Ipilimumab

← predicts response to

CD28 Fusionfusion

sensitivity

Sezary Syndrome

Curated

← predicts response to

IFNGR1 Lossdeletion_cna

resistance

Curated

Ipilimumab targets …TARGETS1 of 1
→ targets	CTLA4	—	INHIBITOR	—	1	Curated	chembl	graph →

Ipilimumab targets …TARGETS1 of 1

→ targets

CTLA4

—

INHIBITOR

—

Curated

Ipilimumab investigated for …INVESTIGATED_FOR70 of 70show fewer
→ investigated for	Malignant Mesotheliomacancer_family	unknown	4	Malignant Mesothelioma	1	Curated	chembl	graph →
→ investigated for	Colorectal Neoplasmsubtype	unknown	4	Colorectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Renal Cell Carcinomasubtype	unknown	4	Renal Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Neoplasmcancer_family	unknown	4	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype	unknown	4	Lung Non-Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Melanomacancer_family	unknown	4	Melanoma	1	Curated	chembl	graph →
→ investigated for	Adrenal Cortical Carcinomasubtype	supports	C	Adrenal Cortical Carcinoma	1	Curated	civic	graph →
→ investigated for	Sezary Syndromehematologic_malignancy	supports	C	Sezary Syndrome	1	Curated	civic	graph →
→ investigated for	Lung Neoplasmcancer_family	unknown	3	Lung Neoplasm	1	Curated	chembl	graph →
→ investigated for	Kidney Neoplasmsubtype	unknown	3	Kidney Neoplasm	1	Curated	chembl	graph →
→ investigated for	Head and Neck Neoplasmcancer_family	unknown	3	Head and Neck Neoplasm	1	Curated	chembl	graph →
→ investigated for	Sarcomacancer_family	unknown	3	Sarcoma	1	Curated	chembl	graph →
→ investigated for	Glioblastomasubtype	unknown	3	Glioblastoma	1	Curated	chembl	graph →
→ investigated for	Hepatocellular Carcinomasubtype	unknown	3	Hepatocellular Carcinoma	1	Curated	chembl	graph →
→ investigated for	Gastric Neoplasmcancer_family	unknown	3	Gastric Neoplasm	1	Curated	chembl	graph →
→ investigated for	Squamous Cell Carcinomahistology	unknown	3	Squamous Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Lung Small Cell Carcinomasubtype	unknown	3	Lung Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Melanomacancer_family	supports	D	Melanoma	1	Curated	civic	graph →
→ investigated for	Nasopharyngeal Carcinomasubtype	unknown	2	Nasopharyngeal Carcinoma	1	Curated	chembl	graph →
→ investigated for	Neuroendocrine Tumorsubtype	unknown	2	Neuroendocrine Tumor	1	Curated	chembl	graph →
→ investigated for	Uveal Melanomasubtype	unknown	2	Uveal Melanoma	1	Curated	chembl	graph →
→ investigated for	Leiomyosarcomasubtype	unknown	2	Leiomyosarcoma	1	Curated	chembl	graph →
→ investigated for	Gastrointestinal Stromal Tumorsubtype	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
→ investigated for	Meningiomasubtype	unknown	2	Meningioma	1	Curated	chembl	graph →
→ investigated for	Small Cell Neuroendocrine Carcinomasubtype	unknown	2	Small Cell Neuroendocrine Carcinoma	1	Curated	chembl	graph →
→ investigated for	Pituitary Gland Neoplasmcancer_family	unknown	2	Pituitary Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Salivary Gland Neoplasmcancer_family	unknown	2	Salivary Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Neuroendocrine Carcinomasubtype	unknown	2	Neuroendocrine Carcinoma	1	Curated	chembl	graph →
→ investigated for	Undifferentiated Pleomorphic Sarcomasubtype	unknown	2	Undifferentiated Pleomorphic Sarcoma	1	Curated	chembl	graph →
→ investigated for	Rectal Neoplasmsubtype	unknown	2	Rectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Bladder Neoplasmsubtype	unknown	2	Bladder Neoplasm	1	Curated	chembl	graph →
→ investigated for	Basal Cell Carcinomahistology	unknown	2	Basal Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Liposarcomasubtype	unknown	2	Liposarcoma	1	Curated	chembl	graph →
