Invasive Breast Carcinoma

subtype

Identifier: CI-CAN-00002953
Entity page: /cancer/invasive-breast-carcinoma ↗
Edges: 652

Neighbours: 200 genes15 drugs10 trials
Drawn: 60 of 225 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Invasive Breast Carcinoma altered in cohorts of …ALTERED_INderived200 of 276show all (up to 200)
← altered in cohorts of	OBSCN 806 / 1,098 cases (73 %) · ssm · TCGA-BRCA · largest of 3 cohorts	—	—	Breast Invasive Carcinoma, NOS	3	Observed	gdc	graph →
← altered in cohorts of	PIK3C2B 804 / 1,098 cases (73 %) · ssm · TCGA-BRCA

Invasive Breast Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 80show all (up to 200)

→ investigated in trials for

Paclitaxelsmall molecule

26 trials (9 active) · roll-up of the cancer and its descendants

—

Invasive Breast Carcinoma

Observed

Invasive Breast Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 80show all (up to 200)
→ investigated in trials for	Paclitaxelsmall molecule 26 trials (9 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	26	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 22 trials (6 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	22	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 18 trials (9 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	18	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall molecule 13 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Letrozolesmall molecule 13 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Trastuzumabmonoclonal antibody 13 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 11 trials (8 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	11	Observed	clinicaltrials	graph →
→ investigated in trials for	Anastrozolesmall molecule 9 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Fulvestrantsmall molecule 8 trials (2 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Nab-paclitaxel 8 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Pertuzumabmonoclonal antibody 8 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Docetaxelsmall molecule 7 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Tamoxifensmall molecule 7 trials (1 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Atezolizumabmonoclonal antibody 6 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Capecitabinesmall molecule 6 trials (2 active) · roll-up of the cancer and its descendants	—	—	Invasive Breast Carcinoma	6	Observed	clinicaltrials	graph →

Invasive Breast Carcinoma studied in …STUDIED_INderived10 of 296show all (up to 200)
→ studied in	NCT02883062Phase 2 · active not recruiting Carboplatin and Paclitaxel With or Without Atezolizumab Before Surgery in Treating Patients With Newly Diagnosed, Stage II-III Triple-Negative Breast Cancer · condition mapped ONTOLOGY_EXACT · 296 trials mapped (122 active)	—	—	Invasive Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03598257Phase 2 · active not recruiting Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer · condition mapped ONTOLOGY_EXACT · 296 trials mapped (122 active)	—	—	Breast Inflammatory Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02945579NA · recruiting Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy · condition mapped ONTOLOGY_EXACT · 296 trials mapped (122 active)	—	—	Invasive Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02860000Phase 2 · completed Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer · condition mapped ONTOLOGY_EXACT · 296 trials mapped (122 active)	—	—	Invasive Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05412225Phase 1 · recruiting A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer · condition mapped ALIAS · 296 trials mapped (122 active)	—	—	Invasive Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03387553early Phase 1 · completed HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer · condition mapped ALIAS · 296 trials mapped (122 active)	—	—	Invasive Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04084730Phase 2 · recruiting Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer · condition mapped ALIAS · 296 trials mapped (122 active)	—	—	Invasive Breast Carcinoma of No Special Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT01334021Phase 2 · active not recruiting Genetic Testing in Predicting Tumor Response in Patients With Stage I-III HER2 Negative Invasive Breast Cancer · condition mapped ONTOLOGY_EXACT · 296 trials mapped (122 active)	—	—	Invasive Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07819045NA · completed Self-Acceptance and Supportive Accountability for Active Living Among Adults Receiving Chemotherapy · condition mapped CURATED_BROADER · 296 trials mapped (122 active)	—	—	Invasive Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02453620Phase 1 · active not recruiting Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer · condition mapped ONTOLOGY_EXACT · 296 trials mapped (122 active)	—	—	Invasive Breast Carcinoma	1	Observed	clinicaltrials	graph →

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