Erlotinib

Curated

← predicts response to

EGFR L858RSNV

2 source records aggregated

sensitivity

Curated

← predicts response to

EGFR T790MSNV

resistance

Curated

← predicts response to

EGFR L858RSNV

6 source records aggregated

sensitivity

Curated

← predicts response to

EGFR Exon 19 Deletiondeletion

5 source records aggregated

sensitivity

Curated

Lung Non-Small Cell Carcinoma,Malignant Lung Neoplasm

← predicts response to

EGFR Mutationother

4 source records aggregated

sensitivity

Curated

← predicts response to

KRAS Mutationother

3 source records aggregated

resistance

Curated

← predicts response to

EGFR G719

2 source records aggregated

sensitivity

Curated

← predicts response to

EGFR T790MSNV

2 source records aggregated

resistance

Curated

← predicts response to

EGFR Amplificationamplification

2 source records aggregated

sensitivity

Curated

← predicts response to

KRAS Mutationother

sensitivity

Curated

← predicts response to

GNAS c.393T>CSNV

resistance

Curated

← predicts response to

EGFR Exon 18 Overexpressionexpression

sensitivity

Curated

← predicts response to

EGFR L861

sensitivity

Curated

← predicts response to

PIK3CA Mutationother

resistance

Curated

Erlotinib targets …TARGETS1 of 1
→ targets	EGFR	—	INHIBITOR	—	1	Curated	chembl	graph →

Erlotinib targets …TARGETS1 of 1

→ targets

EGFR

—

INHIBITOR

—

Curated

Erlotinib investigated for …INVESTIGATED_FOR78 of 78show fewer
→ investigated for	Lung Non-Small Cell Carcinomasubtype 4 source records aggregated	supports	A	Lung Non-Small Cell Carcinoma	4	Curated	civic	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype 26 source records aggregated	supports	B	Lung Non-Small Cell Carcinoma	26	Curated	civic	graph →
→ investigated for	Lung Adenocarcinomasubtype 5 source records aggregated	supports	B	Lung Adenocarcinoma	5	Curated	civic	graph →
→ investigated for	Glioblastomasubtype 2 source records aggregated	supports	B	Glioblastoma	2	Curated	civic	graph →
→ investigated for	Malignant Lung Neoplasmcancer	supports	B	Malignant Lung Neoplasm	1	Curated	civic	graph →
→ investigated for	Malignant Colorectal Neoplasmsubtype	supports	B	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ investigated for	Malignant Pancreatic Neoplasmcancer	supports	B	Malignant Pancreatic Neoplasm	1	Curated	civic	graph →
→ investigated for	Pancreatic Neoplasmsubtype	unknown	4	Pancreatic Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype	unknown	4	Lung Non-Small Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Lung Adenocarcinomasubtype 21 source records aggregated	supports	C	Lung Adenocarcinoma	21	Curated	civic	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype 8 source records aggregated	supports	C	Lung Non-Small Cell Carcinoma	8	Curated	civic	graph →
→ investigated for	Colon Adenocarcinomasubtype	supports	C	Colon Adenocarcinoma	1	Curated	civic	graph →
→ investigated for	Cholangiocarcinomasubtype	supports	C	Cholangiocarcinoma	1	Curated	civic	graph →
→ investigated for	Lung Acinar Adenocarcinomasubtype	supports	C	Lung Acinar Adenocarcinoma	1	Curated	civic	graph →
→ investigated for	Pancreatic Adenocarcinomasubtype	supports	C	Pancreatic Adenocarcinoma	1	Curated	civic	graph →
→ investigated for	Minimally Invasive Lung Adenocarcinomasubtype	supports	C	Minimally Invasive Lung Adenocarcinoma	1	Curated	civic	graph →
→ investigated for	Lung Squamous Cell Carcinomasubtype	supports	C	Lung Squamous Cell Carcinoma	1	Curated	civic	graph →
→ investigated for	Head and Neck Squamous Cell Carcinomasubtype	supports	C	Head and Neck Squamous Cell Carcinoma	1	Curated	civic	graph →
→ investigated for	Lung Neoplasmcancer_family	unknown	3	Lung Neoplasm	1	Curated	chembl	graph →
→ investigated for	Fallopian Tube Neoplasmsubtype	unknown	3	Fallopian Tube Neoplasm	1	Curated	chembl	graph →
→ investigated for	Peritoneal Neoplasmcancer_family	unknown	3	Peritoneal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Colorectal Neoplasmsubtype	unknown	3	Colorectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Lung Adenocarcinomasubtype	unknown	3	Lung Adenocarcinoma	1	Curated	chembl	graph →
→ investigated for	Esophageal Neoplasmcancer_family	unknown	3	Esophageal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Ovarian Neoplasmsubtype	unknown	3	Ovarian Neoplasm	1	Curated	chembl	graph →
→ investigated for	Hepatocellular Carcinomasubtype	unknown	3	Hepatocellular Carcinoma	1	Curated	chembl	graph →
→ investigated for	Head and Neck Neoplasmcancer_family	unknown	3	Head and Neck Neoplasm	1	Curated	chembl	graph →
→ investigated for	Large Cell Carcinomahistology	unknown	3	Large Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Oral Cavity Neoplasmsubtype	unknown	3	Oral Cavity Neoplasm	1	Curated	chembl	graph →
→ investigated for	Neoplasmcancer_family	unknown	3	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Squamous Cell Carcinomahistology	unknown	3	Squamous Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Lung Non-Small Cell Carcinomasubtype 15 source records aggregated	supports	D	Lung Non-Small Cell Carcinoma	15	Curated	civic	graph →
→ investigated for	Malignant Neoplasmcancer_family 13 source records aggregated	supports	D	Malignant Neoplasm	13	Curated	civic	graph →
→ investigated for	High-Grade Glioma, NOSsubtype 6 source records aggregated	supports	D	High-Grade Glioma, NOS	6	Curated	civic	graph →
→ investigated for	Lung Small Cell Carcinomasubtype	supports	D	Lung Small Cell Carcinoma	1	Curated	civic	graph →
→ investigated for	Lung Adenocarcinomasubtype	supports	D	Lung Adenocarcinoma	1	Curated	civic	graph →