→ investigated for	Cervical Neoplasmsubtype	unknown	2	Cervical Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lung Adenocarcinomasubtype	unknown	2	Lung Adenocarcinoma	1	Curated	chembl	graph →
→ investigated for	Colon Neoplasmsubtype	unknown	2	Colon Neoplasm	1	Curated	chembl	graph →
→ investigated for	Breast Inflammatory Carcinomasubtype	unknown	2	Breast Inflammatory Carcinoma	1	Curated	chembl	graph →
→ investigated for	Gliosarcomasubtype	unknown	2	Gliosarcoma	1	Curated	chembl	graph →
→ investigated for	Esophageal Neoplasmcancer_family	unknown	2	Esophageal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Ovarian Neoplasmsubtype	unknown	2	Ovarian Neoplasm	1	Curated	chembl	graph →
→ investigated for	Synovial Sarcomasubtype	unknown	2	Synovial Sarcoma	1	Curated	chembl	graph →
→ investigated for	Kaposi Sarcomacancer	unknown	2	Kaposi Sarcoma	1	Curated	chembl	graph →
→ investigated for	Adenocarcinomahistology	unknown	2	Adenocarcinoma	1	Curated	chembl	graph →
→ investigated for	Hodgkin Lymphomahematologic_malignancy	unknown	2	Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Merkel Cell Carcinomasubtype	unknown	2	Merkel Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Breast Neoplasmcancer_family	unknown	2	Breast Neoplasm	1	Curated	chembl	graph →
→ investigated for	Pancreatic Neoplasmsubtype	unknown	2	Pancreatic Neoplasm	1	Curated	chembl	graph →
→ investigated for	Prostate Neoplasmsubtype	unknown	2	Prostate Neoplasm	1	Curated	chembl	graph →
→ investigated for	Carcinomacancer_family	unknown	2	Carcinoma	1	Curated	chembl	graph →
→ investigated for	Myeloid Leukemiahematologic_malignancy	unknown	1	Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Leukemiacancer_family	unknown	1	Leukemia	1	Curated	chembl	graph →
→ investigated for	Triple-Negative Breast Carcinomamolecular_subtype	unknown	1	Triple-Negative Breast Carcinoma	1	Curated	chembl	graph →
→ investigated for	Cholangiocarcinomasubtype	unknown	1	Cholangiocarcinoma	1	Curated	chembl	graph →
→ investigated for	Skin Neoplasmcancer_family	unknown	1	Skin Neoplasm	1	Curated	chembl	graph →
→ investigated for	Gliomasubtype	unknown	1	Glioma	1	Curated	chembl	graph →
→ investigated for	Nerve Sheath Neoplasmcancer_family	unknown	1	Nerve Sheath Neoplasm	1	Curated	chembl	graph →
→ investigated for	Peritoneal Neoplasmcancer_family	unknown	1	Peritoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Neuroblastomasubtype	unknown	1	Neuroblastoma	1	Curated	chembl	graph →
→ investigated for	Endometrial Neoplasmsubtype	unknown	1	Endometrial Neoplasm	1	Curated	chembl	graph →
→ investigated for	Fallopian Tube Neoplasmsubtype	unknown	1	Fallopian Tube Neoplasm	1	Curated	chembl	graph →
→ investigated for	Retroperitoneal Neoplasmcancer_family	unknown	1	Retroperitoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Non-Hodgkin Lymphomahematologic_malignancy	unknown	1	Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Multiple Myelomahematologic_malignancy	unknown	1	Multiple Myeloma	1	Curated	chembl	graph →
→ investigated for	Lymphomacancer_family	unknown	1	Lymphoma	1	Curated	chembl	graph →
→ investigated for	Acute Lymphoblastic Leukemiahematologic_malignancy	unknown	1	Acute Lymphoblastic Leukemia	1	Curated	chembl	graph →
→ investigated for	Acute Myeloid Leukemiahematologic_malignancy	unknown	1	Acute Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Myelodysplastic Syndromehematologic_malignancy	unknown	1	Myelodysplastic Syndrome	1	Curated	chembl	graph →
→ investigated for	Follicular Lymphomahematologic_malignancy	unknown	1	Follicular Lymphoma	1	Curated	chembl	graph →
→ investigated for	Chronic Lymphocytic Leukemiahematologic_malignancy	unknown	1	Chronic Lymphocytic Leukemia	1	Curated	chembl	graph →
→ investigated for	Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype	unknown	1	Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Curated	chembl	graph →

