Gemcitabine

← predicts response to

ERCC1 Underexpressionexpression

sensitivity

Curated

Malignant Bladder Neoplasm

← predicts response to

FGFR3 Mutationother

sensitivity

Curated

← predicts response to

BRCA2 Mutationother

sensitivity

Curated

← predicts response to

BRCA1 Mutationother

sensitivity

Curated

← predicts response to

WEE1 RS3910384

sensitivity

Curated

← predicts response to

SLC29A1 Overexpressionexpression

sensitivity

Curated

← predicts response to

KRAS Exon 2 MutationSNV

resistance

Curated

← predicts response to

XRCC1 R194WSNV

sensitivity

Curated

← predicts response to

KRAS G12/G13

resistance

Curated

← predicts response to

BARD1 G320*SNV

sensitivity

Lung Adenocarcinoma

Curated

← predicts response to

RRM2 OVEREXPRESSIONexpression

resistance

Curated

← predicts response to

RRM1 Overexpressionexpression

resistance

Curated

← predicts response to

RB1 Overexpressionexpression

resistance

Curated

← predicts response to

MAGEH1 EXPRESSIONexpression

resistance

Bile Duct Adenocarcinoma

Curated

Gemcitabine targets …TARGETS14 of 14
→ targets	POLE2	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	POLE3	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	PRIM2	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	POLA2	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	POLE	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	PRIM1	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	POLD1	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	POLD2	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	POLD3	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	POLA1	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	POLD4	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	RRM2	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	RRM2B	—	INHIBITOR	—	1	Curated	chembl	graph →
→ targets	RRM1	—	INHIBITOR	—	1	Curated	chembl	graph →

Gemcitabine targets …TARGETS14 of 14

→ targets

POLE2

—

INHIBITOR

—

Curated

→ targets

POLE3

—

INHIBITOR

—

Curated

→ targets

PRIM2

—

INHIBITOR

—

Curated

→ targets

POLA2

—

INHIBITOR

—

Curated

→ targets

POLE

—

INHIBITOR

—

Curated

→ targets

PRIM1

—

INHIBITOR

—

Curated

→ targets

POLD1

—

INHIBITOR

—

Curated

→ targets

POLD2

—

INHIBITOR

—

Curated

→ targets

POLD3

—

INHIBITOR

—

Curated

→ targets

POLA1

—

INHIBITOR

—

Curated

→ targets

POLD4

—

INHIBITOR

—

Curated

→ targets

RRM2

—

INHIBITOR

—

Curated

→ targets

RRM2B

—

INHIBITOR

—

Curated

→ targets

RRM1

—

INHIBITOR

—

Curated

Gemcitabine investigated for …INVESTIGATED_FOR87 of 87show fewer
→ investigated for	Lung Non-Small Cell Carcinomasubtype 7 source records aggregated	supports	B	Lung Non-Small Cell Carcinoma	7	Curated	civic	graph →
→ investigated for	Malignant Pancreatic Neoplasmcancer 5 source records aggregated	supports	B	Malignant Pancreatic Neoplasm	5	Curated	civic	graph →
→ investigated for	Pancreatic Adenocarcinomasubtype 2 source records aggregated	supports	B	Pancreatic Adenocarcinoma	2	Curated	civic	graph →
→ investigated for	Malignant Bladder Neoplasmcancer	supports	B	Malignant Bladder Neoplasm	1	Curated	civic	graph →
→ investigated for	Ovarian Neoplasmsubtype	unknown	4	Ovarian Neoplasm	1	Curated	chembl	graph →
→ investigated for	Breast Neoplasmcancer_family	unknown	4	Breast Neoplasm	1	Curated	chembl	graph →
→ investigated for	Pancreatic Neoplasmsubtype	unknown	4	Pancreatic Neoplasm	1	Curated	chembl	graph →
→ investigated for	Neoplasmcancer_family	unknown	4	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype	unknown	4	Lung Non-Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Lung Adenocarcinomasubtype	supports	C	Lung Adenocarcinoma	1	Curated	civic	graph →
→ investigated for	Female Reproductive System Neoplasmsubtype	unknown	3	Female Reproductive System Neoplasm	1	Curated	chembl	graph →
→ investigated for	Nasopharyngeal Carcinomasubtype	unknown	3	Nasopharyngeal Carcinoma	1	Curated	chembl	graph →
→ investigated for	Hepatoblastomacancer_family	unknown	3	Hepatoblastoma	1	Curated	chembl	graph →
→ investigated for	Lung Neoplasmcancer_family	unknown	3	Lung Neoplasm	1	Curated	chembl	graph →
→ investigated for	Liver Neoplasmsubtype	unknown	3	Liver Neoplasm	1	Curated	chembl	graph →
→ investigated for	Urethra Neoplasmsubtype	unknown	3	Urethra Neoplasm	1	Curated	chembl	graph →
→ investigated for	Peritoneal Neoplasmcancer_family	unknown	3	Peritoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Gallbladder Neoplasmsubtype	unknown	3	Gallbladder Neoplasm	1	Curated	chembl	graph →
→ investigated for	Non-Hodgkin Lymphomahematologic_malignancy	unknown	3	Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Squamous Cell Carcinomahistology	unknown	3	Squamous Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Typehematologic_malignancy	unknown	3	Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type	1	Curated	chembl	graph →
→ investigated for	Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy	unknown	3	Peripheral T-Cell Lymphoma, Not Otherwise Specified	1	Curated	chembl	graph →
→ investigated for	Hepatocellular Carcinomasubtype	unknown	3	Hepatocellular Carcinoma	1	Curated	chembl	graph →
→ investigated for	Follicular Lymphomahematologic_malignancy	unknown	3	Follicular Lymphoma	1	Curated	chembl	graph →