→ investigated for	Malignant Colorectal Neoplasmsubtype	supports	D	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ investigated for	Bile Duct Neoplasmsubtype	unknown	2	Bile Duct Neoplasm	1	Curated	chembl	graph →
→ investigated for	Gallbladder Neoplasmsubtype	unknown	2	Gallbladder Neoplasm	1	Curated	chembl	graph →
→ investigated for	Cholangiocarcinomasubtype	unknown	2	Cholangiocarcinoma	1	Curated	chembl	graph →
→ investigated for	Hematopoietic and Lymphoid Cell Neoplasmcancer_family	unknown	2	Hematopoietic and Lymphoid Cell Neoplasm	1	Curated	chembl	graph →
→ investigated for	Skin Neoplasmcancer_family	unknown	2	Skin Neoplasm	1	Curated	chembl	graph →
→ investigated for	Neuroendocrine Tumorsubtype	unknown	2	Neuroendocrine Tumor	1	Curated	chembl	graph →
→ investigated for	Diffuse Intrinsic Pontine Gliomasubtype	unknown	2	Diffuse Intrinsic Pontine Glioma	1	Curated	chembl	graph →
→ investigated for	Colon Neoplasmsubtype	unknown	2	Colon Neoplasm	1	Curated	chembl	graph →
→ investigated for	Endometrial Neoplasmsubtype	unknown	2	Endometrial Neoplasm	1	Curated	chembl	graph →
→ investigated for	Liver Neoplasmsubtype	unknown	2	Liver Neoplasm	1	Curated	chembl	graph →
→ investigated for	Kidney Neoplasmsubtype	unknown	2	Kidney Neoplasm	1	Curated	chembl	graph →
→ investigated for	Bladder Neoplasmsubtype	unknown	2	Bladder Neoplasm	1	Curated	chembl	graph →
→ investigated for	Central Nervous System Neoplasmcancer_family	unknown	2	Central Nervous System Neoplasm	1	Curated	chembl	graph →
→ investigated for	Thymomasubtype	unknown	2	Thymoma	1	Curated	chembl	graph →
→ investigated for	Nasopharyngeal Neoplasmsubtype	unknown	2	Nasopharyngeal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Acute Myeloid Leukemiahematologic_malignancy	unknown	2	Acute Myeloid Leukemia	1	Curated	chembl	graph →
→ investigated for	Gliosarcomasubtype	unknown	2	Gliosarcoma	1	Curated	chembl	graph →
→ investigated for	Rectal Neoplasmsubtype	unknown	2	Rectal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Triple-Negative Breast Carcinomamolecular_subtype	unknown	2	Triple-Negative Breast Carcinoma	1	Curated	chembl	graph →
→ investigated for	Melanomacancer_family	unknown	2	Melanoma	1	Curated	chembl	graph →
→ investigated for	Sarcomacancer_family	unknown	2	Sarcoma	1	Curated	chembl	graph →
→ investigated for	Glioblastomasubtype	unknown	2	Glioblastoma	1	Curated	chembl	graph →
→ investigated for	Carcinomacancer_family	unknown	2	Carcinoma	1	Curated	chembl	graph →
→ investigated for	Polycythemia Verahematologic_malignancy	unknown	2	Polycythemia Vera	1	Curated	chembl	graph →
→ investigated for	Minimally Invasive Lung Adenocarcinomasubtype	unknown	2	Minimally Invasive Lung Adenocarcinoma	1	Curated	chembl	graph →
→ investigated for	Myelodysplastic Syndromehematologic_malignancy	unknown	2	Myelodysplastic Syndrome	1	Curated	chembl	graph →
→ investigated for	Leukemiacancer_family	unknown	2	Leukemia	1	Curated	chembl	graph →
→ investigated for	Ependymomasubtype	unknown	2	Ependymoma	1	Curated	chembl	graph →
→ investigated for	Renal Cell Carcinomasubtype	unknown	2	Renal Cell Carcinoma	1	Curated	chembl	graph →
→ investigated for	Malignant Mesotheliomacancer_family	unknown	2	Malignant Mesothelioma	1	Curated	chembl	graph →
→ investigated for	Brain Neoplasmsubtype	unknown	2	Brain Neoplasm	1	Curated	chembl	graph →
→ investigated for	Breast Neoplasmcancer_family	unknown	2	Breast Neoplasm	1	Curated	chembl	graph →
→ investigated for	Multiple Myelomahematologic_malignancy	unknown	1	Multiple Myeloma	1	Curated	chembl	graph →
→ investigated for	Oropharyngeal Neoplasmsubtype	unknown	1	Oropharyngeal Neoplasm	1	Curated	chembl	graph →
→ investigated for	Meningiomasubtype	unknown	1	Meningioma	1	Curated	chembl	graph →
→ investigated for	Gliomasubtype	unknown	1	Glioma	1	Curated	chembl	graph →
→ investigated for	Cervical Neoplasmsubtype	unknown	1	Cervical Neoplasm	1	Curated	chembl	graph →
→ investigated for	Salivary Gland Neoplasmcancer_family	unknown	1	Salivary Gland Neoplasm	1	Curated	chembl	graph →
→ investigated for	Astrocytic Tumorsubtype	unknown	1	Astrocytic Tumor	1	Curated	chembl	graph →
→ investigated for	Oligodendrogliomasubtype	unknown	1	Oligodendroglioma	1	Curated	chembl	graph →
→ investigated for	Pharyngeal Neoplasmsubtype	unknown	0.5	Pharyngeal Neoplasm	1	Curated	chembl	graph →