Ipilimumab investigated for …INVESTIGATED_FOR70 of 70show fewer

→ investigated for

Malignant Mesotheliomacancer_family

unknown

Malignant Mesothelioma

Curated

→ investigated for

Colorectal Neoplasmsubtype

unknown

Colorectal Neoplasm

Curated

→ investigated for

Renal Cell Carcinomasubtype

unknown

Renal Cell Carcinoma

Curated

→ investigated for

Neoplasmcancer_family

unknown

Neoplasm

Curated

Lung Non-Small Cell Carcinoma

→ investigated for

Lung Non-Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Melanomacancer_family

unknown

Curated

Adrenal Cortical Carcinoma

→ investigated for

Adrenal Cortical Carcinomasubtype

supports

Curated

→ investigated for

Sezary Syndromehematologic_malignancy

supports

Sezary Syndrome

Curated

→ investigated for

Lung Neoplasmcancer_family

unknown

Lung Neoplasm

Curated

→ investigated for

Kidney Neoplasmsubtype

unknown

Kidney Neoplasm

Curated

→ investigated for

Head and Neck Neoplasmcancer_family

unknown

Head and Neck Neoplasm

Curated

→ investigated for

Sarcomacancer_family

unknown

Sarcoma

Curated

→ investigated for

Glioblastomasubtype

unknown

Glioblastoma

Curated

→ investigated for

Hepatocellular Carcinomasubtype

unknown

Hepatocellular Carcinoma

Curated

→ investigated for

Gastric Neoplasmcancer_family

unknown

Gastric Neoplasm

Curated

→ investigated for

Squamous Cell Carcinomahistology

unknown

Squamous Cell Carcinoma

Curated

Lung Small Cell Carcinoma

→ investigated for

Lung Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Melanomacancer_family

supports

Curated

→ investigated for

Nasopharyngeal Carcinomasubtype

unknown

Nasopharyngeal Carcinoma

Curated

→ investigated for

Neuroendocrine Tumorsubtype

unknown

Neuroendocrine Tumor

Curated

→ investigated for

Uveal Melanomasubtype

unknown

Uveal Melanoma

Curated

→ investigated for

Leiomyosarcomasubtype

unknown

Leiomyosarcoma

Curated

Gastrointestinal Stromal Tumor

→ investigated for

Gastrointestinal Stromal Tumorsubtype

unknown

Curated

→ investigated for

Meningiomasubtype

unknown

Meningioma

Curated

Small Cell Neuroendocrine Carcinoma

→ investigated for

Small Cell Neuroendocrine Carcinomasubtype

unknown

Curated

→ investigated for

Pituitary Gland Neoplasmcancer_family

unknown

Pituitary Gland Neoplasm

Curated

→ investigated for

Salivary Gland Neoplasmcancer_family

unknown

Salivary Gland Neoplasm

Curated

→ investigated for

Neuroendocrine Carcinomasubtype

unknown

Neuroendocrine Carcinoma

Curated

Undifferentiated Pleomorphic Sarcoma

→ investigated for

Undifferentiated Pleomorphic Sarcomasubtype

unknown

Curated

→ investigated for

Rectal Neoplasmsubtype

unknown

Rectal Neoplasm

Curated

→ investigated for

Bladder Neoplasmsubtype

unknown

Bladder Neoplasm

Curated

→ investigated for

Basal Cell Carcinomahistology

unknown

Basal Cell Carcinoma

Curated

→ investigated for