→ investigated for	Fallopian Tube Neoplasmsubtype	unknown	3	Fallopian Tube Neoplasm	1	Curated	chembl	graph →
→ investigated for	Triple-Negative Breast Carcinomamolecular_subtype	unknown	3	Triple-Negative Breast Carcinoma	1	Curated	chembl	graph →
→ investigated for	Hodgkin Lymphomahematologic_malignancy	unknown	3	Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Nasopharyngeal Neoplasmsubtype	unknown	3	Nasopharyngeal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Carcinomacancer_family	unknown	3	Carcinoma	1	Curated	chembl	graph →
→ investigated for	Cervical Neoplasmsubtype	unknown	3	Cervical Neoplasm	1	Curated	chembl	graph →
→ investigated for	Sarcomacancer_family	unknown	3	Sarcoma	1	Curated	chembl	graph →
→ investigated for	Bladder Neoplasmsubtype	unknown	3	Bladder Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lymphomacancer_family	unknown	3	Lymphoma	1	Curated	chembl	graph →
→ investigated for	Cholangiocarcinomasubtype	unknown	3	Cholangiocarcinoma	1	Curated	chembl	graph →
→ investigated for	Malignant Mesotheliomacancer_family	unknown	3	Malignant Mesothelioma	1	Curated	chembl	graph →
→ investigated for	Malignant Pancreatic Neoplasmcancer 3 source records aggregated	supports	D	Malignant Pancreatic Neoplasm	3	Curated	civic	graph →
→ investigated for	Pancreatic Ductal Adenocarcinomasubtype 2 source records aggregated	supports	D	Pancreatic Ductal Adenocarcinoma	2	Curated	civic	graph →
→ investigated for	Pancreatic Adenocarcinomasubtype	supports	D	Pancreatic Adenocarcinoma	1	Curated	civic	graph →
→ investigated for	Bile Duct Adenocarcinomasubtype	supports	D	Bile Duct Adenocarcinoma	1	Curated	civic	graph →
→ investigated for	Mantle Cell Lymphomahematologic_malignancy	supports	D	Mantle Cell Lymphoma	1	Curated	civic	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype	supports	D	Lung Non-Small Cell Carcinoma	1	Curated	civic	graph →
→ investigated for	Bone Neoplasmsubtype	unknown	2	Bone Neoplasm	1	Curated	chembl	graph →
→ investigated for	Olfactory Neuroblastomasubtype	unknown	2	Olfactory Neuroblastoma	1	Curated	chembl	graph →
→ investigated for	Gliomasubtype	unknown	2	Glioma	1	Curated	chembl	graph →
→ investigated for	Uterine Neoplasmsubtype	unknown	2	Uterine Neoplasm	1	Curated	chembl	graph →
→ investigated for	Vulvar Neoplasmsubtype	unknown	2	Vulvar Neoplasm	1	Curated	chembl	graph →
→ investigated for	Gastrointestinal Stromal Tumorsubtype	unknown	2	Gastrointestinal Stromal Tumor	1	Curated	chembl	graph →
→ investigated for	Ovarian Carcinomasubtype	unknown	2	Ovarian Carcinoma	1	Curated	chembl	graph →
→ investigated for	Ewing Sarcomasubtype	unknown	2	Ewing Sarcoma	1	Curated	chembl	graph →
→ investigated for	Colon Neoplasmsubtype	unknown	2	Colon Neoplasm	1	Curated	chembl	graph →
→ investigated for	Esophageal Neoplasmcancer_family	unknown	2	Esophageal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Adult T-Cell Leukemia/Lymphomahematologic_malignancy	unknown	2	Adult T-Cell Leukemia/Lymphoma	1	Curated	chembl	graph →
→ investigated for	T-Cell Non-Hodgkin Lymphomahematologic_malignancy	unknown	2	T-Cell Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Bile Duct Neoplasmsubtype	unknown	2	Bile Duct Neoplasm	1	Curated	chembl	graph →
→ investigated for	Thyroid Gland Neoplasmsubtype	unknown	2	Thyroid Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Ureter Neoplasmsubtype	unknown	2	Ureter Neoplasm	1	Curated	chembl	graph →
