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Chronic Leukemia · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Malignant Neoplasm
Leukemia
Chronic Leukemia

Hematologic Malignancy

Chronic Leukemia

CI-CAN-00000764Explore in graph →

Hematologic410 active trials10 approved drugs59 evidence items

NCIt: C3483
DOID: 1036

Overview
Statistics
Survival
Genomics1
Variants & evidence59
Drugs7
Trials1704
Research
Rankings
Sources & provenance

Data completeness5 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A slowly progressing leukemia characterized by a clonal (malignant) proliferation of maturing and mature myeloid cells or mature lymphocytes. When the clonal cellular population is composed of myeloid cells, the process is called chronic myelogenous leukemia. When the clonal cellular population is composed of lymphocytes, it is classified as chronic lymphocytic leukemia, hairy cell leukemia, or T-cell large granular lymphocyte leukemia.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

LeukemiaCancer Family

Children (12)

ncit

Aggressive NK-Cell Leukemia
Atypical Chronic Myeloid Leukemia
Chronic Eosinophilic Leukemia, Not Otherwise Specified
Chronic Eosinophilic Leukemia with FIP1L1-PDGFRA
Chronic Lymphocytic Leukemia10 sub
Chronic Myelomonocytic Leukemia9 sub
Chronic Neutrophilic Leukemia
Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive1 sub
Hairy Cell Leukemia1 sub

Anatomy

Anatomical sites

Hematopoietic and Lymphatic SystemC35813

Record

Identity

CancerIndex ID: CI-CAN-00000764
Entity type: Hematologic Malignancy
Malignant: Yes
Solid / hematologic: Hematologic
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 4
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

Hairy Cell Leukemia Variant

Prolymphocytic Leukemia3 sub

T-Cell Large Granular Lymphocyte Leukemia3 sub

41 descendants in total; counters on this page aggregate over all of them.

1,704 / 410

Publications (all / 5y)

907 / 91

Evidence items

59

Genes / variants

20 / 41

Drugs (any / approved)

7 / 10

Genomic cohorts

1

Epidemiology / survival obs.

0 / 0

Data updated 18 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (1)

Chronic Leukemiasynonym · CIViC

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths23,740countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #7 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Leukemia (registry level) — open Leukemia
US new cases58,254countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #11 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Leukemia (registry level) — open Leukemia
US age-standardized mortality5.5per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #6 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Leukemia (registry level) — open Leukemia
Active trials410countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #93 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials207countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #99 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items59countaccepted CIViC items · entity + descendantscivicComputedrank #72 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months18countPubMed records · stored query · 12-month windowpubmedComputedrank #762 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts1countopen GDC projects · entity + descendantsgdcComputedrank #228 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 18 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants