Gene
ITGB2
integrin subunit beta 2
Explore in graph →CI-GENE-00006430HGNC:6155 ENSG00000160255 NCBI 3689 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 35504881
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Prostate Cancer Brain Metastases (Bern, Nat Commun. 2022) prostate_pcbm_swiss_2019 | unmapped | Ssm | 15 | 168 | 8.9% | 51 | cbioportal |
| Thymic Epithelial Tumors (NCI, Nat Genet 2014) tet_nci_2014 | Thymus Epithelial Neoplasm | Ssm | 2 | 32 | 6.3% | 9 | cbioportal |
| Glioblastoma Multiforme (TCGA, PanCancer Atlas) gbm_tcga_pan_can_atlas_2018 | Diffuse Glioma | Ssm | 11 | 397 | 2.8% | 152 | cbioportal |
| Glioblastoma (TCGA, Nature 2008) gbm_tcga_pub | Diffuse Glioma | Ssm | 2 | 91 | 2.2% | 43 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.