.10T>A (p.Tyr4Asn)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-10T>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+11T>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+14deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+16A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+1G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+24A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+25T>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+28C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-12T>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-12T>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+30G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+50T>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+53A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+6T>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.111+8T>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-1G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-21T>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-2A>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-2A>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-36C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-4T>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-51deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-7T>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-8_-11-7insCinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11-8A>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.11A>T (p.Tyr4Phe)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-11G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.12T>A (p.Tyr4Ter)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.13A>G (p.Lys5Glu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.13A>T (p.Lys5Ter)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.16C>T (p.Leu6Phe)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.179G>T (p.Gly60Val)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.180_181delinsAA (p.Gln61Lys)indel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.183A>T (p.Gln61His)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.187G>A (p.Glu63Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.191A>G (p.Tyr64Cys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.193_198delinsCTTGACCAGTAC (p.Ser65_Ala66delinsLeuAspGlnTyr)indel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.1del (p.Met1*)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.204G>T (p.Arg68Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.21_22insT (p.Val8fs)insertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.21G>A (p.Val7=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.22G>T (p.Val8Leu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.24dup (p.Val9fs)insertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.27_28insCTC (p.Val9_Gly10insLeu)insertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.27T>A (p.Val9=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.27T>G (p.Val9=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.290G>A (p.Arg97Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.291-10deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.291-50A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.29_30insT (p.Ala11fs)insertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.29_31del (p.Gly10del)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.30A>G (p.Gly10=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.31G>T (p.Ala11Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.32C>A (p.Ala11Asp)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.33T>A (p.Ala11=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.34_35delinsTT (p.Gly12Phe)indel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.39C>A (p.Gly13=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.39C>T (p.Gly13=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.40G>A (p.Val14Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.422T>A (p.Phe141Tyr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.42A>T (p.Val14=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.43G>T (p.Gly15Cys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.445A>T (p.Arg149Ter)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.461A>G (p.Asp154Gly)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.461A>T (p.Asp154Val)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.4del (p.Thr2fs)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.50G>T (p.Ser17Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.5C>G (p.Thr2Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.62T>A (p.Ile21Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.65A>C (p.Gln22Pro)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.-6C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.6T>G (p.Thr2=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.74A>T (p.Gln25Leu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.75G>A (p.Gln25=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.77A>C (p.Asn26Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.80A>G (p.His27Arg)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.80A>T (p.His27Leu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.84del (p.Phe28fs)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.84T>A (p.Phe28Leu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.90C>A (p.Asp30Glu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.91G>T (p.Glu31Ter)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.95A>C (p.Tyr32Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.99T>C (p.Asp33=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_004985.5(KRAS):c.9dup (p.Tyr4fs)insertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.111+239A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.112-5C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.-11delGdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.176C>T (p.Ala59Val)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.216G>A (p.Met72Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.219G>A (p.Arg73=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.27_29dup (p.Gly10dup)insertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.351A>C (p.Lys117Asn)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.355G>A (p.Asp119Asn)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.490C>T (p.Arg164Ter)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.57G>T (p.Leu19Phe)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.64C>A (p.Gln22Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.68T>G (p.Leu23Arg)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.90C>T (p.Asp30=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_033360.4(KRAS):c.93A>G (p.Glu31=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Overexpressionexpression no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	P34RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Q22KSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Q61ESNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Q61FSindel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Q61PSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	R164GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	R164Q (exon 5a)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	S65ISNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	T74PSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	V14ISNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

KRAS has variant …HAS_VARIANTderived168 of 168show fewer

→ has variant

Mutationother

49 accepted CIViC evidence items

—

Curated

Melanoma,Hairy Cell Leukemia,Malignant Lung Neoplasm+2

→ has variant

G12DSNV

23 accepted CIViC evidence items

—

Curated

Malignant Neoplasm,Solid Neoplasm,Malignant Lung Neoplasm+2

→ has variant

G12CSNV

18 accepted CIViC evidence items

—

Curated

Malignant Breast Neoplasm,Malignant Colorectal Neoplasm

→ has variant

G13DSNV

15 accepted CIViC evidence items

—

Curated

Lung Non-Small Cell Carcinoma,Malignant Colorectal Neoplasm,Pancreatic Adenocarcinoma

