KIT

← targets

Tivozanibsmall_molecule

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INHIBITOR

—

Curated

← targets

Tandutinibsmall_molecule

—

INHIBITOR

—

Curated

← targets

Sunitinibsmall_molecule

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INHIBITOR

—

Curated

← targets

Sorafenib Tosylatesmall_molecule

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INHIBITOR

—

Curated

← targets

Sorafenibsmall_molecule

—

INHIBITOR

—

Curated

← targets

Ripretinibsmall_molecule

—

INHIBITOR

—

Curated

← targets

Regorafenib Anhydroussmall_molecule

—

INHIBITOR

—

Curated

← targets

Regorafenibsmall_molecule

—

INHIBITOR

—

Curated

← targets

Quizartinibsmall_molecule

—

INHIBITOR

—

Curated

← targets

Pexidartinibsmall_molecule

—

INHIBITOR

—

Curated

← targets

Pazopanibsmall_molecule

—

INHIBITOR

—

Curated

← targets

Motesanibsmall_molecule

—

INHIBITOR

—

Curated

← targets

Midostaurinsmall_molecule

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INHIBITOR

—

Curated

← targets

Masitinibsmall_molecule

—

INHIBITOR

—

Curated

Melanoma,Gastrointestinal Stromal Tumor,Malignant Lung Neoplasm

KIT has variant …HAS_VARIANTderived200 of 3,442show all (up to 200)
→ has variant	Exon 11 Mutation 13 accepted CIViC evidence items	—	—	Melanoma,Gastrointestinal Stromal Tumor,Malignant Lung Neoplasm	13	Curated	civic	graph →
→ has variant	D816VSNV 8 accepted CIViC evidence items	—	—	Malignant Neoplasm,Acute Myeloid Leukemia,Chronic Myeloid Leukemia, BCR-ABL1 Positive+1	8	Curated	civic	graph →
→ has variant	Exon 9 Mutation 8 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	8	Curated	civic	graph →
→ has variant	N822KSNV 8 accepted CIViC evidence items	—	—	Malignant Neoplasm,Gastrointestinal Stromal Tumor,Acute Myeloid Leukemia	8	Curated	civic	graph →
→ has variant	W557_K558deldeletion 6 accepted CIViC evidence items	—	—	Malignant Neoplasm,Gastrointestinal Stromal Tumor	6	Curated	civic	graph →
→ has variant	L576PSNV 5 accepted CIViC evidence items	—	—	Malignant Neoplasm,Melanoma,Gastrointestinal Stromal Tumor+1	5	Curated	civic	graph →
→ has variant	EXPRESSIONexpression 4 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor,Glioblastoma,Malignant Endometrial Neoplasm	4	Curated	civic	graph →
→ has variant	K642ESNV 4 accepted CIViC evidence items	—	—	Malignant Neoplasm,Melanoma,Gastrointestinal Stromal Tumor+1	4	Curated	civic	graph →
→ has variant	T670ISNV 4 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	4	Curated	civic	graph →
→ has variant	V560DSNV 4 accepted CIViC evidence items	—	—	Malignant Neoplasm,Gastrointestinal Stromal Tumor	4	Curated	civic	graph →
→ has variant	D820YSNV 3 accepted CIViC evidence items	—	—	Melanoma,Gastrointestinal Stromal Tumor	3	Curated	civic	graph →
→ has variant	M541LSNV 3 accepted CIViC evidence items	—	—	Chronic Leukemia,Chronic Myeloid Leukemia, BCR-ABL1 Positive	3	Curated	civic	graph →
→ has variant	V559DSNV 3 accepted CIViC evidence items	—	—	Malignant Neoplasm,Gastrointestinal Stromal Tumor	3	Curated	civic	graph →
→ has variant	A502_Y503insAYinsertion 2 accepted CIViC evidence items	—	—	Malignant Neoplasm	2	Curated	civic	graph →
→ has variant	A829PSNV 2 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	2	Curated	civic	graph →
→ has variant	D816ESNV 2 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	2	Curated	civic	graph →
→ has variant	Mutationother 2 accepted CIViC evidence items	—	—	Melanoma,Gastrointestinal Stromal Tumor	2	Curated	civic	graph →
→ has variant	P551_E554delPMYEdeletion 2 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	2	Curated	civic	graph →
→ has variant	S628NSNV 2 accepted CIViC evidence items	—	—	Malignant Neoplasm,Melanoma	2	Curated	civic	graph →
→ has variant	V560GSNV 2 accepted CIViC evidence items	—	—	Malignant Neoplasm,Gastrointestinal Stromal Tumor	2	Curated	civic	graph →
→ has variant	V560_L576deldeletion 2 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	2	Curated	civic	graph →
→ has variant	V654ASNV 2 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	2	Curated	civic	graph →
→ has variant	A502_Y503dup 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	Amplificationamplification 1 accepted CIViC evidence items	—	—	Mucosal Melanoma	1	Curated	civic	graph →
→ has variant	C809GSNV 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	D579deldeletion 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	D816HSNV 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	D820ASNV 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	D820GSNV 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	Exon 13 Mutation 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	Exon 14 Mutation 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	F506_F508DUP 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	Internal Duplicationinsertion 1 accepted CIViC evidence items	—	—	Anal Melanoma	1	Curated	civic	graph →
→ has variant	K484_G487DELdeletion 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	K550_K558deldeletion 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	K550_K559DELdeletion 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	K550_W557deldeletion 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	K558delinsNPindel 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	K558_V559deldeletion 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	N822HSNV 1 accepted CIViC evidence items	—	—	Malignant Neoplasm	1	Curated	civic	graph →
→ has variant	rs17084733 1 accepted CIViC evidence items	—	—	Acral Lentiginous Melanoma	1	Curated	civic	graph →
→ has variant	RS3733542SNV 1 accepted CIViC evidence items	—	—	Acute Myeloid Leukemia	1	Curated	civic	graph →
→ has variant	T417_D419delinsYindel 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	V555_V559DELdeletion 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	V560DELdeletion 1 accepted CIViC evidence items	—	—	Thymus Carcinoma	1	Curated	civic	graph →
→ has variant	V560_Y578deldeletion 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	Wildtypeother 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	Y503_F504insAYinsertion 1 accepted CIViC evidence items	—	—	Malignant Neoplasm	1	Curated	civic	graph →
→ has variant	Y823DSNV 1 accepted CIViC evidence items	—	—	Gastrointestinal Stromal Tumor	1	Curated	civic	graph →
→ has variant	557/558 in-frame deletion/delinsinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D419deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D496VSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D579_H580insIDPTQLPYDinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D816FSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D816FSindel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D816GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D816YSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	D820ESNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	DEL 554-558deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	E554DSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Exon 11 557_560delWKVVE no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Exon 11 577-582insPYDinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Exon 11 W557deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	EXON 17 MUTATIONS no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Exon 9 and Exon 11 Mutations no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	F504ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	F522CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Fusionfusion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	H697YSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K550_W557delKPMYEVQWdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K558QSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K558RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K642RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	M552_W557DELdeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	N505ISNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	N505RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	N512DSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	N822KSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	N822KSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000004.11:g.(?_55524172)_(55524258_?)dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000004.11:g.(?_55561668)_(55604733_?)dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000004.11:g.(?_55569884)_(55604729_?)dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000004.11:g.(?_55589740)_(55604733_?)dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NC_000004.12:g.54657928_54658032dupinsertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1000_1003dup (p.Val335fs)insertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1002T>C (p.Ile334=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1002T>G (p.Ile334Met)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1003G>A (p.Val335Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1005T>G (p.Val335=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1006G>A (p.Glu336Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1008A>G (p.Glu336=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1010A>G (p.Tyr337Cys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.10_11delinsTT (p.Ala4Phe)indel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1011T>C (p.Tyr337=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1016C>T (p.Ala339Val)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1017A>G (p.Ala339=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1017A>T (p.Ala339=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1018T>A (p.Phe340Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1018T>G (p.Phe340Val)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.101C>A (p.Pro34Gln)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.101C>T (p.Pro34Leu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1020C>T (p.Phe340=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1021C>T (p.Pro341Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1023C>G (p.Pro341=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1023C>T (p.Pro341=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1025A>C (p.Lys342Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1025A>G (p.Lys342Arg)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1025A>T (p.Lys342Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1027C>T (p.Pro343Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1029T>C (p.Pro343=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.102G>A (p.Pro34=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1030G>A (p.Glu344Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1032A>G (p.Glu344=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1033C>T (p.His345Tyr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1035C>G (p.His345Gln)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1036C>G (p.Gln346Glu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1036C>T (p.Gln346Ter)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1038G>A (p.Gln346=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1038G>T (p.Gln346His)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1040A>G (p.Gln347Arg)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1041G>A (p.Gln347=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1045A>G (p.Ile349Val)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1045A>T (p.Ile349Phe)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1046T>C (p.Ile349Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1047C>T (p.Ile349=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1049A>G (p.Tyr350Cys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1050T>C (p.Tyr350=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1051A>G (p.Met351Val)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1053G>A (p.Met351Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1054A>G (p.Asn352Asp)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1055A>G (p.Asn352Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1056C>G (p.Asn352Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1056C>T (p.Asn352=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1057A>C (p.Arg353=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1057A>G (p.Arg353Gly)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1058G>A (p.Arg353Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1059A>G (p.Arg353=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.*1059C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.105T>A (p.Ser35=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1061C>T (p.Thr354Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1062C>G (p.Thr354=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1063T>A (p.Phe355Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1066A>C (p.Thr356Pro)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1066A>G (p.Thr356Ala)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1067C>G (p.Thr356Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1069G>C (p.Asp357His)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.106C>A (p.Pro36Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.106C>G (p.Pro36Ala)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.106C>T (p.Pro36Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1070A>G (p.Asp357Gly)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1071T>A (p.Asp357Glu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1072A>G (p.Lys358Glu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1073A>C (p.Lys358Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1074A>G (p.Lys358=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1079A>G (p.Glu360Gly)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.107C>T (p.Pro36Leu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1080A>C (p.Glu360Asp)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.108_109insT (p.Pro37fs)insertion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1081G>A (p.Asp361Asn)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1081G>T (p.Asp361Tyr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1083T>C (p.Asp361=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1085A>T (p.Tyr362Phe)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.*1086C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1086T>C (p.Tyr362=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.*1087G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1089C>A (p.Pro363=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1089C>G (p.Pro363=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1089C>T (p.Pro363=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.108A>G (p.Pro36=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1091A>G (p.Lys364Arg)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1095T>A (p.Ser365=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1098G>A (p.Glu366=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1098G>C (p.Glu366Asp)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.10G>A (p.Ala4Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.10G>C (p.Ala4Pro)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.10G>T (p.Ala4Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1100A>C (p.Asn367Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1100A>G (p.Asn367Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.*1101A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1101T>C (p.Asn367=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1102G>A (p.Glu368Lys)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1105A>C (p.Ser369Arg)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1106G>A (p.Ser369Asn)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1106G>C (p.Ser369Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1106G>T (p.Ser369Ile)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1108A>C (p.Asn370His)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1109A>G (p.Asn370Ser)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1112T>C (p.Ile371Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1114A>G (p.Arg372Gly)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+10G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+10G>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+11G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+12A>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+13C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+13C>GSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+13C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+14C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+16deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+17G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_000222.3(KIT):c.1115+17G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