→ investigated for	Endometrial Neoplasmsubtype	unknown	2	Endometrial Neoplasm	1	Curated	chembl	graph →
→ investigated for	Kidney Neoplasmsubtype	unknown	2	Kidney Neoplasm	1	Curated	chembl	graph →
→ investigated for	Serous Cystadenomahistology	unknown	2	Serous Cystadenoma	1	Curated	chembl	graph →
→ investigated for	Lung Adenocarcinomasubtype	unknown	2	Lung Adenocarcinoma	1	Curated	chembl	graph →
→ investigated for	Plasma Cell Leukemiahematologic_malignancy	unknown	2	Plasma Cell Leukemia	1	Curated	chembl	graph →
→ investigated for	Plasmacytomahematologic_malignancy	unknown	2	Plasmacytoma	1	Curated	chembl	graph →
→ investigated for	Rectal Neoplasmsubtype	unknown	2	Rectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Testicular Neoplasmsubtype	unknown	2	Testicular Neoplasm	1	Curated	chembl	graph →
→ investigated for	Large Cell Carcinomahistology	unknown	2	Large Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Anaplastic Large Cell Lymphomahematologic_malignancy	unknown	2	Anaplastic Large Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Medulloblastomasubtype	unknown	2	Medulloblastoma	1	Curated	chembl	graph →
→ investigated for	Melanomacancer_family	unknown	2	Melanoma	1	Curated	chembl	graph →
→ investigated for	Osteosarcomasubtype	unknown	2	Osteosarcoma	1	Curated	chembl	graph →
→ investigated for	Leiomyosarcomasubtype	unknown	2	Leiomyosarcoma	1	Curated	chembl	graph →
→ investigated for	Colorectal Neoplasmsubtype	unknown	2	Colorectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Acute Lymphoblastic Leukemiahematologic_malignancy	unknown	2	Acute Lymphoblastic Leukemia	1	Curated	chembl	graph →
→ investigated for	Mantle Cell Lymphomahematologic_malignancy	unknown	2	Mantle Cell Lymphoma	1	Curated	chembl	graph →
→ investigated for	Head and Neck Neoplasmcancer_family	unknown	2	Head and Neck Neoplasm	1	Curated	chembl	graph →
→ investigated for	Multiple Myelomahematologic_malignancy	unknown	2	Multiple Myeloma	1	Curated	chembl	graph →
→ investigated for	Renal Cell Carcinomasubtype	unknown	2	Renal Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Adenocarcinomahistology	unknown	2	Adenocarcinoma	1	Curated	chembl	graph →
→ investigated for	Lung Small Cell Carcinomasubtype	unknown	2	Lung Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Leukemiacancer_family	unknown	2	Leukemia	1	Curated	chembl	graph →
→ investigated for	Acute Myeloid Leukemiahematologic_malignancy	unknown	1	Acute Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Brain Neoplasmsubtype	unknown	1	Brain Neoplasm	1	Curated	chembl	graph →
→ investigated for	Synovial Sarcomasubtype	unknown	1	Synovial Sarcoma	1	Curated	chembl	graph →
→ investigated for	Gastric Neoplasmcancer_family	unknown	1	Gastric Neoplasm	1	Curated	chembl	graph →
→ investigated for	Hilar Cholangiocarcinomasubtype	unknown	1	Hilar Cholangiocarcinoma	1	Curated	chembl	graph →
→ investigated for	Mycosis Fungoideshematologic_malignancy	unknown	1	Mycosis Fungoides	1	Curated	chembl	graph →
→ investigated for	Primary Cutaneous T-Cell Non-Hodgkin Lymphomahematologic_malignancy	unknown	1	Primary Cutaneous T-Cell Non-Hodgkin Lymphoma	1	Curated	chembl	graph →
→ investigated for	Diffuse Intrinsic Pontine Gliomasubtype	unknown	0.5	Diffuse Intrinsic Pontine Glioma	1	Curated	chembl	graph →