Liposarcomasubtype

unknown

Liposarcoma

Curated

→ investigated for

Cervical Neoplasmsubtype

unknown

Cervical Neoplasm

Curated

→ investigated for

Lung Adenocarcinomasubtype

unknown

Lung Adenocarcinoma

Curated

→ investigated for

Colon Neoplasmsubtype

unknown

Colon Neoplasm

Curated

Breast Inflammatory Carcinoma

→ investigated for

Breast Inflammatory Carcinomasubtype

unknown

Curated

→ investigated for

Gliosarcomasubtype

unknown

Gliosarcoma

Curated

→ investigated for

Esophageal Neoplasmcancer_family

unknown

Esophageal Neoplasm

Curated

→ investigated for

Ovarian Neoplasmsubtype

unknown

Ovarian Neoplasm

Curated

→ investigated for

Synovial Sarcomasubtype

unknown

Synovial Sarcoma

Curated

→ investigated for

Kaposi Sarcomacancer

unknown

Kaposi Sarcoma

Curated

→ investigated for

Adenocarcinomahistology

unknown

Adenocarcinoma

Curated

→ investigated for

Hodgkin Lymphomahematologic_malignancy

unknown

Hodgkin Lymphoma

Curated

→ investigated for

Merkel Cell Carcinomasubtype

unknown

Merkel Cell Carcinoma

Curated

→ investigated for

Breast Neoplasmcancer_family

unknown

Breast Neoplasm

Curated

→ investigated for

Pancreatic Neoplasmsubtype

unknown

Pancreatic Neoplasm

Curated

→ investigated for

Prostate Neoplasmsubtype

unknown

Prostate Neoplasm

Curated

→ investigated for

Carcinomacancer_family

unknown

Carcinoma

Curated

→ investigated for

Myeloid Leukemiahematologic_malignancy

unknown

Myeloid Leukemia

Curated

→ investigated for

Leukemiacancer_family

unknown

Leukemia

Curated

Triple-Negative Breast Carcinoma

→ investigated for

Triple-Negative Breast Carcinomamolecular_subtype

unknown

Curated

→ investigated for

Cholangiocarcinomasubtype

unknown

Cholangiocarcinoma

Curated

→ investigated for

Skin Neoplasmcancer_family

unknown

Skin Neoplasm

Curated

→ investigated for

Gliomasubtype

unknown

Glioma

Curated

→ investigated for

Nerve Sheath Neoplasmcancer_family

unknown

Nerve Sheath Neoplasm

Curated

→ investigated for

Peritoneal Neoplasmcancer_family

unknown

Peritoneal Neoplasm

Curated

→ investigated for

Neuroblastomasubtype

unknown

Neuroblastoma

Curated

→ investigated for

Endometrial Neoplasmsubtype

unknown

Endometrial Neoplasm

Curated

→ investigated for

Fallopian Tube Neoplasmsubtype

unknown

Fallopian Tube Neoplasm

Curated

→ investigated for

Retroperitoneal Neoplasmcancer_family

unknown

Retroperitoneal Neoplasm

Curated

→ investigated for

Non-Hodgkin Lymphomahematologic_malignancy

unknown

Non-Hodgkin Lymphoma

Curated

→ investigated for

Multiple Myelomahematologic_malignancy

unknown

Multiple Myeloma

Curated

→ investigated for

Lymphomacancer_family

unknown

Lymphoma

Curated

Acute Lymphoblastic Leukemia

→ investigated for

Acute Lymphoblastic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Acute Myeloid Leukemiahematologic_malignancy

