Thymus Epithelial Neoplasm — Genomics

Thymus Epithelial Neoplasm — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

5 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Thymic Epithelial Tumors (NCI, Nat Genet 2014) tet_nci_2014NCI

32 cases with simple somatic mutation data · 32 cases total · 2026-01-13 · mapped to Thymus Epithelial Neoplasm EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	GTF2I	Ssm	6	32	18.8%	cbioportal
2	TP53	Ssm	3	32	9.4%	cbioportal
16	TAF1L	Ssm	2	32	6.3%	cbioportal
15	PKHD1L1	Ssm	2	32	6.3%	cbioportal
14	PAM	Ssm	2	32	6.3%	cbioportal
13	NIPBL	Ssm	2	32	6.3%	cbioportal
12	MYOCD	Ssm	2	32	6.3%	cbioportal
11	KIR2DL3

Data updated 22 days agoSource updated 2026-01-13

Thymoma TCGA-THYMTCGA

124 cases with simple somatic mutation data · 124 cases total · Data Release 46.0 · mapped to Thymoma ONTOLOGY_EXACT

gdcObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	GTF2I	Ssm

Thymoma (TCGA, Firehose Legacy) thym_tcgaTCGA

123 cases with simple somatic mutation data · 124 cases total · 2026-01-13 · mapped to Thymoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	GTF2I	Ssm	49	123	39.8%

Thymoma (TCGA GDC, 2025) thym_tcga_gdcTCGA GDC

121 cases with simple somatic mutation data · 124 cases total · 2026-01-14 · mapped to Thymoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	GTF2I	Ssm	62	121	51.2%

Thymoma (TCGA, PanCancer Atlas) thym_tcga_pan_can_atlas_2018TCGA

123 cases with simple somatic mutation data · 123 cases total · 2026-06-04 · mapped to Thymoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	GTF2I

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.