KIT has variant …HAS_VARIANTderived200 of 3,442show all (up to 200)

→ has variant

Exon 11 Mutation

13 accepted CIViC evidence items

—

Curated

Malignant Neoplasm,Acute Myeloid Leukemia,Chronic Myeloid Leukemia, BCR-ABL1 Positive+1

→ has variant

D816VSNV

8 accepted CIViC evidence items

—

Curated

→ has variant

Exon 9 Mutation

8 accepted CIViC evidence items

—

Curated

Malignant Neoplasm,Gastrointestinal Stromal Tumor,Acute Myeloid Leukemia

→ has variant

N822KSNV

8 accepted CIViC evidence items

—

Curated

→ has variant

W557_K558deldeletion

6 accepted CIViC evidence items

—

Curated

Malignant Neoplasm,Melanoma,Gastrointestinal Stromal Tumor+1

→ has variant

L576PSNV

5 accepted CIViC evidence items

—

Curated

Gastrointestinal Stromal Tumor,Glioblastoma,Malignant Endometrial Neoplasm

→ has variant

EXPRESSIONexpression

4 accepted CIViC evidence items

—

Curated

Malignant Neoplasm,Melanoma,Gastrointestinal Stromal Tumor+1

→ has variant

K642ESNV

4 accepted CIViC evidence items

—

Curated

→ has variant

T670ISNV

4 accepted CIViC evidence items

—

Curated

→ has variant

V560DSNV

4 accepted CIViC evidence items

—

Curated

Melanoma,Gastrointestinal Stromal Tumor

→ has variant

D820YSNV

3 accepted CIViC evidence items

—

Curated

Chronic Leukemia,Chronic Myeloid Leukemia, BCR-ABL1 Positive

→ has variant

M541LSNV

3 accepted CIViC evidence items

—

Curated

→ has variant

V559DSNV

3 accepted CIViC evidence items

—

Curated

→ has variant

A502_Y503insAYinsertion

2 accepted CIViC evidence items

—

Malignant Neoplasm

Curated

→ has variant

A829PSNV

2 accepted CIViC evidence items

—

Curated

→ has variant

D816ESNV

2 accepted CIViC evidence items

—

Curated

Melanoma,Gastrointestinal Stromal Tumor

→ has variant

Mutationother

2 accepted CIViC evidence items

—

Curated

→ has variant

P551_E554delPMYEdeletion

2 accepted CIViC evidence items

—

Curated

Malignant Neoplasm,Melanoma

→ has variant

S628NSNV

2 accepted CIViC evidence items

—

Curated

→ has variant

V560GSNV

2 accepted CIViC evidence items

—

Curated

→ has variant

V560_L576deldeletion

2 accepted CIViC evidence items

—

Curated

→ has variant

V654ASNV

2 accepted CIViC evidence items

—

Curated

→ has variant

A502_Y503dup

1 accepted CIViC evidence items

—

Curated

→ has variant

Amplificationamplification

1 accepted CIViC evidence items

—

Mucosal Melanoma

Curated

→ has variant

C809GSNV

1 accepted CIViC evidence items

—

Curated

→ has variant

D579deldeletion

1 accepted CIViC evidence items

—

Curated

→ has variant

D816HSNV

1 accepted CIViC evidence items

—

Curated

→ has variant

D820ASNV

1 accepted CIViC evidence items

—

Curated

→ has variant

D820GSNV

1 accepted CIViC evidence items

—

Curated

→ has variant

Exon 13 Mutation

1 accepted CIViC evidence items

—

Curated

→ has variant

Exon 14 Mutation

1 accepted CIViC evidence items

—

Curated

→ has variant

F506_F508DUP

1 accepted CIViC evidence items

—

Curated

→ has variant

Internal Duplicationinsertion

1 accepted CIViC evidence items

—

Anal Melanoma

Curated

→ has variant

K484_G487DELdeletion

1 accepted CIViC evidence items

—

Curated

→ has variant

K550_K558deldeletion

1 accepted CIViC evidence items

—

Curated

→ has variant

K550_K559DELdeletion

1 accepted CIViC evidence items

—

Curated

→ has variant

K550_W557deldeletion

1 accepted CIViC evidence items

—

Curated

→ has variant

K558delinsNPindel

1 accepted CIViC evidence items

—

Curated

→ has variant

K558_V559deldeletion

1 accepted CIViC evidence items

—

Curated

Acral Lentiginous Melanoma

→ has variant

N822HSNV

1 accepted CIViC evidence items

—

Curated

→ has variant

1 accepted CIViC evidence items

—

Curated

→ has variant

RS3733542SNV