Gemcitabine investigated for …INVESTIGATED_FOR87 of 87show fewer

→ investigated for

7 source records aggregated

supports

Curated

→ investigated for

Malignant Pancreatic Neoplasmcancer

5 source records aggregated

supports

Curated

→ investigated for

Pancreatic Adenocarcinomasubtype

2 source records aggregated

supports

Curated

Malignant Bladder Neoplasm

→ investigated for

Malignant Bladder Neoplasmcancer

supports

Curated

→ investigated for

Ovarian Neoplasmsubtype

unknown

Ovarian Neoplasm

Curated

→ investigated for

Breast Neoplasmcancer_family

unknown

Breast Neoplasm

Curated

→ investigated for

Pancreatic Neoplasmsubtype

unknown

Pancreatic Neoplasm

Curated

→ investigated for

Neoplasmcancer_family

unknown

Neoplasm

Curated

→ investigated for

unknown

Curated

→ investigated for

Lung Adenocarcinomasubtype

supports

Lung Adenocarcinoma

Curated

Female Reproductive System Neoplasm

→ investigated for

Female Reproductive System Neoplasmsubtype

unknown

Curated

→ investigated for

Nasopharyngeal Carcinomasubtype

unknown

Nasopharyngeal Carcinoma

Curated

→ investigated for

Hepatoblastomacancer_family

unknown

Hepatoblastoma

Curated

→ investigated for

Lung Neoplasmcancer_family

unknown

Lung Neoplasm

Curated

→ investigated for

Liver Neoplasmsubtype

unknown

Liver Neoplasm

Curated

→ investigated for

Urethra Neoplasmsubtype

unknown

Urethra Neoplasm

Curated

→ investigated for

Peritoneal Neoplasmcancer_family

unknown

Peritoneal Neoplasm

Curated

→ investigated for

Gallbladder Neoplasmsubtype

unknown

Gallbladder Neoplasm

Curated

→ investigated for

Non-Hodgkin Lymphomahematologic_malignancy

unknown

Non-Hodgkin Lymphoma

Curated

→ investigated for

Squamous Cell Carcinomahistology

unknown

Squamous Cell Carcinoma

Curated

Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type

→ investigated for

Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Typehematologic_malignancy

unknown

Curated

Peripheral T-Cell Lymphoma, Not Otherwise Specified

→ investigated for

Peripheral T-Cell Lymphoma, Not Otherwise Specifiedhematologic_malignancy

unknown

Curated

→ investigated for

Hepatocellular Carcinomasubtype

unknown

Hepatocellular Carcinoma

Curated

→ investigated for

Follicular Lymphomahematologic_malignancy

unknown

Follicular Lymphoma

Curated

→ investigated for

Fallopian Tube Neoplasmsubtype

unknown

Fallopian Tube Neoplasm

Curated

Triple-Negative Breast Carcinoma

→ investigated for

Triple-Negative Breast Carcinomamolecular_subtype

unknown

Curated

→ investigated for

Hodgkin Lymphomahematologic_malignancy

unknown

Hodgkin Lymphoma

Curated

→ investigated for

Nasopharyngeal Neoplasmsubtype

unknown

Nasopharyngeal Neoplasm

Curated

→ investigated for

Carcinomacancer_family

unknown

Carcinoma

Curated

→ investigated for

Cervical Neoplasmsubtype

unknown

Cervical Neoplasm

Curated

→ investigated for

Sarcomacancer_family

unknown

Sarcoma

Curated

→ investigated for

Bladder Neoplasmsubtype

unknown

Bladder Neoplasm

Curated

→ investigated for

Lymphomacancer_family

unknown

Lymphoma

Curated

→ investigated for

Cholangiocarcinomasubtype

unknown

Cholangiocarcinoma

Curated

→ investigated for

Malignant Mesotheliomacancer_family

unknown

Malignant Mesothelioma

Curated

→ investigated for

Malignant Pancreatic Neoplasmcancer

3 source records aggregated

supports

Curated

Pancreatic Ductal Adenocarcinoma

→ investigated for

Pancreatic Ductal Adenocarcinomasubtype

2 source records aggregated

supports

Curated

→ investigated for

Pancreatic Adenocarcinomasubtype

supports

Curated

→ investigated for

Bile Duct Adenocarcinomasubtype

supports

Bile Duct Adenocarcinoma

Curated

→ investigated for

Mantle Cell Lymphomahematologic_malignancy

supports

Mantle Cell Lymphoma

Curated

→ investigated for

supports

Curated

→ investigated for

Bone Neoplasmsubtype

unknown

Bone Neoplasm

Curated

→ investigated for

Olfactory Neuroblastomasubtype

unknown

Olfactory Neuroblastoma

Curated

→ investigated for

Gliomasubtype

unknown

Glioma

Curated

→ investigated for

Uterine Neoplasmsubtype

unknown

Uterine Neoplasm

Curated

→ investigated for

Vulvar Neoplasmsubtype

unknown