Erlotinib investigated for …INVESTIGATED_FOR78 of 78show fewer

→ investigated for

4 source records aggregated

supports

Curated

→ investigated for

26 source records aggregated

supports

Curated

→ investigated for

5 source records aggregated

supports

Curated

→ investigated for

Glioblastomasubtype

2 source records aggregated

supports

Glioblastoma

Curated

→ investigated for

Malignant Lung Neoplasmcancer

supports

Malignant Lung Neoplasm

Curated

Malignant Colorectal Neoplasm

→ investigated for

Malignant Colorectal Neoplasmsubtype

supports

Curated

Malignant Pancreatic Neoplasm

→ investigated for

Malignant Pancreatic Neoplasmcancer

supports

Curated

→ investigated for

Pancreatic Neoplasmsubtype

unknown

Pancreatic Neoplasm

Curated

→ investigated for

unknown

Curated

→ investigated for

21 source records aggregated

supports

Curated

→ investigated for

8 source records aggregated

supports

Curated

→ investigated for

Colon Adenocarcinomasubtype

supports

Colon Adenocarcinoma

Curated

→ investigated for

Cholangiocarcinomasubtype

supports

Cholangiocarcinoma

Curated

Lung Acinar Adenocarcinoma

→ investigated for

Lung Acinar Adenocarcinomasubtype

supports

Curated

Pancreatic Adenocarcinoma

→ investigated for

Pancreatic Adenocarcinomasubtype

supports

Curated

Minimally Invasive Lung Adenocarcinoma

→ investigated for

Minimally Invasive Lung Adenocarcinomasubtype

supports

Curated

Lung Squamous Cell Carcinoma

→ investigated for

Lung Squamous Cell Carcinomasubtype

supports

Curated

Head and Neck Squamous Cell Carcinoma

→ investigated for

Head and Neck Squamous Cell Carcinomasubtype

supports

Curated

→ investigated for

Lung Neoplasmcancer_family

unknown

Lung Neoplasm

Curated

→ investigated for

Fallopian Tube Neoplasmsubtype

unknown

Fallopian Tube Neoplasm

Curated

→ investigated for

Peritoneal Neoplasmcancer_family

unknown

Peritoneal Neoplasm

Curated

→ investigated for

Colorectal Neoplasmsubtype

unknown

Colorectal Neoplasm

Curated

→ investigated for

unknown

Curated

→ investigated for

Esophageal Neoplasmcancer_family

unknown

Esophageal Neoplasm

Curated

→ investigated for

Ovarian Neoplasmsubtype

unknown

Ovarian Neoplasm

Curated

→ investigated for

Hepatocellular Carcinomasubtype

unknown

Hepatocellular Carcinoma

Curated

→ investigated for

Head and Neck Neoplasmcancer_family

unknown

Head and Neck Neoplasm

Curated

→ investigated for

Large Cell Carcinomahistology

unknown

Large Cell Carcinoma

Curated

→ investigated for

Oral Cavity Neoplasmsubtype

unknown

Oral Cavity Neoplasm

Curated

→ investigated for

Neoplasmcancer_family

unknown

Neoplasm

Curated

→ investigated for

Squamous Cell Carcinomahistology

unknown

Squamous Cell Carcinoma

Curated

→ investigated for

15 source records aggregated

supports

Curated

→ investigated for

Malignant Neoplasmcancer_family

13 source records aggregated

supports

Malignant Neoplasm

Curated

→ investigated for

High-Grade Glioma, NOSsubtype

6 source records aggregated

supports

High-Grade Glioma, NOS

Curated

Lung Small Cell Carcinoma

→ investigated for

Lung Small Cell Carcinomasubtype

supports

Curated

→ investigated for

supports

Curated

Malignant Colorectal Neoplasm

→ investigated for

Malignant Colorectal Neoplasmsubtype

supports

Curated

→ investigated for

Bile Duct Neoplasmsubtype

unknown

Bile Duct Neoplasm

Curated

→ investigated for

Gallbladder Neoplasmsubtype

unknown

Gallbladder Neoplasm

Curated

→ investigated for

Cholangiocarcinomasubtype

unknown

Cholangiocarcinoma

Curated

Hematopoietic and Lymphoid Cell Neoplasm

→ investigated for

Hematopoietic and Lymphoid Cell Neoplasmcancer_family

unknown

Curated

→ investigated for

Skin Neoplasmcancer_family

unknown

Skin Neoplasm

Curated

→ investigated for

Neuroendocrine Tumorsubtype

unknown

Neuroendocrine Tumor

Curated

Diffuse Intrinsic Pontine Glioma

→ investigated for

Diffuse Intrinsic Pontine Gliomasubtype

unknown

Curated

→ investigated for

Colon Neoplasmsubtype

unknown

Colon Neoplasm

Curated

→ investigated for

Endometrial Neoplasmsubtype

unknown

Endometrial Neoplasm

Curated

→ investigated for

Liver Neoplasmsubtype

unknown

Liver Neoplasm

Curated

→ investigated for

Kidney Neoplasmsubtype

unknown

Kidney Neoplasm

Curated

→ investigated for

Bladder Neoplasmsubtype

unknown

Bladder Neoplasm

Curated

Central Nervous System Neoplasm

→ investigated for

Central Nervous System Neoplasmcancer_family

unknown

Curated

→ investigated for

Thymomasubtype

unknown

Thymoma

Curated

→ investigated for

Nasopharyngeal Neoplasmsubtype

unknown

Nasopharyngeal Neoplasm

Curated

→ investigated for

Acute Myeloid Leukemiahematologic_malignancy

unknown

Acute Myeloid Leukemia

Curated

→ investigated for

Gliosarcomasubtype

unknown

Gliosarcoma

Curated

→ investigated for

Rectal Neoplasmsubtype

unknown

Rectal Neoplasm

Curated

Triple-Negative Breast Carcinoma

→ investigated for

Triple-Negative Breast Carcinomamolecular_subtype

unknown

Curated

→ investigated for

Melanomacancer_family

unknown

Melanoma

Curated

→ investigated for

Sarcomacancer_family

unknown

Sarcoma

Curated

→ investigated for

Glioblastomasubtype

unknown

Glioblastoma

Curated

→ investigated for

Carcinomacancer_family

unknown

Carcinoma

Curated

→ investigated for

Polycythemia Verahematologic_malignancy

unknown

Polycythemia Vera

Curated

