Gene
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4
Explore in graph →CI-GENE-00000441HGNC:220 ENSG00000158859 NCBI 9507 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (17)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33863915
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metaplastic Breast Cancer (MSK,NPJ Breast Cancer 2021) mbc_msk_2021 | Breast Metaplastic Carcinoma | Ssm | 1 | 5 | 20% | 24 | cbioportal |
| Primary Central Nervous System Lymphoma (Mayo Clinic, Clin Cancer Res 2015) pcnsl_mayo_2015 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.