Vulvar Neoplasm

Curated

Gastrointestinal Stromal Tumor

→ investigated for

Gastrointestinal Stromal Tumorsubtype

unknown

Curated

→ investigated for

Ovarian Carcinomasubtype

unknown

Ovarian Carcinoma

Curated

→ investigated for

Ewing Sarcomasubtype

unknown

Ewing Sarcoma

Curated

→ investigated for

Colon Neoplasmsubtype

unknown

Colon Neoplasm

Curated

→ investigated for

Esophageal Neoplasmcancer_family

unknown

Esophageal Neoplasm

Curated

Adult T-Cell Leukemia/Lymphoma

→ investigated for

Adult T-Cell Leukemia/Lymphomahematologic_malignancy

unknown

Curated

T-Cell Non-Hodgkin Lymphoma

→ investigated for

T-Cell Non-Hodgkin Lymphomahematologic_malignancy

unknown

Curated

→ investigated for

Bile Duct Neoplasmsubtype

unknown

Bile Duct Neoplasm

Curated

→ investigated for

Thyroid Gland Neoplasmsubtype

unknown

Thyroid Gland Neoplasm

Curated

→ investigated for

Ureter Neoplasmsubtype

unknown

Ureter Neoplasm

Curated

→ investigated for

Endometrial Neoplasmsubtype

unknown

Endometrial Neoplasm

Curated

→ investigated for

Kidney Neoplasmsubtype

unknown

Kidney Neoplasm

Curated

→ investigated for

Serous Cystadenomahistology

unknown

Serous Cystadenoma

Curated

→ investigated for

Lung Adenocarcinomasubtype

unknown

Lung Adenocarcinoma

Curated

→ investigated for

Plasma Cell Leukemiahematologic_malignancy

unknown

Plasma Cell Leukemia

Curated

→ investigated for

Plasmacytomahematologic_malignancy

unknown

Plasmacytoma

Curated

→ investigated for

Rectal Neoplasmsubtype

unknown

Rectal Neoplasm

Curated

→ investigated for

Testicular Neoplasmsubtype

unknown

Testicular Neoplasm

Curated

→ investigated for

Large Cell Carcinomahistology

unknown

Large Cell Carcinoma

Curated

Anaplastic Large Cell Lymphoma

→ investigated for

Anaplastic Large Cell Lymphomahematologic_malignancy

unknown

Curated

→ investigated for

Medulloblastomasubtype

unknown

Medulloblastoma

Curated

→ investigated for

Melanomacancer_family

unknown

Melanoma

Curated

→ investigated for

Osteosarcomasubtype

unknown

Osteosarcoma

Curated

→ investigated for

Leiomyosarcomasubtype

unknown

Leiomyosarcoma

Curated

→ investigated for

Colorectal Neoplasmsubtype

unknown

Colorectal Neoplasm

Curated

Acute Lymphoblastic Leukemia

→ investigated for

Acute Lymphoblastic Leukemiahematologic_malignancy

unknown

Curated

→ investigated for

Mantle Cell Lymphomahematologic_malignancy

unknown

Mantle Cell Lymphoma

Curated

→ investigated for

Head and Neck Neoplasmcancer_family

unknown

Head and Neck Neoplasm

Curated

→ investigated for

Multiple Myelomahematologic_malignancy

unknown

Multiple Myeloma

Curated

→ investigated for

Renal Cell Carcinomasubtype

unknown

Renal Cell Carcinoma

Curated

→ investigated for

Adenocarcinomahistology

unknown

Adenocarcinoma

Curated

Lung Small Cell Carcinoma

→ investigated for

Lung Small Cell Carcinomasubtype

unknown

Curated

→ investigated for

Leukemiacancer_family

unknown

Leukemia

Curated

→ investigated for

Acute Myeloid Leukemiahematologic_malignancy

unknown

Acute Myeloid Leukemia

Curated

→ investigated for

Brain Neoplasmsubtype

unknown

Brain Neoplasm

Curated

→ investigated for

Synovial Sarcomasubtype

unknown

Synovial Sarcoma

Curated

→ investigated for

Gastric Neoplasmcancer_family

unknown

Gastric Neoplasm

Curated

→ investigated for

Hilar Cholangiocarcinomasubtype

unknown

Hilar Cholangiocarcinoma

Curated

→ investigated for

Mycosis Fungoideshematologic_malignancy

unknown

Mycosis Fungoides

Curated

Primary Cutaneous T-Cell Non-Hodgkin Lymphoma

→ investigated for

Primary Cutaneous T-Cell Non-Hodgkin Lymphomahematologic_malignancy

unknown

Curated

Diffuse Intrinsic Pontine Glioma

→ investigated for

Diffuse Intrinsic Pontine Gliomasubtype

unknown

0.5

Curated

Gemcitabine investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 416show all (up to 200)
→ investigated in trials for	Malignant Pancreatic Neoplasmcancer 455 trials (74 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Pancreatic Neoplasm	455	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Non-Small Cell Carcinomasubtype 169 trials (32 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Small Cell Carcinoma	169	Observed	clinicaltrials	graph →