Minimally Invasive Lung Adenocarcinoma

→ investigated for

Minimally Invasive Lung Adenocarcinomasubtype

unknown

Curated

→ investigated for

Myelodysplastic Syndromehematologic_malignancy

unknown

Myelodysplastic Syndrome

Curated

→ investigated for

Leukemiacancer_family

unknown

Leukemia

Curated

→ investigated for

Ependymomasubtype

unknown

Ependymoma

Curated

→ investigated for

Renal Cell Carcinomasubtype

unknown

Renal Cell Carcinoma

Curated

→ investigated for

Malignant Mesotheliomacancer_family

unknown

Malignant Mesothelioma

Curated

→ investigated for

Brain Neoplasmsubtype

unknown

Brain Neoplasm

Curated

→ investigated for

Breast Neoplasmcancer_family

unknown

Breast Neoplasm

Curated

→ investigated for

Multiple Myelomahematologic_malignancy

unknown

Multiple Myeloma

Curated

→ investigated for

Oropharyngeal Neoplasmsubtype

unknown

Oropharyngeal Neoplasm

Curated

→ investigated for

Meningiomasubtype

unknown

Meningioma

Curated

→ investigated for

Gliomasubtype

unknown

Glioma

Curated

→ investigated for

Cervical Neoplasmsubtype

unknown

Cervical Neoplasm

Curated

→ investigated for

Salivary Gland Neoplasmcancer_family

unknown

Salivary Gland Neoplasm

Curated

→ investigated for

Astrocytic Tumorsubtype

unknown

Astrocytic Tumor

Curated

→ investigated for

Oligodendrogliomasubtype

unknown

Oligodendroglioma

Curated

→ investigated for

Pharyngeal Neoplasmsubtype

unknown

0.5

Pharyngeal Neoplasm

Curated

Erlotinib investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 144show all (up to 200)
→ investigated in trials for	Lung Non-Small Cell Carcinomasubtype 168 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Small Cell Carcinoma	168	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Lung Neoplasmcancer 30 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Lung Neoplasm	30	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Pancreatic Neoplasmcancer 29 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Pancreatic Neoplasm	29	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Non-Squamous Non-Small Cell Carcinoma 25 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Squamous Non-Small Cell Carcinoma	25	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Neoplasmcancer_family 22 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Neoplasm	22	Observed	clinicaltrials	graph →
→ investigated in trials for	Solid Neoplasm 22 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Solid Neoplasm	22	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Head and Neck Neoplasm 15 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Head and Neck Neoplasm	15	Observed	clinicaltrials	graph →
→ investigated in trials for	Neoplasmcancer_family 10 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Neoplasm	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Breast Neoplasm 9 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Breast Neoplasm	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Colorectal Neoplasmsubtype 9 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Colorectal Neoplasm	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Hepatocellular Carcinomasubtype 6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Hepatocellular Carcinoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Neoplasmcancer_family 6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Neoplasm	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Pancreatic Adenocarcinomasubtype 6 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Pancreatic Adenocarcinoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Brain Neoplasmsubtype 5 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Brain Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Renal Cell Carcinomasubtype 4 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Renal Cell Carcinoma	4	Observed	clinicaltrials	graph →

Erlotinib investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 144show all (up to 200)

→ investigated in trials for

168 trials (6 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

168

Observed

→ investigated in trials for

Malignant Lung Neoplasmcancer

30 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Lung Neoplasm

Observed

Malignant Pancreatic Neoplasm

→ investigated in trials for

Malignant Pancreatic Neoplasmcancer

29 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

Lung Non-Squamous Non-Small Cell Carcinoma

→ investigated in trials for

25 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Lung Non-Squamous Non-Small Cell Carcinoma

Observed

→ investigated in trials for

Malignant Neoplasmcancer_family

22 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Neoplasm

Observed

→ investigated in trials for

Solid Neoplasm

22 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Solid Neoplasm

Observed

Malignant Head and Neck Neoplasm

→ investigated in trials for

15 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Head and Neck Neoplasm

Observed

→ investigated in trials for

Neoplasmcancer_family

10 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Neoplasm

Observed

Malignant Breast Neoplasm

→ investigated in trials for

9 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Breast Neoplasm

Observed

Malignant Colorectal Neoplasm

→ investigated in trials for

Malignant Colorectal Neoplasmsubtype

9 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Hepatocellular Carcinomasubtype

