Variant
KRAS EXON 2 Mutations
CI-VAR-00000885Explore in graph →CIViC 74
Curated evidence
Evidence by cancer (1 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 20008640
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| Malignant Colorectal Neoplasm1 | ||||||||
| KRAS EXON 2 Mutations | (prognostic) | Prognostic | B | Does Not Support N/A | 3 | submitted | EID110531,404 Formalin-fixed paraffin-embedded tissue blocks were prospectively screened from patients over 18 with stage II or III adenocarcinoma of the colon completely resected. Patient samples were scre… (full text at CIViC) PMID 20008640 · Roth et al., 2010 · Open in CIViC | civic |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available
No ClinVar interpretation attached to this variant.