1 accepted CIViC evidence items

—

Acute Myeloid Leukemia

Curated

→ has variant

T417_D419delinsYindel

1 accepted CIViC evidence items

—

Curated

→ has variant

V555_V559DELdeletion

1 accepted CIViC evidence items

—

Curated

→ has variant

V560DELdeletion

1 accepted CIViC evidence items

—

Thymus Carcinoma

Curated

→ has variant

V560_Y578deldeletion

1 accepted CIViC evidence items

—

Curated

→ has variant

Wildtypeother

1 accepted CIViC evidence items

—

Curated

→ has variant

Y503_F504insAYinsertion

1 accepted CIViC evidence items

—

Malignant Neoplasm

Curated

→ has variant

Y823DSNV

1 accepted CIViC evidence items

—

Curated

→ has variant

557/558 in-frame deletion/delinsinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

D419deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

D496VSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

D579_H580insIDPTQLPYDinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

D816FSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

D816FSindel

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

D816GSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

D816YSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

D820ESNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

DEL 554-558deletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

E554DSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Exon 11 557_560delWKVVE

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Exon 11 577-582insPYDinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Exon 11 W557deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

EXON 17 MUTATIONS

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

Exon 9 and Exon 11 Mutations

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

F504ASNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

F522CSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

Fusionfusion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

H697YSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

K550_W557delKPMYEVQWdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

K558QSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

K558RSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

K642RSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

M552_W557DELdeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

N505ISNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

N505RSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

N512DSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

N822KSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

N822KSNV

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NC_000004.11:g.(?_55524172)_(55524258_?)dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NC_000004.11:g.(?_55561668)_(55604733_?)dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NC_000004.11:g.(?_55569884)_(55604729_?)dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NC_000004.11:g.(?_55589740)_(55604733_?)dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NC_000004.12:g.54657928_54658032dupinsertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_000222.3(KIT):c.1000_1003dup (p.Val335fs)insertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1002T>C (p.Ile334=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1002T>G (p.Ile334Met)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1003G>A (p.Val335Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1005T>G (p.Val335=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1006G>A (p.Glu336Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1008A>G (p.Glu336=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1010A>G (p.Tyr337Cys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_000222.3(KIT):c.10_11delinsTT (p.Ala4Phe)indel