→ has variant

G12/G13

12 accepted CIViC evidence items

—

Curated

Malignant Neoplasm,Malignant Lung Neoplasm,Lung Non-Small Cell Carcinoma+1

→ has variant

G12VSNV

12 accepted CIViC evidence items

—

Curated

Malignant Pancreatic Neoplasm,Pancreatic Carcinoma,Malignant Colorectal Neoplasm+1

→ has variant

Exon 2 MutationSNV

11 accepted CIViC evidence items

—

Curated

Acute Leukemia,Multiple Myeloma,Lung Non-Small Cell Carcinoma+1

→ has variant

G12

9 accepted CIViC evidence items

—

Curated

Malignant Lung Neoplasm,Multiple Myeloma,Lung Adenocarcinoma+1

→ has variant

G12ASNV

9 accepted CIViC evidence items

—

Curated

Malignant Lung Neoplasm,Multiple Myeloma,Malignant Colorectal Neoplasm

→ has variant

G12SSNV

8 accepted CIViC evidence items

—

Curated

Malignant Pancreatic Neoplasm,Malignant Colorectal Neoplasm

→ has variant

G12RSNV

5 accepted CIViC evidence items

—

Curated

Malignant Neoplasm,Malignant Colorectal Neoplasm

→ has variant

A146TSNV

4 accepted CIViC evidence items

—

Curated

Melanoma,Cutaneous Melanoma,Malignant Endometrial Neoplasm

→ has variant

Amplificationamplification

3 accepted CIViC evidence items

—

Curated

Malignant Neoplasm,Malignant Colorectal Neoplasm

→ has variant

Q61HSNV

3 accepted CIViC evidence items

—

Curated

Malignant Colorectal Neoplasm,Pancreatic Ductal Adenocarcinoma

→ has variant

Wildtypeother

3 accepted CIViC evidence items

—

Curated

Lung Non-Small Cell Carcinoma,Malignant Colorectal Neoplasm

→ has variant

A146VSNV

2 accepted CIViC evidence items

—

Curated

Multiple Myeloma,Malignant Colorectal Neoplasm

→ has variant

G13SNV

2 accepted CIViC evidence items

—

Curated

Multiple Myeloma,Malignant Colorectal Neoplasm

→ has variant

Q61

2 accepted CIViC evidence items

—

Curated

Head and Neck Squamous Cell Carcinoma,Ovarian Carcinoma

→ has variant

RS61764370

2 accepted CIViC evidence items

—

Curated

→ has variant

A11_G12insGAinsertion

1 accepted CIViC evidence items

—

Curated

→ has variant

1 accepted CIViC evidence items

—

Curated

→ has variant

A146PSNV

1 accepted CIViC evidence items

—

Curated

→ has variant

G10_A11insGinsertion

1 accepted CIViC evidence items

—

Curated

→ has variant

G13VSNV

1 accepted CIViC evidence items

—

Curated

Colon Mucinous Adenocarcinoma

→ has variant

Q22*SNV

1 accepted CIViC evidence items

—

Curated

→ has variant

Q61KSNV

1 accepted CIViC evidence items

—

Curated

→ has variant

Q61LSNV

1 accepted CIViC evidence items

—

Curated

→ has variant

Q61RSNV

1 accepted CIViC evidence items

—

Curated

→ has variant

R164Q (exon 5b)SNV

1 accepted CIViC evidence items

—

Malignant Neoplasm

Curated

→ has variant

A59GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

A59TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Activating Mutation

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Alterationother

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

EXON 1 MUTATIONS

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Exon 2-3 Mutation

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

EXON 2 Mutations

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

fas

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G12FSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G12FSindel