→ investigated in trials for	Pancreatic Adenocarcinomasubtype 118 trials (27 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Pancreatic Adenocarcinoma	118	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Breast Neoplasmcancer_family 112 trials (14 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Breast Neoplasm	112	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Lung Neoplasm 108 trials (13 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Lung Neoplasm	108	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Bladder Neoplasmcancer 102 trials (25 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Bladder Neoplasm	102	Observed	clinicaltrials	graph →
→ investigated in trials for	Solid Neoplasm 76 trials (15 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Solid Neoplasm	76	Observed	clinicaltrials	graph →
→ investigated in trials for	Pancreatic Neoplasmsubtype 75 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Pancreatic Neoplasm	75	Observed	clinicaltrials	graph →
→ investigated in trials for	Pancreatic Ductal Adenocarcinomasubtype 66 trials (39 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Pancreatic Ductal Adenocarcinoma	66	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Ovarian Neoplasmcancer 60 trials (8 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Ovarian Neoplasm	60	Observed	clinicaltrials	graph →
→ investigated in trials for	Lymphomacancer_family 49 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lymphoma	49	Observed	clinicaltrials	graph →
→ investigated in trials for	Adult Solid Neoplasm 46 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Adult Solid Neoplasm	46	Observed	clinicaltrials	graph →
→ investigated in trials for	Pancreatic Carcinoma 46 trials (10 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Pancreatic Carcinoma	46	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Neoplasm 45 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Neoplasm	45	Observed	clinicaltrials	graph →
→ investigated in trials for	Cholangiocarcinomasubtype 44 trials (13 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Cholangiocarcinoma	44	Observed	clinicaltrials	graph →

Gemcitabine investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 416show all (up to 200)

→ investigated in trials for

Malignant Pancreatic Neoplasmcancer

455 trials (74 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

455

Observed

→ investigated in trials for

169 trials (32 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

169

Observed

→ investigated in trials for

Pancreatic Adenocarcinomasubtype

118 trials (27 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

118

Observed

Malignant Breast Neoplasm

→ investigated in trials for

Malignant Breast Neoplasmcancer_family

112 trials (14 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

112

Observed

→ investigated in trials for

Malignant Lung Neoplasm

108 trials (13 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Lung Neoplasm

108

Observed

Malignant Bladder Neoplasm

→ investigated in trials for

Malignant Bladder Neoplasmcancer

102 trials (25 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

102

Observed

→ investigated in trials for

Solid Neoplasm

76 trials (15 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Solid Neoplasm

Observed

→ investigated in trials for

Pancreatic Neoplasmsubtype

75 trials (7 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Pancreatic Neoplasm

Observed

Pancreatic Ductal Adenocarcinoma

→ investigated in trials for

Pancreatic Ductal Adenocarcinomasubtype

66 trials (39 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Malignant Ovarian Neoplasm

→ investigated in trials for

Malignant Ovarian Neoplasmcancer

60 trials (8 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Lymphomacancer_family

49 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Lymphoma

Observed

→ investigated in trials for

Adult Solid Neoplasm

46 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Adult Solid Neoplasm

Observed

→ investigated in trials for

Pancreatic Carcinoma

46 trials (10 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Pancreatic Carcinoma

