Variant · Indel
KRAS NM_004985.5(KRAS):c.180_181delinsAA (p.Gln61Lys)
CI-VAR-00342080Explore in graph →p.Gln61LysNM_004985.5:c.180_181delinsAAClinVar 3116215 rs2141510126
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 3116215 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Cardiovascular phenotype; Autosomal dominant KRAS-related disorders; Pilocytic astrocytoma; Low grade glioma; Papillary thyroid carcinoma | germline/somatic | 3 | Nov 11, 2025 | clinvar |