unknown

Acute Myeloid Leukemia

Curated

→ investigated for

Myelodysplastic Syndromehematologic_malignancy

unknown

Myelodysplastic Syndrome

Curated

→ investigated for

Follicular Lymphomahematologic_malignancy

unknown

Follicular Lymphoma

Curated

Chronic Lymphocytic Leukemia

→ investigated for

Chronic Lymphocytic Leukemiahematologic_malignancy

unknown

Curated

Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ investigated for

Chronic Myeloid Leukemia, BCR-ABL1 Positivemolecular_subtype

unknown

Curated

Ipilimumab investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 436show all (up to 200)
→ investigated in trials for	Melanomacancer_family 202 trials (45 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Melanoma	202	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Non-Small Cell Carcinomasubtype 59 trials (21 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Small Cell Carcinoma	59	Observed	clinicaltrials	graph →
→ investigated in trials for	Renal Cell Carcinomasubtype 50 trials (27 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Renal Cell Carcinoma	50	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Neoplasm 31 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Neoplasm	31	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Prostate Neoplasm 25 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Prostate Neoplasm	25	Observed	clinicaltrials	graph →
→ investigated in trials for	Solid Neoplasm 25 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Solid Neoplasm	25	Observed	clinicaltrials	graph →
→ investigated in trials for	Cutaneous Melanomacancer 23 trials (10 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Cutaneous Melanoma	23	Observed	clinicaltrials	graph →
→ investigated in trials for	Uveal Melanomasubtype 23 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Uveal Melanoma	23	Observed	clinicaltrials	graph →
→ investigated in trials for	Hepatocellular Carcinomasubtype 21 trials (9 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Hepatocellular Carcinoma	21	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Pancreatic Neoplasm 20 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Pancreatic Neoplasm	20	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Solid Neoplasm 20 trials (9 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Solid Neoplasm	20	Observed	clinicaltrials	graph →
→ investigated in trials for	Clear Cell Renal Cell Carcinoma 19 trials (16 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Clear Cell Renal Cell Carcinoma	19	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Lung Neoplasm 19 trials (8 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Lung Neoplasm	19	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Breast Neoplasm 15 trials (5 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Breast Neoplasm	15	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Colorectal Neoplasmsubtype 14 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Colorectal Neoplasm	14	Observed	clinicaltrials	graph →

Ipilimumab investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 436show all (up to 200)

→ investigated in trials for

Melanomacancer_family

202 trials (45 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

202

Observed

Lung Non-Small Cell Carcinoma

→ investigated in trials for

Lung Non-Small Cell Carcinomasubtype

59 trials (21 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Renal Cell Carcinomasubtype

50 trials (27 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Renal Cell Carcinoma

Observed

→ investigated in trials for

Malignant Neoplasm

31 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Neoplasm

Observed

Malignant Prostate Neoplasm

→ investigated in trials for

25 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Prostate Neoplasm

Observed

→ investigated in trials for

Solid Neoplasm

25 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Solid Neoplasm

Observed

→ investigated in trials for

Cutaneous Melanomacancer

23 trials (10 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Cutaneous Melanoma

Observed

→ investigated in trials for

Uveal Melanomasubtype

23 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Uveal Melanoma

Observed

→ investigated in trials for

Hepatocellular Carcinomasubtype

21 trials (9 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Hepatocellular Carcinoma

Observed

Malignant Pancreatic Neoplasm

→ investigated in trials for

20 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Pancreatic Neoplasm

Observed

→ investigated in trials for

Malignant Solid Neoplasm

20 trials (9 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Solid Neoplasm

Observed

Clear Cell Renal Cell Carcinoma

→ investigated in trials for

19 trials (16 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Clear Cell Renal Cell Carcinoma

Observed

→ investigated in trials for

Malignant Lung Neoplasm

19 trials (8 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Lung Neoplasm

Observed

Malignant Breast Neoplasm

→ investigated in trials for

15 trials (5 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Breast Neoplasm

