Gene
ADAM19
ADAM metallopeptidase domain 19
Explore in graph →CI-GENE-00000419HGNC:197 ENSG00000135074 NCBI 8728 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (9)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 32649874
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lung Adenocarcinoma (CPTAC, Cell 2020) luad_cptac_2020 | Lung Adenocarcinoma | Ssm | 9 | 110 | 8.2% | 166 | cbioportal |
| Acral Melanoma (TGEN, Genome Res 2017) mel_tsam_liang_2017 | Melanoma | Ssm | 3 | 38 | 7.9% | 134 | cbioportal |
| Neuroendocrine Prostate Cancer (Multi-Institute, Nat Med 2016) nepc_wcm_2016 | Prostate Adenocarcinoma | Ssm | 6 | 114 | 5.3% | 35 | cbioportal |
| Thymic Epithelial Tumors (NCI, Nat Genet 2014) tet_nci_2014 | Thymus Epithelial Neoplasm | Ssm | 1 | 32 | 3.1% | 26 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.