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1011T>C (p.Tyr337=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1016C>T (p.Ala339Val)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1017A>G (p.Ala339=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1017A>T (p.Ala339=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1018T>A (p.Phe340Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1018T>G (p.Phe340Val)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.101C>A (p.Pro34Gln)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.101C>T (p.Pro34Leu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1020C>T (p.Phe340=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1021C>T (p.Pro341Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1023C>G (p.Pro341=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1023C>T (p.Pro341=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1025A>C (p.Lys342Thr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1025A>G (p.Lys342Arg)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1025A>T (p.Lys342Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1027C>T (p.Pro343Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1029T>C (p.Pro343=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.102G>A (p.Pro34=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1030G>A (p.Glu344Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1032A>G (p.Glu344=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1033C>T (p.His345Tyr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1035C>G (p.His345Gln)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1036C>G (p.Gln346Glu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1036C>T (p.Gln346Ter)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1038G>A (p.Gln346=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1038G>T (p.Gln346His)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1040A>G (p.Gln347Arg)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1041G>A (p.Gln347=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1045A>G (p.Ile349Val)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1045A>T (p.Ile349Phe)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1046T>C (p.Ile349Thr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1047C>T (p.Ile349=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1049A>G (p.Tyr350Cys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1050T>C (p.Tyr350=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1051A>G (p.Met351Val)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1053G>A (p.Met351Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1054A>G (p.Asn352Asp)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1055A>G (p.Asn352Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1056C>G (p.Asn352Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1056C>T (p.Asn352=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1057A>C (p.Arg353=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1057A>G (p.Arg353Gly)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1058G>A (p.Arg353Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1059A>G (p.Arg353=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.*1059C>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.105T>A (p.Ser35=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1061C>T (p.Thr354Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1062C>G (p.Thr354=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1063T>A (p.Phe355Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1066A>C (p.Thr356Pro)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1066A>G (p.Thr356Ala)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1067C>G (p.Thr356Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1069G>C (p.Asp357His)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.106C>A (p.Pro36Thr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.106C>G (p.Pro36Ala)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.106C>T (p.Pro36Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1070A>G (p.Asp357Gly)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1071T>A (p.Asp357Glu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1072A>G (p.Lys358Glu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1073A>C (p.Lys358Thr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1074A>G (p.Lys358=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1079A>G (p.Glu360Gly)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.107C>T (p.Pro36Leu)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1080A>C (p.Glu360Asp)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_000222.3(KIT):c.108_109insT (p.Pro37fs)insertion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1081G>A (p.Asp361Asn)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1081G>T (p.Asp361Tyr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1083T>C (p.Asp361=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1085A>T (p.Tyr362Phe)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.*1086C>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1086T>C (p.Tyr362=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.*1087G>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1089C>A (p.Pro363=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1089C>G (p.Pro363=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1089C>T (p.Pro363=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.108A>G (p.Pro36=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1091A>G (p.Lys364Arg)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1095T>A (p.Ser365=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1098G>A (p.Glu366=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1098G>C (p.Glu366Asp)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.10G>A (p.Ala4Thr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.10G>C (p.Ala4Pro)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.10G>T (p.Ala4Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1100A>C (p.Asn367Thr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1100A>G (p.Asn367Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.*1101A>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1101T>C (p.Asn367=)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1102G>A (p.Glu368Lys)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1105A>C (p.Ser369Arg)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1106G>A (p.Ser369Asn)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1106G>C (p.Ser369Thr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1106G>T (p.Ser369Ile)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1108A>C (p.Asn370His)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1109A>G (p.Asn370Ser)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1112T>C (p.Ile371Thr)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1114A>G (p.Arg372Gly)SNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+10G>ASNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+10G>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+11G>ASNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+12A>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+13C>ASNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+13C>GSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+13C>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+14C>TSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

→ has variant

NM_000222.3(KIT):c.1115+16deldeletion

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+17G>ASNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

NM_000222.3(KIT):c.1115+17G>CSNV

→ has variant

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

KIT altered in cohorts of …ALTERED_INderived5 of 5
→ altered in cohorts of	Gastrointestinal Stromal Tumorsubtype 384 / 499 cases (77 %) · ssm · gist_msk_2022 · largest of 3 cohorts	—	—	Gastrointestinal Stromal Tumor	3	Observed	cbioportal	graph →
→ altered in cohorts of	Skin Basal Cell Carcinoma 59 / 293 cases (20 %) · ssm · bcc_unige_2016	—	—	Skin Basal Cell Carcinoma	1	Observed	cbioportal	graph →
→ altered in cohorts of	Non-Seminomatous Germ Cell Tumor 28 / 155 cases (18 %) · ssm · tgct_tcga · largest of 2 cohorts	—	—	Non-Seminomatous Germ Cell Tumor	2	Observed	cbioportal	graph →
→ altered in cohorts of	Acute Myeloid Leukemiahematologic_malignancy 88 / 887 cases (9.9 %) · ssm · aml_stjude_2024 · largest of 2 cohorts	—	—	Acute Myeloid Leukemia	2	Observed	cbioportal	graph →
→ altered in cohorts of	Cutaneous Melanoma 39 / 696 cases (5.6 %) · ssm · mel_mskimpact_2020	—	—	Cutaneous Melanoma	1	Observed	cbioportal	graph →

KIT altered in cohorts of …ALTERED_INderived5 of 5

→ altered in cohorts of

Gastrointestinal Stromal Tumorsubtype

384 / 499 cases (77 %) · ssm · gist_msk_2022 · largest of 3 cohorts

—

Observed

cbioportal