Gene
PREX1
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
Explore in graph →CI-GENE-00020944HGNC:32594 ENSG00000124126 NCBI 57580 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (23)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Breast Cancer (HTAN, 2022) brca_hta9_htan_2022 | Invasive Breast Carcinoma | Ssm | 5 | 5 | 100% | 21 | cbioportal |
| Rectum Adenocarcinoma TCGA-READ | Rectal AdenocarcinomaALIAS |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.