6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Hepatocellular Carcinoma

Observed

→ investigated in trials for

Lung Neoplasmcancer_family

6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Lung Neoplasm

Observed

Pancreatic Adenocarcinoma

→ investigated in trials for

Pancreatic Adenocarcinomasubtype

6 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Observed

→ investigated in trials for

Brain Neoplasmsubtype

5 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Brain Neoplasm

Observed

→ investigated in trials for

Renal Cell Carcinomasubtype

4 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Renal Cell Carcinoma

Observed

Malignant Lung Neoplasm,Lung Non-Small Cell Carcinoma

Erlotinib studied in …STUDIED_INderived10 of 401show all (up to 200)
→ studied in	NCT02194738NA · active not recruiting Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial) · 401 trials list this drug (13 active)	—	—	Malignant Lung Neoplasm,Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04981509Phase 2 · recruiting Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer · 401 trials list this drug (13 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma,Papillary Renal Cell Carcinoma,Renal Cell Carcinoma+1	1	Observed	clinicaltrials	graph →
→ studied in	NCT04449874Phase 1 · active not recruiting A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation · 401 trials list this drug (13 active)	—	—	Solid Neoplasm,Lung Non-Small Cell Carcinoma,Malignant Colorectal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT01562028Phase 2 · completed BELIEF (Bevacizumab and ErLotinib In EGFR Mut+ NSCLC) · 401 trials list this drug (13 active)	—	—	Malignant Lung Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT01652469Phase 3 · completed Testing of Drugs Erlotinib and Docetaxel in Lung Cancer Patients Classified Regarding Their Outlook Using VeriStrat®. · 401 trials list this drug (13 active)	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05827614Phase 1 · terminated Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications · 401 trials list this drug (13 active)	—	—	Cervical Squamous Cell Carcinoma,Head and Neck Squamous Cell Carcinoma,Leiomyosarcoma+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT00640978Phase 2 · terminated Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer · 401 trials list this drug (13 active)	—	—	Malignant Pancreatic Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT00942734Phase 2 · completed Trial of RAD001 and Erlotinib With Recurrent Head and Neck Squamous Cell Carcinoma · 401 trials list this drug (13 active)	—	—	Malignant Head and Neck Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05525858recruiting KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II · 401 trials list this drug (13 active)	—	—	Malignant Neoplasm,Solid Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT00304278Phase 2 · completed Study of RADPLAT and Tarceva in Locally Advanced Head and Neck Squamous Cell Carcinoma (SCCA) · 401 trials list this drug (13 active)	—	—	Malignant Head and Neck Neoplasm	1	Observed	clinicaltrials	graph →

Erlotinib studied in …STUDIED_INderived10 of 401show all (up to 200)

→ studied in

NCT02194738NA · active not recruiting

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial) · 401 trials list this drug (13 active)

—

Observed

Hereditary Leiomyomatosis and Renal Cell Carcinoma,Papillary Renal Cell Carcinoma,Renal Cell Carcinoma+1

→ studied in

NCT04981509Phase 2 · recruiting

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer · 401 trials list this drug (13 active)

—

Observed

Solid Neoplasm,Lung Non-Small Cell Carcinoma,Malignant Colorectal Neoplasm

→ studied in

NCT04449874Phase 1 · active not recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation · 401 trials list this drug (13 active)

—

Observed

→ studied in

NCT01562028Phase 2 · completed

BELIEF (Bevacizumab and ErLotinib In EGFR Mut+ NSCLC) · 401 trials list this drug (13 active)

—

Malignant Lung Neoplasm

Observed

→ studied in

NCT01652469Phase 3 · completed

Testing of Drugs Erlotinib and Docetaxel in Lung Cancer Patients Classified Regarding Their Outlook Using VeriStrat®. · 401 trials list this drug (13 active)

—

Observed

Cervical Squamous Cell Carcinoma,Head and Neck Squamous Cell Carcinoma,Leiomyosarcoma+2

→ studied in

NCT05827614Phase 1 · terminated

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications · 401 trials list this drug (13 active)

—

Observed

Malignant Pancreatic Neoplasm

→ studied in

NCT00640978Phase 2 · terminated

Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer · 401 trials list this drug (13 active)

—

Observed