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G12NSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G12PSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G12VSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G12WSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G13CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G13ESNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G13RSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

G13SSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

K117NSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

KRAS4A

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

KRAS4A underexpressionexpression

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

L19FSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.101C>G (p.Pro34Arg)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.107T>A (p.Ile36Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.108delinsCC (p.Glu37fs)indel

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.109_110insC (p.Glu37fs)insertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.109G>T (p.Glu37Ter)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.-10C>GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.10T>A (p.Tyr4Asn)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-10T>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+11T>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.111+14deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+16A>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+1G>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+24A>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+25T>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+28C>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-12T>ASNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-12T>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+30G>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+50T>ASNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+53A>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+6T>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.111+8T>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-1G>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-21T>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-2A>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-2A>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-36C>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-4T>ASNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.-11-51deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-7T>ASNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.-11-8_-11-7insCinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.-11-8A>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.11A>T (p.Tyr4Phe)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.-11G>ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.12T>A (p.Tyr4Ter)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.13A>G (p.Lys5Glu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.13A>T (p.Lys5Ter)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.16C>T (p.Leu6Phe)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.179G>T (p.Gly60Val)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.180_181delinsAA (p.Gln61Lys)indel

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.183A>T (p.Gln61His)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.187G>A (p.Glu63Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.191A>G (p.Tyr64Cys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.193_198delinsCTTGACCAGTAC (p.Ser65_Ala66delinsLeuAspGlnTyr)indel

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.1del (p.Met1*)deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.204G>T (p.Arg68Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.21_22insT (p.Val8fs)insertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.21G>A (p.Val7=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.22G>T (p.Val8Leu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.24dup (p.Val9fs)insertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.27_28insCTC (p.Val9_Gly10insLeu)insertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.27T>A (p.Val9=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.27T>G (p.Val9=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.290G>A (p.Arg97Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.291-10deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.291-50A>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.29_30insT (p.Ala11fs)insertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.29_31del (p.Gly10del)deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.30A>G (p.Gly10=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.31G>T (p.Ala11Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.32C>A (p.Ala11Asp)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.33T>A (p.Ala11=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.34_35delinsTT (p.Gly12Phe)indel

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.39C>A (p.Gly13=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.39C>T (p.Gly13=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.40G>A (p.Val14Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.422T>A (p.Phe141Tyr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.42A>T (p.Val14=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.43G>T (p.Gly15Cys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.445A>T (p.Arg149Ter)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.461A>G (p.Asp154Gly)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.461A>T (p.Asp154Val)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.4del (p.Thr2fs)deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.50G>T (p.Ser17Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.5C>G (p.Thr2Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.62T>A (p.Ile21Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.65A>C (p.Gln22Pro)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.-6C>TSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.6T>G (p.Thr2=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.74A>T (p.Gln25Leu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.75G>A (p.Gln25=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.77A>C (p.Asn26Thr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.80A>G (p.His27Arg)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.80A>T (p.His27Leu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.84del (p.Phe28fs)deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.84T>A (p.Phe28Leu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.90C>A (p.Asp30Glu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.91G>T (p.Glu31Ter)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.95A>C (p.Tyr32Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_004985.5(KRAS):c.99T>C (p.Asp33=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_004985.5(KRAS):c.9dup (p.Tyr4fs)insertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.111+239A>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.112-5C>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_033360.4(KRAS):c.-11delGdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.176C>T (p.Ala59Val)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.216G>A (p.Met72Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.219G>A (p.Arg73=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_033360.4(KRAS):c.27_29dup (p.Gly10dup)insertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.351A>C (p.Lys117Asn)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.355G>A (p.Asp119Asn)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.490C>T (p.Arg164Ter)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.57G>T (p.Leu19Phe)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.64C>A (p.Gln22Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.68T>G (p.Leu23Arg)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.90C>T (p.Asp30=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_033360.4(KRAS):c.93A>G (p.Glu31=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Overexpressionexpression

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

P34RSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Q22KSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Q61ESNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Q61FSindel

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Q61PSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