Observed

→ investigated in trials for

Malignant Neoplasm

45 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Neoplasm

Observed

→ investigated in trials for

Cholangiocarcinomasubtype

44 trials (13 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Cholangiocarcinoma

Observed

Lymphoma,Hodgkin Lymphoma,Chronic Myelomonocytic Leukemia+2

Gemcitabine studied in …STUDIED_INderived10 of 2,012show all (up to 200)
→ studied in	NCT03418038Phase 2 · recruiting Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia · 2,012 trials list this drug (440 active)	—	—	Lymphoma,Hodgkin Lymphoma,Chronic Myelomonocytic Leukemia+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT03734029Phase 3 · completed Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04] · 2,012 trials list this drug (440 active)	—	—	Malignant Breast Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05007106Phase 2 · completed MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) · 2,012 trials list this drug (440 active)	—	—	Esophageal Neoplasm,Gastric Neoplasm,Gallbladder Neoplasm+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT05482893Phase 1/Phase 2 · recruiting Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study) · 2,012 trials list this drug (440 active)	—	—	Malignant Biliary Tract Neoplasm,Malignant Colorectal Neoplasm,Pancreatic Ductal Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05712356Phase 2 · completed A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors · 2,012 trials list this drug (440 active)	—	—	Intrahepatic Cholangiocarcinoma,Malignant Bile Duct Neoplasm,Malignant Gallbladder Neoplasm+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT06619236Phase 3 · active not recruiting Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer · 2,012 trials list this drug (440 active)	—	—	Platinum-Resistant Ovarian Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06623422Phase 3 · recruiting A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009) · 2,012 trials list this drug (440 active)	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06694454Phase 1/Phase 2 · suspended Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC) · 2,012 trials list this drug (440 active)	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06770582Phase 2 · recruiting Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial · 2,012 trials list this drug (440 active)	—	—	Malignant Bladder Neoplasm,Non-Muscle Invasive Bladder Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06788912Phase 2 · active not recruiting Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01) · 2,012 trials list this drug (440 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →

Gemcitabine studied in …STUDIED_INderived10 of 2,012show all (up to 200)

→ studied in

NCT03418038Phase 2 · recruiting

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia · 2,012 trials list this drug (440 active)

—

Observed

Malignant Breast Neoplasm

→ studied in

NCT03734029Phase 3 · completed

Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04] · 2,012 trials list this drug (440 active)

—

Observed

Esophageal Neoplasm,Gastric Neoplasm,Gallbladder Neoplasm+2

→ studied in

NCT05007106Phase 2 · completed

MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) · 2,012 trials list this drug (440 active)

—

Observed

Malignant Biliary Tract Neoplasm,Malignant Colorectal Neoplasm,Pancreatic Ductal Adenocarcinoma

→ studied in

NCT05482893Phase 1/Phase 2 · recruiting

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study) · 2,012 trials list this drug (440 active)

—

Observed

Intrahepatic Cholangiocarcinoma,Malignant Bile Duct Neoplasm,Malignant Gallbladder Neoplasm+2

→ studied in

NCT05712356Phase 2 · completed

A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors · 2,012 trials list this drug (440 active)

—

Observed

Platinum-Resistant Ovarian Carcinoma

→ studied in

NCT06619236Phase 3 · active not recruiting

Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer · 2,012 trials list this drug (440 active)

—

Observed

→ studied in

NCT06623422Phase 3 · recruiting

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009) · 2,012 trials list this drug (440 active)

—

Observed

→ studied in

NCT06694454Phase 1/Phase 2 · suspended

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC) · 2,012 trials list this drug (440 active)

—

Observed

Malignant Bladder Neoplasm,Non-Muscle Invasive Bladder Urothelial Carcinoma

→ studied in

NCT06770582Phase 2 · recruiting

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial · 2,012 trials list this drug (440 active)

—

Observed

→ studied in

NCT06788912Phase 2 · active not recruiting

Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01) · 2,012 trials list this drug (440 active)

—

not mapped

Observed