KRAS NM_004985.5(KRAS):c.101C>G (p.Pro34Arg)

CI-VAR-00006078Explore in graph →p.Pro34ArgNM_004985.5:c.101C>GClinVar 12590 rs104894366

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
12590	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Cardiofaciocutaneous syndrome 2; Cardio-facio-cutaneous syndrome; Noonan syndrome; Noonan syndrome 3; Acute myeloid leukemia; Autoimmune lymphoproliferative syndrome type 4; RASopathy	germline	8	Nov 25, 2024	clinvar