R164GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

R164Q (exon 5a)SNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

S65ISNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

T74PSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

V14ISNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

Testicular Germ Cell Tumor

KRAS altered in cohorts of …ALTERED_INderived15 of 23show all (up to 200)
→ altered in cohorts of	Testicular Germ Cell Tumor 255 / 263 cases (97 %) · ssm · TCGA-TGCT	—	—	Testicular Germ Cell Tumor	1	Observed	gdc	graph →
→ altered in cohorts of	Appendix Adenocarcinoma 161 / 273 cases (59 %) · ssm · appendiceal_msk_2022	—	—	Appendix Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Ampulla of Vater Carcinoma 86 / 160 cases (54 %) · ssm · ampca_bcm_2016	—	—	Ampulla of Vater Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Colorectal Adenocarcinoma 495 / 1,134 cases (44 %) · ssm · crc_msk_2017 · largest of 14 cohorts	—	—	Colorectal Adenocarcinoma	14	Observed	cbioportal	graph →
→ altered in cohorts of	Rectal Adenocarcinoma 3,096 / 7,237 cases (43 %) · ssm · crc_msk_2026 · largest of 2 cohorts	—	—	Rectal Adenocarcinoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Colon Adenocarcinoma 183 / 429 cases (43 %) · ssm · coad_tcga_gdc · largest of 4 cohorts	—	—	Colon Adenocarcinoma	4	Observed	cbioportal	graph →
→ altered in cohorts of	Pancreatic Adenocarcinoma 168 / 412 cases (41 %) · ssm · pancreas_ctdna_msk_2025 · largest of 10 cohorts	—	—	Pancreatic Adenocarcinoma	10	Observed	cbioportal	graph →
→ altered in cohorts of	Low-Grade Serous Ovarian Cancer 38 / 119 cases (32 %) · ssm · lgsoc_mapk_msk_2022	—	—	Low-Grade Serous Ovarian Cancer	1	Observed	cbioportal	graph →
→ altered in cohorts of	Lung Adenocarcinomasubtype 787 / 2,653 cases (30 %) · ssm · luad_mskcc_2023_met_organotropism · largest of 13 cohorts	—	—	Lung Adenocarcinoma	13	Observed	cbioportal	graph →
→ altered in cohorts of	Endometrial Endometrioid Adenocarcinoma 67 / 247 cases (27 %) · ssm · uec_cptac_gdc	—	—	Endometrial Endometrioid Adenocarcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Multiple Myelomahematologic_malignancy 227 / 961 cases (24 %) · ssm · MMRF-COMMPASS · largest of 2 cohorts	—	—	Multiple Myeloma	2	Observed	gdc	graph →
→ altered in cohorts of	Lung Non-Small Cell Carcinomasubtype 523 / 2,621 cases (20 %) · ssm · nsclc_ctdx_msk_2022 · largest of 6 cohorts	—	—	Lung Non-Small Cell Carcinoma	6	Observed	cbioportal	graph →
→ altered in cohorts of	Endometrial Carcinoma 357 / 1,882 cases (19 %) · ssm · ucec_ancestry_cds_msk_2023 · largest of 8 cohorts	—	—	Endometrial Carcinoma	8	Observed	cbioportal	graph →
→ altered in cohorts of	Cholangiocarcinoma 76 / 417 cases (18 %) · ssm · chol_icgc_2017 · largest of 2 cohorts	—	—	Cholangiocarcinoma	2	Observed	cbioportal	graph →
→ altered in cohorts of	Non-Seminomatous Germ Cell Tumor 20 / 155 cases (13 %) · ssm · tgct_tcga	—	—	Non-Seminomatous Germ Cell Tumor	1	Observed	cbioportal	graph →

KRAS altered in cohorts of …ALTERED_INderived15 of 23show all (up to 200)

→ altered in cohorts of

255 / 263 cases (97 %) · ssm · TCGA-TGCT

—

Testicular Germ Cell Tumor

Observed

gdc