Observed

Malignant Colorectal Neoplasm

→ investigated in trials for

Malignant Colorectal Neoplasmsubtype

14 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Ipilimumab studied in …STUDIED_INderived10 of 681show all (up to 200)
→ studied in	NCT01896999Phase 1/Phase 2 · active not recruiting Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma · 681 trials list this drug (203 active)	—	—	Classic Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03866382Phase 2 · recruiting Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · 681 trials list this drug (203 active)	—	—	Malignant Genitourinary System Neoplasm,Large Cell Neuroendocrine Carcinoma,Sarcomatoid Renal Cell Carcinoma+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT04751370Phase 2 · active not recruiting Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer · 681 trials list this drug (203 active)	—	—	Malignant Rectal Neoplasm,Rectal Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05112601Phase 2 · recruiting Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma · 681 trials list this drug (203 active)	—	—	Endometrioid Adenocarcinoma,Endometrial Adenocarcinoma,Endometrial Carcinoma+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT07227012Phase 1/Phase 2 · recruiting Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body. · 681 trials list this drug (203 active)	—	—	Liver Neoplasm,Hepatocellular Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07401875Phase 1 · recruiting A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK) · 681 trials list this drug (203 active)	—	—	Malignant Kidney Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05188118early Phase 1 · completed Rapid Sequencing of Approved Therapies in Patients With Metastatic or Unresectable Clear Cell Renal Cell Carcinoma · 681 trials list this drug (203 active)	—	—	Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06047379Phase 1/Phase 2 · recruiting Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis · 681 trials list this drug (203 active)	—	—	Melanoma,Malignant Esophageal Neoplasm,Malignant Gastric Neoplasm+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT07838974Phase 1 · not yet recruiting Adding Anakinra and Tocilizumab to Nivolumab and Ipilimumab for the Treatment of Melanoma Patients 50 Years of Age or Older · 681 trials list this drug (203 active)	—	—	Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03816345Phase 1 · recruiting Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO · 681 trials list this drug (203 active)	—	—	Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm	1	Observed	clinicaltrials	graph →

Ipilimumab studied in …STUDIED_INderived10 of 681show all (up to 200)

→ studied in

NCT01896999Phase 1/Phase 2 · active not recruiting

Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma · 681 trials list this drug (203 active)

—

Classic Hodgkin Lymphoma

Observed

Malignant Genitourinary System Neoplasm,Large Cell Neuroendocrine Carcinoma,Sarcomatoid Renal Cell Carcinoma+2

→ studied in

NCT03866382Phase 2 · recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · 681 trials list this drug (203 active)

—

Observed

Malignant Rectal Neoplasm,Rectal Adenocarcinoma

→ studied in

NCT04751370Phase 2 · active not recruiting

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer · 681 trials list this drug (203 active)

—

Observed

Endometrioid Adenocarcinoma,Endometrial Adenocarcinoma,Endometrial Carcinoma+2

→ studied in

NCT05112601Phase 2 · recruiting

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma · 681 trials list this drug (203 active)

—

Observed

Liver Neoplasm,Hepatocellular Carcinoma

→ studied in

NCT07227012Phase 1/Phase 2 · recruiting

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body. · 681 trials list this drug (203 active)

—

Observed

Malignant Kidney Neoplasm

→ studied in

NCT07401875Phase 1 · recruiting

A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK) · 681 trials list this drug (203 active)

—

Observed

→ studied in

NCT05188118early Phase 1 · completed

Rapid Sequencing of Approved Therapies in Patients With Metastatic or Unresectable Clear Cell Renal Cell Carcinoma · 681 trials list this drug (203 active)

—

Renal Cell Carcinoma

Observed

Melanoma,Malignant Esophageal Neoplasm,Malignant Gastric Neoplasm+2

→ studied in

NCT06047379Phase 1/Phase 2 · recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis · 681 trials list this drug (203 active)

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Observed

→ studied in

NCT07838974Phase 1 · not yet recruiting

Adding Anakinra and Tocilizumab to Nivolumab and Ipilimumab for the Treatment of Melanoma Patients 50 Years of Age or Older · 681 trials list this drug (203 active)

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Observed

Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm

→ studied in

NCT03816345Phase 1 · recruiting

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO · 681 trials list this drug (203 active)

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Observed